Publications by authors named "Karin Toet"

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Improved Translational Relevance of In Vitro Fibrosis Models by Integrating IOX2-Mediated Hypoxia-Mimicking Pathways.
Manuel A González Hernández, Jennifer Venhorst, Lars Verschuren, Karin Toet, Martien P M Caspers

Biomedicines· June 2025

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Integrating text mining with network models for successful target identification: validation in MASH-induced liver fibrosis.
Jennifer Venhorst, Roeland Hanemaaijer, Remon Dulos, Martien P M Caspers, Karin Toet

Front Pharmacol· September 2024

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Butyrate Protects against Diet-Induced NASH and Liver Fibrosis and Suppresses Specific Non-Canonical TGF-β Signaling Pathways in Human Hepatic Stellate Cells.
Eveline Gart, Wim van Duyvenvoorde, Karin Toet, Martien P M Caspers, Lars Verschuren

Biomedicines· December 2021

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Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases.
Gustav Holmgren, Benjamin Ulfenborg, Annika Asplund, Karin Toet, Christian X Andersson

Int J Mol Sci· January 2020

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Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice.
Ramona A J Zwamborn, Roderick C Slieker, Petra C A Mulder, Inge Zoetemelk, Lars Verschuren, Karin H Toet

Sci Rep· March 2017

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Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice.
Martine C Morrison, Wen Liang, Petra Mulder, Lars Verschuren, Elsbet Pieterman, Karin Toet

J Hepatol· May 2015

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Differential effects of drug interventions and dietary lifestyle in developing type 2 diabetes and complications: a systems biology analysis in LDLr-/- mice.
Marijana Radonjic, Peter Y Wielinga, Suzan Wopereis, Thomas Kelder, Varshna S Goelela, Karin Toet

PLoS One· August 2013

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A dietary mixture containing fish oil, resveratrol, lycopene, catechins, and vitamins E and C reduces atherosclerosis in transgenic mice.
Lars Verschuren, Peter Y Wielinga, Wim van Duyvenvoorde, Samira Tijani, Karin Toet

J Nutr· May 2011

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Anti-inflammatory salicylate beneficially modulates pre-existing atherosclerosis through quenching of NF-κB activity and lowering of cholesterol.
Jitske de Vries-van der Weij, Karin Toet, Susanne Zadelaar, Peter Y Wielinga, Robert Kleemann

Atherosclerosis· November 2010

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Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance.
Robert Kleemann, Marjan van Erk, Lars Verschuren, Anita M van den Hoek, Maud Koek, Karin Toet

PLoS One· January 2010

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Human CETP aggravates atherosclerosis by increasing VLDL-cholesterol rather than by decreasing HDL-cholesterol in APOE*3-Leiden mice.
Jitske de Vries-van der Weij, Susanne Zadelaar, Karin Toet, Louis M Havekes, Teake Kooistra

Atherosclerosis· September 2009

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Leptin and the proinflammatory state associated with human obesity.
Chris J Hukshorn, Jan H N Lindeman, Karin H Toet, Wim H M Saris, Paul H C Eilers

J Clin Endocrinol Metab· April 2004

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Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-alpha-activated human peritoneal mesothelial cells.
Bettina Haslinger, Robert Kleemann, Karin H Toet, Teake Kooistra

Kidney Int· June 2003

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Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol lowering.
Bettina Haslinger, Martin F Goedde, Karin H Toet, Teake Kooistra

Kidney Int· November 2002

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