Publications by authors named "Ka Hing Che"

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canSAR: update to the cancer translational research and drug discovery knowledgebase.
Costas Mitsopoulos, Patrizio Di Micco, Eloy Villasclaras Fernandez, Daniela Dolciami, Esty Holt, Ka Hing Che

Nucleic Acids Res· January 2021

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A Chemical Probe for the ATAD2 Bromodomain.
Paul Bamborough, Chun-Wa Chung, Emmanuel H Demont, Rebecca C Furze, Andrew J Bannister, Ka Hing Che, Darren J Mitchell

Angew Chem Int Ed Engl· September 2016

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Advances and challenges in understanding histone demethylase biology.
Radoslaw P Nowak, Anthony Tumber, Catrine Johansson, Ka Hing Che, Paul Brennan

Curr Opin Chem Biol· August 2016

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Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
Natalie H Theodoulou, Paul Bamborough, Andrew J Bannister, Isabelle Becher, Rino A Bit, Ka Hing Che

J Med Chem· February 2016

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Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.
Sarah Picaud, Oleg Fedorov, Angeliki Thanasopoulou, Katharina Leonards, Katherine Jones, Ka Hing Che

Cancer Res· December 2015

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Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor.
Katherine S England, Anthony Tumber, Tobias Krojer, Giuseppe Scozzafava, Stanley S Ng, Michelle Daniel, KaHing Che

Medchemcomm· December 2014

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Kruidenier et al. reply.
Laurens Kruidenier, Chun-wa Chung, Zhongjun Cheng, John Liddle, KaHing Che, Marcus Bantscheff

Nature· October 2014

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The roles of Jumonji-type oxygenases in human disease.
Catrine Johansson, Anthony Tumber, KaHing Che, Peter Cain, Radosław Nowak

Epigenomics· February 2014

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5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.
Richard J Hopkinson, Anthony Tumber, Clarence Yapp, Rasheduzzaman Chowdhury, WeiShen Aik, Ka Hing Che

Chem Sci· August 2013

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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Laurens Kruidenier, Chun-wa Chung, Zhongjun Cheng, John Liddle, KaHing Che, Marcus Bantscheff

Nature· August 2012

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Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.
Nathan R Rose, Esther C Y Woon, Anthony Tumber, Louise J Walport, Rasheduzzaman Chowdhury, Ka Hing Che, Michelle Daniel

J Med Chem· July 2012

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Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases.
Esther C Y Woon, Anthony Tumber, Akane Kawamura, Lars Hillringhaus, Wei Ge, Ka Hing Che

Angew Chem Int Ed Engl· February 2012

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Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG.
Xiaohua Li, Liqiang He, Ka Hing Che, Sarah F Funderburk, Lifeng Pan

Nat Commun· February 2012

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A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases.
Xuelai Luo, Yongxiang Liu, Stefan Kubicek, Johanna Myllyharju, Anthony Tumber, Ka Hing Che

J Am Chem Soc· June 2011

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