Publications by authors named "Julie Blazel"

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6
6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors.
Johnny Y Nagasawa, Jenny Song, Huanming Chen, Hong-Woo Kim, Julie Blazel

Bioorg Med Chem Lett· January 2011

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5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
David A Ellis, Julie K Blazel, Chinh V Tran, Frank Ruebsam, Douglas E Murphy

Bioorg Med Chem Lett· November 2009

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Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase.
Frank Ruebsam, Douglas E Murphy, Chinh V Tran, Lian-Sheng Li, Jingjing Zhao, Julie K Blazel

Bioorg Med Chem Lett· November 2009

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5,6-Dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Frank Ruebsam, Chinh V Tran, Lian-Sheng Li, Sun Hee Kim, Alan X Xiang, Julie K Blazel

Bioorg Med Chem Lett· January 2009

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Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents.
Peter S Dragovich, Julie K Blazel, David A Ellis, Qing Han, Ruhi Kamran

Bioorg Med Chem Lett· October 2008

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4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase.
David A Ellis, Julie K Blazel, Stephen E Webber, Chinh V Tran, Peter S Dragovich

Bioorg Med Chem Lett· August 2008

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Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase.
Sun Hee Kim, Martin T Tran, Frank Ruebsam, Alan X Xiang, Benjamin Ayida, Julie Blazel

Bioorg Med Chem Lett· July 2008

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Allosteric inhibitors of hepatitis C polymerase: discovery of potent and orally bioavailable carbon-linked dihydropyrones.
Hui Li, Angelica Linton, John Tatlock, Javier Gonzalez, Allen Borchardt, Julie Blazel

J Med Chem· August 2007

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Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors.
Hui Li, John Tatlock, Angelica Linton, Javier Gonzalez, Allen Borchardt, Julie Blazel

Bioorg Med Chem Lett· September 2006

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