Publications by authors named "Keith Knutson"

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A phase II trial to evaluate the safety and immunogenicity of two doses of a folate receptor alpha vaccine in patients with triple negative breast cancer.
Keith L Knutson, Hala Abu-Fares, Patricia Keating, Matthew S Block, Nadine Norton

Clin Cancer Res· November 2025

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A vaccination strategy to prevent coxsackie virus B3-induced development of pancreatic cancer.
Veethika Pandey, Heike R Döppler, Ligia I Bastea, Alicia K Fleming Martinez, Barath Shreeder, Keith L Knutson

JCI Insight· September 2025

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Pembrolizumab in Combination with Binimetinib in Patients with Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer.
Saranya Chumsri, Joseph J Larson, Emily Liu, Kathleen S Tenner, Daniel Adams, Keith L Knutson

Clin Cancer Res· May 2025

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T-cell immune cluster analysis using CyTOF identifies unique subgroups of patients with acute myeloid leukemia.
Talha Badar, Keith L Knutson, James Foran, Naseema Gangat, Kevin D Pavelko

Blood Adv· January 2025

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BRAFV600E/pTERT double mutated papillary thyroid cancers exhibit immune gene suppression.
Ana-Maria Sigarteu Chindris, Michael Rivera, Yaohua Ma, Asha Nair, Yi Liu, Keith L Knutson

Front Endocrinol (Lausanne)· December 2024

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Vaccination with folate receptor-alpha peptides in patients with ovarian cancer following response to platinum-based therapy: A randomized, multicenter clinical trial.
Aditi Gupta, Roisin E O'Cearbhaill, Matthew S Block, Erika Hamilton, Jason A Konner, Keith L Knutson

Gynecol Oncol· October 2024

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Molecular markers of proliferation, DNA repair, and immune infiltration defines high-risk subset of resectable retroperitoneal sarcomas.
Nathan D Seligson, Yan W Asmann, Tariq Almerey, Yaquelin Coll Zayas, Mark A Edgar, Keith L Knutson

Surg Oncol· October 2024

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Expression of c-erb-B2 oncoprotein as a neoantigen strategy to repurpose anti-neu antibody therapy in a model of melanoma.
Emmanuel M Gabriel, Brian Necela, Deborah Bahr, Sneha Vivekanandhan, Barath Shreeder, Keith L Knutson

Sci Rep· October 2024

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Pre-treatment peripheral blood immunophenotyping and response to neoadjuvant chemotherapy in operable breast cancer.
Roberto A Leon-Ferre, Kaitlyn R Whitaker, Vera J Suman, Tanya Hoskin, Karthik V Giridhar, Keith L Knutson

Breast Cancer Res· June 2024

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Regulation of Tumor Dendritic Cells by Programmed Cell Death 1 Pathways.
Keith L Knutson

J Immunol· May 2024

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Comprehensive profiling of cancer neoantigens from aberrant RNA splicing.
Daniel P Wickland, Colton McNinch, Erik Jessen, Brian Necela, Barath Shreeder, Keith L Knutson

J Immunother Cancer· May 2024

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Higher and Sustained Cell-Mediated Immune Responses After 3 Doses of mRNA COVID-19 Vaccine in Patients With Inflammatory Bowel Disease on Anti-Tumor Necrosis Factor Therapy.
Freddy Caldera, Stacey Rolak, Francis A Farraye, Brian M Necela, Davitte Cogen, Keith L Knutson

Clin Transl Gastroenterol· April 2024

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Human tumour vessel heterogeneity in ovarian cancer and its association with response to neoadjuvant chemotherapy.
Emmanuel M Gabriel, Kulkaew Sukniam, Kyle Popp, Gabrielle Kowkabany, Harsheen K Manaise, Keith L Knutson

Clin Transl Med· April 2024

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Expression of c-erb-B2 oncoprotein as a neoantigen strategy to repurpose anti-neu antibody therapy in a model of melanoma.
Emmanuel M Gabriel, Brian Necela, Deborah Bahr, Sneha Vivekanandhan, Barath Shreeder, Keith L Knutson

Res Sq· April 2024

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Th17-inducing dendritic cell vaccines stimulate effective CD4 T cell-dependent antitumor immunity in ovarian cancer that overcomes resistance to immune checkpoint blockade.
Yan Luo, Barath Shreeder, James W Jenkins, Huashan Shi, Purushottam Lamichhane, Keith L Knutson

J Immunother Cancer· November 2023

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Higher Cell-Mediated Immune Responses in Patients With Inflammatory Bowel Disease on Anti-TNF Therapy After COVID-19 Vaccination.
Freddy Caldera, Francis A Farraye, Brian M Necela, Davitte Cogen, Sumona Saha, Keith L Knutson

Inflamm Bowel Dis· August 2023

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Immune responses and disease biomarker long-term changes following COVID-19 mRNA vaccination in a cohort of rheumatic disease patients.
Zesheng An, Gabriel Figueroa-Parra, Xian Zhou, Yanfeng Li, Jane Jaquith, Keith L Knutson

Front Immunol· August 2023

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Distinct spatial immune microlandscapes are independently associated with outcomes in triple-negative breast cancer.
Jodi M Carter, Saranya Chumsri, Douglas A Hinerfeld, Yaohua Ma, Xue Wang, Keith L Knutson

Nat Commun· April 2023

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Immune responses and disease biomarker long-term changes following COVID-19 mRNA vaccination in a cohort of rheumatic disease patients.
Zesheng An, Xian Zhou, Yanfeng Li, Jane Jaquith, Kathleen McCarthy-Fruin, Keith L Knutson

medRxiv· March 2023

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Immune cells are increased in normal breast tissues of BRCA1/2 mutation carriers.
Joshua Ogony, Tanya L Hoskin, Melody Stallings-Mann, Stacey Winham, Rushin Brahmbhatt, Keith L Knutson

Breast Cancer Res Treat· January 2023

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Protein kinase Cι mediates immunosuppression in lung adenocarcinoma.
Ning Yin, Yi Liu, Capella Weems, Barath Shreeder, Yanyan Lou, Keith L Knutson

Sci Transl Med· November 2022

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Resistance to Trastuzumab.
Sneha Vivekanandhan, Keith L Knutson

Cancers (Basel)· October 2022

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APOBEC Mutational Signatures in Hormone Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative Breast Cancers Are Associated With Poor Outcomes on CDK4/6 Inhibitors and Endocrine Therapy.
Sarah Sammons, Kira Raskina, Natalie Danziger, Laura Alder, Alexa B Schrock, Keith L Knutson

JCO Precis Oncol· October 2022

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Characterization of Platelet Biologic Markers in the Early Pathogenesis of Postoperative Acute Respiratory Distress Syndrome.
Hemang Yadav, Laurie A Meade, Rickey E Carter, Keith Knutson, Ognjen Gajic

Crit Care Explor· July 2022

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Adaptive immune signature in HER2-positive breast cancer in NCCTG (Alliance) N9831 and NeoALTTO trials.
Saranya Chumsri, Zhuo Li, Daniel J Serie, Nadine Norton, Afshin Mashadi-Hossein, Keith L Knutson

NPJ Breast Cancer· May 2022

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