Publications by authors named "Jennifer Venhorst"

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Improved Translational Relevance of In Vitro Fibrosis Models by Integrating IOX2-Mediated Hypoxia-Mimicking Pathways.
Manuel A González Hernández, Jennifer Venhorst, Lars Verschuren, Karin Toet, Martien P M Caspers

Biomedicines· June 2025

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Drug target assessments: classifying target modulation and associated health effects using multi-level BERT-based classification models.
Jennifer Venhorst, Gino Kalkman

Bioinform Adv· March 2025

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Identifying patient subgroups in MASLD and MASH-associated fibrosis: molecular profiles and implications for drug development.
Manuel A González Hernández, Lars Verschuren, Martien P M Caspers, Martine C Morrison, Jennifer Venhorst

Sci Rep· October 2024

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Integrating text mining with network models for successful target identification: validation in MASH-induced liver fibrosis.
Jennifer Venhorst, Roeland Hanemaaijer, Remon Dulos, Martien P M Caspers, Karin Toet

Front Pharmacol· September 2024

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Oncostatin M: Risks and Benefits of a Novel Therapeutic Target for Atherosclerosis.
Tanja Rouhani Rankouhi, Daniëlle van Keulen, Dennie Tempel, Jennifer Venhorst

Curr Drug Targets· November 2022

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Battling Enteropathogenic Clostridia: Phage Therapy for and .
Jennifer Venhorst, Jos M B M van der Vossen, Valeria Agamennone

Front Microbiol· June 2022

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Optimization of N'-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT6 antagonistic binding pocket.
Arnold van Loevezijn, Jennifer Venhorst, Wouter I Iwema Bakker, Jos H M Lange, Wouter de Looff

Bioorg Med Chem Lett· March 2016

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Target-drug interactions: first principles and their application to drug discovery.
Sara Núñez, Jennifer Venhorst, Chris G Kruse

Drug Discov Today· January 2012

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N'-(arylsulfonyl)pyrazoline-1-carboxamidines as novel, neutral 5-hydroxytryptamine 6 receptor (5-HT₆R) antagonists with unique structural features.
Arnold van Loevezijn, Jennifer Venhorst, Wouter I Iwema Bakker, Cor G de Korte, Wouter de Looff

J Med Chem· October 2011

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Biophysical and physicochemical methods differentiate highly ligand-efficient human D-amino acid oxidase inhibitors.
Jos H M Lange, Jennifer Venhorst, Maria J P van Dongen, Jurjen Frankena, Firas Bassissi

Eur J Med Chem· October 2011

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Design of a high fragment efficiency library by molecular graph theory.
Jennifer Venhorst, Sara Núñez, Chris G Kruse

ACS Med Chem Lett· December 2010

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Assessment of a novel scoring method based on solvent accessible surface area descriptors.
Sara Núñez, Jennifer Venhorst, Chris G Kruse

J Chem Inf Model· April 2010

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Assessment of scaffold hopping efficiency by use of molecular interaction fingerprints.
Jennifer Venhorst, Sara Núñez, Jan Willem Terpstra, Chris G Kruse

J Med Chem· June 2008

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Modeling and molecular dynamics of glutamine transaminase K/cysteine conjugate beta-lyase.
Jennifer Venhorst, Antonius M ter Laak, Moira Meijer, Ineke van de Wetering, Jan N M Commandeur

J Mol Graph Model· September 2003

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Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities.
Jennifer Venhorst, Antonius M ter Laak, Jan N M Commandeur, Yoshihiko Funae, Toyoko Hiroi

J Med Chem· January 2003

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