Publications by authors named "Juliana Layzer"

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An RNA aptamer exploits exosite-dependent allostery to achieve specific inhibition of coagulation factor IXa.
Vladimir N Kolyadko, Juliana M Layzer, Kay Perry, Bruce A Sullenger, Sriram Krishnaswamy

Proc Natl Acad Sci U S A· July 2024

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Aptameric hirudins as selective and reversible EXosite-ACTive site (EXACT) inhibitors.
Haixiang Yu, Shekhar Kumar, James W Frederiksen, Vladimir N Kolyadko, George Pitoc, Juliana Layzer

Nat Commun· May 2024

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Utilizing directed evolution to interrogate and optimize CRISPR/Cas guide RNA scaffolds.
Korie Bush, Giulia I Corsi, Amy C Yan, Keith Haynes, Juliana M Layzer

Cell Chem Biol· August 2023

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Rapid molecular imaging of active thrombi using aptamer-antidote probes.
Bethany Powell Gray, Linsley Kelly, Kady-Ann Steen-Burrell, Juliana M Layzer, Rachel E Rempel

Mol Ther Nucleic Acids· March 2023

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PEG-Like Brush Polymer Conjugate of RNA Aptamer That Shows Reversible Anticoagulant Activity and Minimal Immune Response.
Imran Ozer, George A Pitoc, Juliana M Layzer, Angelo Moreno, Lyra B Olson, Kyle D Layzer

Adv Mater· March 2022

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Aptamer-based factor IXa inhibition preserves hemostasis and prevents thrombosis in a piglet model of ECMO.
Christopher R Reed, Desiree Bonadonna, James C Otto, Charles Griffin McDaniel, Charlene Vongai Chabata, Juliana M Layzer

Mol Ther Nucleic Acids· March 2022

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Preclinical Development of a vWF Aptamer to Limit Thrombosis and Engender Arterial Recanalization of Occluded Vessels.
Shahid M Nimjee, David Dornbos, George A Pitoc, Debra G Wheeler, Juliana M Layzer

Mol Ther· July 2019

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Anti-PEG Antibodies Inhibit the Anticoagulant Activity of PEGylated Aptamers.
Angelo Moreno, George A Pitoc, Nancy J Ganson, Juliana M Layzer, Michael S Hershfield

Cell Chem Biol· May 2019

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Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury.
Allyson L Huttinger, Debra G Wheeler, Surya Gnyawali, David Dornbos, Juliana M Layzer

J Vis Exp· September 2018

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An anticoagulant RNA aptamer that inhibits proteinase-cofactor interactions within prothrombinase.
Sai K Buddai, Juliana M Layzer, Genmin Lu, Christopher P Rusconi, Bruce A Sullenger

J Biol Chem· February 2010

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Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer.
Claudia M Dollins, Smita Nair, David Boczkowski, Jaewoo Lee, Juliana M Layzer

Chem Biol· July 2008

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Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia.
Paloma H Giangrande, JianXin Zhang, Alice Tanner, Andrea D Eckhart, Rachel E Rempel, Juliana M Layzer

Proc Natl Acad Sci U S A· August 2007

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Simultaneous generation of aptamers to multiple gamma-carboxyglutamic acid proteins from a focused aptamer library using DeSELEX and convergent selection.
Juliana M Layzer, Bruce A Sullenger

Oligonucleotides· June 2007

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In vivo activity of nuclease-resistant siRNAs.
Juliana M Layzer, Anton P McCaffrey, Alice K Tanner, Zan Huang, Mark A Kay

RNA· May 2004

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RNA aptamers as reversible antagonists of coagulation factor IXa.
Christopher P Rusconi, Elizabeth Scardino, Juliana Layzer, George A Pitoc, Thomas L Ortel

Nature· September 2002

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