Publications by authors named "Kevin Saunders"

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An integrated workflow for structural virology with a 100 keV electron microscope.
Rasangi Pathirage, Moumita Dutta, Ruth J Parsons, Muralikrishna Lella, Emma Atwood, Kevin O Saunders

bioRxiv· December 2025

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Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Wilton B Williams, S Munir Alam, Gilad Ofek, Nathaniel Erdmann, David C Montefiori, Kevin O Saunders

Cell· November 2025

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Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies.
Ryan S Roark, Rumi Habib, Jason Gorman, Hui Li, Andrew Jesse Connell, Kevin O Saunders

J Exp Med· October 2025

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Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development.
Rumi Habib, Ryan S Roark, Hui Li, Andrew Jesse Connell, Michael P Hogarty, Kevin O Saunders

bioRxiv· September 2025

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Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody.
Qingbo Liu, Ruth J Parsons, Kevin Wiehe, Robert J Edwards, Kevin O Saunders

Structure· August 2025

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Design of SARS-CoV-2 RBD immunogens to focus immune responses toward conserved coronavirus epitopes.
Caitlin Harris, A Brenda Kapingidza, James E San, Jayani Christopher, Tyler Gavitt, Kevin O Saunders

J Virol· July 2025

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Nonstabilized SARS-CoV-2 spike mRNA vaccination induces broadly neutralizing antibodies in nonhuman primates.
R Dilshan Malewana, Victoria Stalls, Aaron May, Xiaozhi Lu, David R Martinez, Kevin O Saunders

Sci Transl Med· June 2025

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Convergence and divergence of B cell responses in two HIV-1 Env immunizations in Rhesus macaques.
Jenna M DeLuca, Maria Blasi, Taylor J McGee, Shalini Jha, Xiaoying Shen, Kevin O Saunders

Commun Med (Lond)· May 2025

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Status of HIV vaccine development: progress and promise.
Barton F Haynes, Kevin O Saunders, Beatrice H Hahn, Kevin Wiehe, Lindsey R Baden

J Int AIDS Soc· May 2025

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A neutralizing human antibody induces movement of the HCoV-229E receptor binding domain.
Mera F Liccione, Trevor Scobey, Heather M Froggatt, Camryn Pajon, Boyd L Yount, Kevin O Saunders

bioRxiv· May 2025

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Structural and antigenic characterization of novel and diverse Henipavirus glycoproteins.
Aaron J May, Muralikrishna Lella, Jared Lindenberger, Alex Berkman, Ujjwal Kumar, Kevin O'Neil Saunders

bioRxiv· April 2025

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Guideline Directed Anticoagulant Treatment and Dosing in a Contemporary Atrial Fibrillation Cohort: Analysis of the TRANSECT-AF Program.
Cole Clifford, Shaun G Goodman, Mary K Tan, Jean Gregoire, Jeffrey Habert, Kevin Saunders

CJC Open· April 2025

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An engineered immunogen activates diverse HIV broadly neutralizing antibody precursors and promotes acquisition of improbable mutations.
Olivia M Swanson, Qianyi E Zhang, Elizabeth Van Itallie, Ming Tian, Alecia R Brown, Kevin O Saunders

Sci Transl Med· January 2025

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Design of SARS-CoV-2 RBD Immunogens to Focus Immune Responses Towards Conserved Coronavirus Epitopes.
Caitlin Harris, A Brenda Kapingidza, James E San, Jayani Christopher, Tyler Gavitt, Kevin O Saunders

bioRxiv· January 2025

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Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies.
Rory Henderson, Kara Anasti, Kartik Manne, Victoria Stalls, Carrie Saunders, Kevin O Saunders

Nat Commun· November 2024

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Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques.
Sommer Holmes, Hui Li, Xiaoying Shen, Mitchell Martin, Ryan Tuck, Kevin O Saunders

Nat Commun· November 2024

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Anti-HIV-1 B cell antigen receptor signaling and structure.
Bhishem Thakur, Jahangir Alam, Kenneth Cronin, Parth Patel, Kara Anasti, Kevin Saunders

bioRxiv· November 2024

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Comparison of the immunogenicity of mRNA-encoded and protein HIV-1 Env-ferritin nanoparticle designs.
Zekun Mu, Jill Whitley, Diana Martik, Laura Sutherland, Amanda Newman, Kevin O Saunders

J Virol· September 2024

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Isolation and characterization of IgG3 glycan-targeting antibodies with exceptional cross-reactivity for diverse viral families.
Matthew J Vukovich, Andrea R Shiakolas, Jared Lindenberger, Robert A Richardson, Lindsay E Bass, Kevin O Saunders

PLoS Pathog· September 2024

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Safety and immunogenicity after a 30-month boost of a subtype C ALVAC-HIV (vCP2438) vaccine prime plus bivalent subtype C gp120/MF59 vaccine boost (HVTN 100): A phase 1-2 randomized double-blind placebo-controlled trial.
Vimla Naicker, Fatima Laher, Linda-Gail Bekker, Kelly E Seaton, Mary Allen, Kevin Saunders

PLOS Glob Public Health· September 2024

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SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition.
Qianyi E Zhang, Jared Lindenberger, Ruth J Parsons, Bhishem Thakur, Rob Parks, Kevin O Saunders

Mol Cell· July 2024

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Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Wilton B Williams, S Munir Alam, Gilad Ofek, Nathaniel Erdmann, David C Montefiori, Kevin O Saunders

Cell· June 2024

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Non-neutralizing SARS-CoV-2 N-terminal domain antibodies protect mice against severe disease using Fc-mediated effector functions.
Camille N Pierre, Lily E Adams, Jaclyn S Higgins, Kara Anasti, Derrick Goodman, Kevin O Saunders

PLoS Pathog· June 2024

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HIV-1 neutralizing antibodies in SHIV-infected macaques recapitulate structurally divergent modes of human V2 apex recognition with a single D gene.
Ryan S Roark, Rumi Habib, Jason Gorman, Hui Li, Andrew Jesse Connell, Kevin O Saunders

bioRxiv· June 2024

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Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction.
Kevin Wiehe, Kevin O Saunders, Victoria Stalls, Derek W Cain, Sravani Venkatayogi

Cell Host Microbe· May 2024

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