Publications by authors named "Keith A Strand"

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Design of Potent Menin-KMT2A Interaction Inhibitors with Improved ADME Properties and Reduced hERG Affinity.
Bruno D Chapsal, Jennifer R Kimbrough, Stephanie M Bester, Alex Bergstrom, Donald S Backos, Keith A Strand

ACS Med Chem Lett· February 2025

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KLF4 in smooth muscle cell-derived progenitor cells is essential for angiotensin II-induced cardiac inflammation and fibrosis.
Sizhao Lu, Austin J Jolly, Allison M Dubner, Keith A Strand, Marie F Mutryn

bioRxiv· June 2024

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Smooth muscle-derived adventitial progenitor cells direct atherosclerotic plaque composition complexity in a Klf4-dependent manner.
Allison M Dubner, Sizhao Lu, Austin J Jolly, Keith A Strand, Marie F Mutryn

JCI Insight· November 2023

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Smooth muscle-derived adventitial progenitor cells promote key cell type transitions controlling plaque stability in atherosclerosis in a Klf4-dependent manner.
Allison M Dubner, Sizhao Lu, Austin J Jolly, Keith A Strand, Marie F Mutryn

bioRxiv· July 2023

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Redistribution of the chromatin remodeler Brg1 directs smooth muscle-derived adventitial progenitor-to-myofibroblast differentiation and vascular fibrosis.
Austin J Jolly, Sizhao Lu, Allison M Dubner, Keith A Strand, Marie F Mutryn

JCI Insight· May 2023

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Heterogeneous subpopulations of adventitial progenitor cells regulate vascular homeostasis and pathological vascular remodelling.
Austin J Jolly, Sizhao Lu, Keith A Strand, Allison M Dubner, Marie F Mutryn

Cardiovasc Res· May 2022

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Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis.
Sizhao Lu, Austin J Jolly, Keith A Strand, Allison M Dubner, Marie F Mutryn

JCI Insight· December 2020

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High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling.
Keith A Strand, Sizhao Lu, Marie F Mutryn, Linfeng Li, Qiong Zhou

Arterioscler Thromb Vasc Biol· August 2020

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PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report.
Sizhao Lu, Keith A Strand, Marie F Mutryn, Rebecca M Tucker, Austin J Jolly

Arterioscler Thromb Vasc Biol· February 2020

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Repeated Morphine Prolongs Postoperative Pain in Male Rats.
Peter M Grace, Erika L Galer, Keith A Strand, Kaci Corrigan, Debra Berkelhammer

Anesth Analg· January 2019

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Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats.
Peter M Grace, Keith A Strand, Erika L Galer, Kenner C Rice, Steven F Maier

Brain Behav Immun· August 2018

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MicroRNA-124 and microRNA-146a both attenuate persistent neuropathic pain induced by morphine in male rats.
Peter M Grace, Keith A Strand, Erika L Galer, Steven F Maier, Linda R Watkins

Brain Res· August 2018

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DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats.
Peter M Grace, Xiaohui Wang, Keith A Strand, Michael V Baratta, Yingning Zhang

Exp Neurol· June 2018

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Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy.
Peter M Grace, Lisa C Loram, John P Christianson, Keith A Strand, Johanna G Flyer-Adams

Brain Behav Immun· January 2017

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Prior voluntary wheel running attenuates neuropathic pain.
Peter M Grace, Timothy J Fabisiak, Suzanne M Green-Fulgham, Nathan D Anderson, Keith A Strand

Pain· September 2016

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Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation.
Peter M Grace, Keith A Strand, Erika L Galer, Daniel J Urban, Xiaohui Wang

Proc Natl Acad Sci U S A· June 2016

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(+)-Naltrexone is neuroprotective and promotes alternative activation in the mouse hippocampus after cardiac arrest/cardiopulmonary resuscitation.
Peter M Grace, Kaori Shimizu, Keith A Strand, Kenner C Rice, Guiying Deng

Brain Behav Immun· August 2015

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Adenosine 2A receptor agonism: A single intrathecal administration attenuates motor paralysis in experimental autoimmune encephalopathy in rats.
Lisa C Loram, Keith A Strand, Frederick R Taylor, Evan Sloane, Anne-Marie Van Dam

Brain Behav Immun· May 2015

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Suppression of voluntary wheel running in rats is dependent on the site of inflammation: evidence for voluntary running as a measure of hind paw-evoked pain.
Peter M Grace, Keith A Strand, Steven F Maier, Linda R Watkins

J Pain· February 2014

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Intrathecal injection of adenosine 2A receptor agonists reversed neuropathic allodynia through protein kinase (PK)A/PKC signaling.
Lisa C Loram, Frederick R Taylor, Keith A Strand, Jacqueline A Harrison, Rachael Rzasalynn

Brain Behav Immun· October 2013

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Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain.
Xiaohui Wang, Peter M Grace, Michael N Pham, Kui Cheng, Keith A Strand

FASEB J· July 2013

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Systemic administration of an alpha-7 nicotinic acetylcholine agonist reverses neuropathic pain in male Sprague Dawley rats.
Lisa C Loram, Frederick R Taylor, Keith A Strand, Steven F Maier, Jason D Speake

J Pain· December 2012

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Prior exposure to repeated morphine potentiates mechanical allodynia induced by peripheral inflammation and neuropathy.
Lisa C Loram, Peter M Grace, Keith A Strand, Frederick R Taylor, Amanda Ellis

Brain Behav Immun· November 2012

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Sex and estradiol influence glial pro-inflammatory responses to lipopolysaccharide in rats.
Lisa C Loram, Paige W Sholar, Frederick R Taylor, Julie L Wiesler, Jessica A Babb, Keith A Strand

Psychoneuroendocrinology· October 2012

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Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors.
Leah E Hains, Lisa C Loram, Frederick R Taylor, Keith A Strand, Julie L Wieseler

J Neuroimmunol· October 2011

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