Publications by authors named "Julian Mark"

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Balancing brain exposure, pharmacokinetics and safety of transferrin receptor antibodies for delivery of neuro-therapeutics.
Benjamin A Smith, Caitlin B Meeks, Isabel Murray-Brown, Elizabeth A McCarthy, Mark C Julian

MAbs· December 2025

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Signal regulating proteins (SIRPs) participate in sarcoidosis granuloma formation by promoting immune cell aggregation.
Marc A Judson, Mark W Julian, Llewellyn Foulke, Sandip Panicker, Soe H Arker

Respir Res· December 2025

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Parkinson's-Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa.
Julian R Mark, Hannah A Staley, Ann M Titus, Julian Agin-Liebes, Alicia Garrido

Mov Disord· November 2025

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Peripheral immune cell response to stimulation stratifies Parkinson's disease progression from prodromal to clinical stages.
Julian R Mark, Ann M Titus, Hannah A Staley, Stephan Alvarez, Savanna Mahn

Commun Biol· May 2025

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ASO-mediated knock-down of GPNMB in mutant-GRN and in Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses.
Rebecca L Wallings, Drew A Gillett, Hannah A Staley, Savanna Mahn, Julian Mark

Mol Neurodegener· April 2025

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Immune cell metabolic dysfunction in Parkinson's disease.
Julian R Mark, Malú Gámez Tansey

Mol Neurodegener· March 2025

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Therapeutic doses of efzofitimod demonstrate efficacy in pulmonary sarcoidosis.
Ogugua Ndili Obi, Robert P Baughman, Elliott D Crouser, Mark W Julian, Landon W Locke

ERJ Open Res· January 2025

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Peripheral immune cell response to stimulation stratifies Parkinson's disease progression from prodromal to clinical stages.
Julian R Mark, Ann M Titus, Hannah A Staley, Stephan Alvarez, Savanna Mahn

bioRxiv· December 2024

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Development of a centralised national AED (automated external defibrillator) network across all ambulance services in the United Kingdom.
Judy O'Sullivan, Edward Moore, Simon Dunn, Helen Tennant, Dexter Smith, Julian Mark

Resusc Plus· September 2024

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The Renin-Angiotensin-Aldosterone System Regulates Sarcoidosis Granulomatous Inflammation.
Elliott D Crouser, Mark W Julian, Landon W Locke, Sabahattin Bicer, Jonah R Mitchell

Am J Respir Crit Care Med· August 2024

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ASO-mediated knockdown of GPNMB in mutant- and -deficient peripheral myeloid cells disrupts lysosomal function and immune responses.
Rebecca L Wallings, Drew A Gillett, Hannah A Staley, Savanna Mahn, Julian Mark

bioRxiv· July 2024

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Investigating cryopreserved PBMC functionality in an antigen-induced model of sarcoidosis granuloma formation.
Sarah G Seman, Sabahattin Bicer, Mark W Julian, Jonah R Mitchell, Patrick J Kramer

Biochem Biophys Res Commun· June 2024

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High dose dietary vitamin D allocates surplus calories to muscle and growth instead of fat via modulation of myostatin and leptin signaling.
Jeffrey Roizen, Caela Long, Alex Casella, Michael Nguyen, Lo Danahy, Julian Mark

Res Sq· May 2024

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Dietary vitamin D is a novel modulator of tumor engraftment through regulation of GC protein abundance.
Lo Danahy, Caela Long, Ted J Hofmann, Zahra Tara, Julian Mark

Res Sq· February 2024

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Blood collection in heparin vs. EDTA results in an inflammasome-independent increase in monocyte distribution width at 4 h.
Gregory J Eisinger, Wissam Osman, Evan R Prather, Mark W Julian, Mikhail A Gavrilin, Mark D Wewers

Clin Chem Lab Med· January 2024

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ASO-mediated knockdown or kinase inhibition of -Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages.
Rebecca L Wallings, Julian R Mark, Hannah A Staley, Drew A Gillett, Noelle Neighbarger

Mol Ther Nucleic Acids· December 2023

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Totally tubular: ASO-mediated knock-down of -Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages.
Rebecca L Wallings, Julian R Mark, Hannah A Staley, Drew A Gillett, Noelle Neighbarger

bioRxiv· July 2023

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Leveraging and pharmacokinetic models to support bench to bedside investigation of XTMAB-16 as a novel pulmonary sarcoidosis treatment.
Elliot Offman, Noopur Singh, Mark W Julian, Landon W Locke, Sabahattin Bicer

Front Pharmacol· March 2023

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Inflammasome Activation in an In Vitro Sepsis Model Recapitulates Increased Monocyte Distribution Width Seen in Patients With Sepsis.
Gregory J Eisinger, Wissam Osman, Evan R Prather, Mark W Julian, Mikhail A Gavrilin, Mark D Wewers

Crit Care Explor· February 2022

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A Pilot Randomized Trial of Transdermal Nicotine for Pulmonary Sarcoidosis.
Elliott D Crouser, Rachel M Smith, Daniel A Culver, Mark W Julian, Karen Martin

Chest· October 2021

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Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains.
Johan Nilvebrant, June Ereño-Orbea, Maryna Gorelik, Mark C Julian, Peter M Tessier

J Mol Biol· October 2021

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Circulating exosomal microRNA expression patterns distinguish cardiac sarcoidosis from myocardial ischemia.
Elliott D Crouser, Mark W Julian, Sabahattin Bicer, Vikas Ghai, Taek-Kyun Kim

PLoS One· June 2021

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Phagosome-regulated mTOR signalling during sarcoidosis granuloma biogenesis.
Elliott D Crouser, Landon W Locke, Mark W Julian, Sabahattin Bicer, Wolfgang Sadee

Eur Respir J· March 2021

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Monocyte Distribution Width: A Novel Indicator of Sepsis-2 and Sepsis-3 in High-Risk Emergency Department Patients.
Elliott D Crouser, Joseph E Parrillo, Christopher W Seymour, Derek C Angus, Keri Bicking, Mark W Julian

Crit Care Med· August 2019

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Nature-inspired design and evolution of anti-amyloid antibodies.
Mark C Julian, Lilia A Rabia, Alec A Desai, Ammar Arsiwala, Julia E Gerson

J Biol Chem· May 2019

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