Publications by authors named "Kevin Lindquist"

Claim this Profile
O
One size does not fit all: navigating the multi-dimensional space to optimize T-cell engaging protein therapeutics.
Wei Chen, Fan Yang, Carole Wang, Jatin Narula, Edward Pascua, Kevin C Lindquist

MAbs· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity.
Yuanming Xu, Lucia Campos Carrascosa, Yik Andy Yeung, Matthew Ling-Hon Chu, Wenjing Yang, Kevin C Lindquist

Cancer Immunol Res· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex.
Weifeng Liu, Zachary Maben, Carole Wang, Kevin C Lindquist, Manqing Li

J Biol Chem· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes antitumor immunity.
Shih-Hsun Chen, Pawel K Dominik, Jessica Stanfield, Sheng Ding, Wenjing Yang, Kevin C Lindquist

J Immunother Cancer· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Direct control of CAR T cells through small molecule-regulated antibodies.
Spencer Park, Edward Pascua, Kevin C Lindquist, Christopher Kimberlin, Xiaodi Deng

Nat Commun· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An Optimized Full-Length FLT3/CD3 Bispecific Antibody Demonstrates Potent Anti-leukemia Activity and Reversible Hematological Toxicity.
Yik Andy Yeung, Veena Krishnamoorthy, Danielle Dettling, Cesar Sommer, Kris Poulsen, Kevin Lindquist

Mol Ther· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preclinical Efficacy and Safety Comparison of CD3 Bispecific and ADC Modalities Targeting BCMA for the Treatment of Multiple Myeloma.
Siler H Panowski, Tracy C Kuo, Yi Zhang, Amy Chen, Tao Geng, Kevin C Lindquist

Mol Cancer Ther· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Author Correction: Targeting CLDN18.2 by CD3 Bispecific and ADC Modalities for the Treatments of Gastric and Pancreatic Cancer.
Guoyun Zhu, Davide Foletti, Xiaohui Liu, Sheng Ding, Jody Melton Witt, Kevin C Lindquist

Sci Rep· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting CLDN18.2 by CD3 Bispecific and ADC Modalities for the Treatments of Gastric and Pancreatic Cancer.
Guoyun Zhu, Davide Foletti, Xiaohui Liu, Sheng Ding, Jody Melton Witt, Kevin C Lindquist

Sci Rep· June 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Ligand-Blocking and Membrane-Proximal Domain Targeting Anti-OX40 Antibodies Mediate Potent T Cell-Stimulatory and Anti-Tumor Activity.
Pamela Zhang, Guang Huan Tu, Jie Wei, Pamela Santiago, Lance R Larrabee, Kevin Lindquist

Cell Rep· June 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates.
Maria José Costa, Jyothirmayee Kudaravalli, Jing-Tyan Ma, Wei-Hsien Ho, Kathy Delaria, Kevin Lindquist

Sci Rep· February 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Productive common light chain libraries yield diverse panels of high affinity bispecific antibodies.
Thomas Van Blarcom, Kevin Lindquist, Zea Melton, Wai Ling Cheung, Chris Wagstrom

MAbs· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab.
S Michael Chin, Christopher R Kimberlin, Zygy Roe-Zurz, Pamela Zhang, Allison Xu, Kevin Lindquist

Nat Commun· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models.
Oi Kwan Wong, Thomas-Toan Tran, Wei-Hsien Ho, Meritxell Galindo Casas, Melinda Au, Kevin C Lindquist

Oncotarget· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies.
Shu-Hui Liu, Yin Gu, Bernadette Pascual, Zhengming Yan, Max Hallin, Kevin Lindquist

Blood Adv· June 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia.
Manoj K Kashyap, Carlos I Amaya-Chanaga, Deepak Kumar, Brett Simmons, Nanni Huser, Kevin Lindquist

J Hematol Oncol· May 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire.
Yik Andy Yeung, Davide Foletti, Xiaodi Deng, Yasmina Abdiche, Pavel Strop, Kevin Lindquist

Nat Commun· November 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity.
Yasmina Noubia Abdiche, Yik Andy Yeung, Javier Chaparro-Riggers, Ishita Barman, Pavel Strop, Kevin Lindquist

MAbs· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading.
Pavel Strop, Kathy Delaria, Davide Foletti, Jody Melton Witt, Adela Hasa-Moreno, Kevin C Lindquist

Nat Biotechnol· July 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
Sherry L La Porte, Charles Eigenbrot, Mark Ultsch, Wei-Hsien Ho, Davide Foletti, Kevin C Lindquist

MAbs· February 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH region.
Michael J Osborn, Biao Ma, Suzanne Avis, Ashleigh Binnie, Jeanette Dilley, Kevin Lindquist

J Immunol· February 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exploring the dynamic range of the kinetic exclusion assay in characterizing antigen-antibody interactions.
Christine Bee, Yasmina N Abdiche, Donna M Stone, Sierra Collier, Kevin C Lindquist

PLoS One· September 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Label-free epitope binning assays of monoclonal antibodies enable the identification of antigen heterogeneity.
Yasmina N Abdiche, Kevin C Lindquist, Donna M Stone, Arvind Rajpal, Jaume Pons

J Immunol Methods· August 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair.
Pavel Strop, Wei-Hsien Ho, Leila M Boustany, Yasmina N Abdiche, Kevin C Lindquist

J Mol Biol· July 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Increasing serum half-life and extending cholesterol lowering in vivo by engineering antibody with pH-sensitive binding to PCSK9.
Javier Chaparro-Riggers, Hong Liang, Rachel M DeVay, Lanfang Bai, Janette E Sutton, Kevin Lindquist

J Biol Chem· March 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis