Publications by authors named "Kevin Bugge"

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CRISPR-Cas9-based treatment of myocilin-associated glaucoma.
Ankur Jain, Gulab Zode, Ramesh B Kasetti, Fei A Ran, Winston Yan, Kevin Bugge

Proc Natl Acad Sci U S A· October 2017

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Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma.
Gulab S Zode, Markus H Kuehn, Darryl Y Nishimura, Charles C Searby, Kabhilan Mohan, Kevin Bugge

J Clin Invest· August 2015

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Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma.
Gulab S Zode, Arti B Sharma, Xiaolei Lin, Charles C Searby, Kevin Bugge

J Clin Invest· May 2014

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BBS mutations modify phenotypic expression of CEP290-related ciliopathies.
Yan Zhang, Seongjin Seo, Sajag Bhattarai, Kevin Bugge, Charles C Searby

Hum Mol Genet· January 2014

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Ectopic expression of human BBS4 can rescue Bardet-Biedl syndrome phenotypes in Bbs4 null mice.
Xitiz Chamling, Seongjin Seo, Kevin Bugge, Charles Searby, Deng F Guo

PLoS One· October 2013

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BBS7 is required for BBSome formation and its absence in mice results in Bardet-Biedl syndrome phenotypes and selective abnormalities in membrane protein trafficking.
Qihong Zhang, Darryl Nishimura, Tim Vogel, Jianqiang Shao, Ruth Swiderski, Kevin Bugge

J Cell Sci· June 2013

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Abnormal development of NG2+PDGFR-α+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model.
Calvin S Carter, Timothy W Vogel, Qihong Zhang, Seongjin Seo, Ruth E Swiderski, Kevin Bugge

Nat Med· December 2012

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Structural defects in cilia of the choroid plexus, subfornical organ and ventricular ependyma are associated with ventriculomegaly.
Ruth E Swiderski, Khristofor Agassandian, Jean L Ross, Kevin Bugge, Martin D Cassell

Fluids Barriers CNS· October 2012

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BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes.
Qihong Zhang, Seongjin Seo, Kevin Bugge, Edwin M Stone, Val C Sheffield

Hum Mol Genet· May 2012

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Topical ocular sodium 4-phenylbutyrate rescues glaucoma in a myocilin mouse model of primary open-angle glaucoma.
Gulab S Zode, Kevin E Bugge, Kabhilan Mohan, Sinisa D Grozdanic, Joseph C Peters

Invest Ophthalmol Vis Sci· March 2012

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Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes.
Qihong Zhang, Darryl Nishimura, Seongjin Seo, Tim Vogel, Donald A Morgan, Kevin Bugge

Proc Natl Acad Sci U S A· December 2011

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A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened.
Seongjin Seo, Qihong Zhang, Kevin Bugge, David K Breslow, Charles C Searby

PLoS Genet· November 2011

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Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma.
Gulab S Zode, Markus H Kuehn, Darryl Y Nishimura, Charles C Searby, Kabhilan Mohan, Kevin Bugge

J Clin Invest· September 2011

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Identification and functional analysis of the vision-specific BBS3 (ARL6) long isoform.
Pamela R Pretorius, Lisa M Baye, Darryl Y Nishimura, Charles C Searby, Kevin Bugge

PLoS Genet· March 2010

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling.
Seongjin Seo, Deng-Fu Guo, Kevin Bugge, Donald A Morgan, Kamal Rahmouni

Hum Mol Genet· April 2009

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Loss of Bardet-Biedl syndrome proteins alters the morphology and function of motile cilia in airway epithelia.
Alok S Shah, Sara L Farmen, Thomas O Moninger, Thomas R Businga, Michael P Andrews, Kevin Bugge

Proc Natl Acad Sci U S A· March 2008

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Evaluation of complex inheritance involving the most common Bardet-Biedl syndrome locus (BBS1).
Kirk Mykytyn, Darryl Y Nishimura, Charles C Searby, Gretel Beck, Kevin Bugge

Am J Hum Genet· February 2003

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