Publications by authors named "Justin Harrison"

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Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of .
Simon R Green, Justin R Harrison, Stephen Thompson, Dinakaran Murugesan, M Daben J Libardo

ACS Infect Dis· March 2025

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High-energy generation of arbitrary cylindrical vector vortex beams using a modified Mach-Zehnder interferometer.
Justin Harrison, Nokwazi Mphuthi, Chemist Mabena, Darryl Naidoo

Appl Opt· March 2025

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Improving performance prediction of diode end-pumped solid-state Nd:YAG rod amplifiers by incorporating pump mode evolution.
Justin Harrison, Andrew Forbes, Darryl Naidoo

Opt Express· July 2023

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Beam quality factor of aberrated Laguerre-Gaussian optical beams.
Chemist M Mabena, Teboho Bell, Nokwazi Mphuthi, Justin Harrison, Darryl Naidoo

Opt Express· July 2023

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Amplification of higher-order Laguerre-Gaussian modes using a dual-pass MOPA system.
Justin Harrison, Andrew Forbes, Darryl Naidoo

Opt Express· May 2023

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Aberration-induced vortex splitting in amplified orbital angular momentum beams.
Justin Harrison, Wagner Tavares Buono, Andrew Forbes, Darryl Naidoo

Opt Express· May 2023

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Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis.
Alasdair Smith, Richard J Wall, Stephen Patterson, Tim Rowan, Eva Rico Vidal, Justin R Harrison

J Med Chem· April 2022

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An Evaluation of Wound Healing Efficacy of a Film Dressing Made from Polymer-integrated Amnion Membrane.
Bo Wang, Wuwei Li, Justin Harrison

Organogenesis· October 2020

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Discovery and Optimization of a Compound Series Active against , the Causative Agent of Chagas Disease.
Justin R Harrison, Sandipan Sarkar, Shahienaz Hampton, Jennifer Riley, Laste Stojanovski

J Med Chem· March 2020

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PE/PPE proteins mediate nutrient transport across the outer membrane of .
Qinglan Wang, Helena I M Boshoff, Justin R Harrison, Peter C Ray, Simon R Green

Science· March 2020

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A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors.
Justin R Harrison, Stephen Brand, Victoria Smith, David A Robinson, Stephen Thompson

J Med Chem· September 2018

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2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.
Dinakaran Murugesan, Peter C Ray, Tracy Bayliss, Gareth A Prosser, Justin R Harrison

ACS Infect Dis· June 2018

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Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi.
Linda J Herrera, Stephen Brand, Andres Santos, Lilian L Nohara, Justin Harrison

PLoS Negl Trop Dis· April 2016

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N-myristoyltransferase is a cell wall target in Aspergillus fumigatus.
Wenxia Fang, David A Robinson, Olawale G Raimi, David E Blair, Justin R Harrison

ACS Chem Biol· June 2015

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Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis.
Stephen Brand, Neil R Norcross, Stephen Thompson, Justin R Harrison, Victoria C Smith

J Med Chem· December 2014

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Give me strength or give me a reason: self-control, religion, and the currency of reputation.
Justin M D Harrison, Ryan McKay

Behav Brain Sci· December 2013

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A novel allosteric inhibitor of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei.
Michael D Urbaniak, Iain T Collie, Wenxia Fang, Tonia Aristotelous, Susanne Eskilsson, Justin Harrison

ACS Chem Biol· September 2013

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Development of real-time quantitative polymerase chain reaction assays to track treatment response in retinoid resistant acute promyelocytic leukemia.
Jelena V Jovanovic, Kristian Rennie, Dominic Culligan, Andrew Peniket, Anne Lennard, Justin Harrison

Front Oncol· August 2012

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Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.
Stephen Brand, Laura A T Cleghorn, Stuart P McElroy, David A Robinson, Victoria C Smith, Justin R Harrison

J Med Chem· January 2012

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Design, synthesis and biological evaluation of Trypanosoma brucei trypanothione synthetase inhibitors.
Daniel Spinks, Leah S Torrie, Stephen Thompson, Justin R Harrison, Julie A Frearson

ChemMedChem· January 2012

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Chemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasis.
Leah S Torrie, Susan Wyllie, Daniel Spinks, Sandra L Oza, Stephen Thompson, Justin R Harrison

J Biol Chem· December 2009

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Relapsed B-CLL/small B-lymphocytic lymphoma presenting as bronchiectasis.
Sunil Iyengar, Justin Harrison, Paul Richman

Eur J Haematol· September 2007

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A concise synthesis of the octalactins.
Paul T O'Sullivan, Wilm Buhr, Mary Ann M Fuhry, Justin R Harrison, John E Davies

J Am Chem Soc· February 2004

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Synthesis of sparteine-like chiral diamines and evaluation in the enantioselective lithiation-substitution of N-(tert-butoxycarbonyl)pyrrolidine.
Jean-Paul R Hermet, David W Porter, Michael J Dearden, Justin R Harrison, Tobias Koplin

Org Biomol Chem· November 2003

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Falsely elevated D-dimer results in a healthy patient on account of heterophiletul antibodies.
Chris Gardiner, Coralie Pennaneac'h, Ian J Mackie, Anne Sheldrake, Justin Harrison

Br J Haematol· September 2003

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