Publications by authors named "Kjell Johnson"

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What they forgot to tell you about machine learning with an application to pharmaceutical manufacturing.
Kjell Johnson, Max Kuhn

Pharm Stat· April 2025

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Analysis of chemometric models applied to Raman spectroscopy for monitoring key metabolites of cell culture.
Carl Rafferty, Kjell Johnson, Jim O'Mahony, Barbara Burgoyne, Rosemary Rea

Biotechnol Prog· July 2020

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Automated plaque analysis for the prognostication of major adverse cardiac events.
Marly van Assen, Akos Varga-Szemes, U Joseph Schoepf, Taylor M Duguay, H Todd Hudson, Kjell Johnson

Eur J Radiol· July 2019

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Validation of Sysmex XT-2000iV analyzer-generated quantitative bone marrow differential counts in cynomolgus monkeys, Beagle dogs, and CD-1 mice.
Kay A Criswell, Jeffrey H Bock, Kjell Johnson, Ryan A Criswell, Richard P Giovanelli

Vet Clin Pathol· December 2018

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Multivariate analysis of cytokine profiles in pregnancy complications.
Fawaz Azizieh, Kamaludin Dingle, Raj Raghupathy, Kjell Johnson, Jacob VanderPlas

Am J Reprod Immunol· March 2018

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Identification of novel biomarkers to monitor β-cell function and enable early detection of type 2 diabetes risk.
Kirstine J Belongie, Ele Ferrannini, Kjell Johnson, Patricia Andrade-Gordon, Michael K Hansen

PLoS One· October 2017

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Novel Methods for Prioritizing "Close-In" Analogs from Structure-Activity Relationship Matrices.
Liying Zhang, Kjell Johnson, Jeremy Starr, Jared Milbank, Andrew M Kuhn

J Chem Inf Model· July 2017

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Predictive Modeling of Response to Pregabalin for the Treatment of Neuropathic Pain Using 6-Week Observational Data: A Spectrum of Modern Analytics Applications.
Birol Emir, Kjell Johnson, Max Kuhn, Bruce Parsons

Clin Ther· January 2017

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Lost in translation: The search for an in vitro screen for spermatogenic toxicity.
Robert E Chapin, Timothy Winton, William Nowland, Nichole Danis, Steven Kumpf, Kjell Johnson

Birth Defects Res B Dev Reprod Toxicol· December 2016

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Development of a squamous cell carcinoma mouse model for immunotoxicity testing.
Devon D Sominski, Patricia Rafferty, Kerry Brosnan, Amy Volk, Mindi Walker, Kjell Johnson

J Immunotoxicol· September 2016

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STEP levels are unchanged in pre-frontal cortex and associative striatum in post-mortem human brain samples from subjects with schizophrenia, bipolar disorder and major depressive disorder.
Thomas A Lanz, J Julie Joshi, Veronica Reinhart, Kjell Johnson, Lonnie E Grantham

PLoS One· February 2016

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Inter-Method Performance Study of Tumor Volumetry Assessment on Computed Tomography Test-Retest Data.
Andrew J Buckler, Jovanna Danagoulian, Kjell Johnson, Adele Peskin, Marios A Gavrielides

Acad Radiol· November 2015

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Three-dimensional lung tumor microenvironment modulates therapeutic compound responsiveness in vitro--implication for drug development.
Jason E Ekert, Kjell Johnson, Brandy Strake, Jose Pardinas, Stephen Jarantow

PLoS One· November 2014

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Validation of Sysmex XT-2000iV generated quantitative bone marrow differential counts in untreated Wistar rats.
Kay A Criswell, Jeffrey H Bock, Samantha E Wildeboer, Kjell Johnson, Richard P Giovanelli

Vet Clin Pathol· June 2014

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Comparison of the Sysmex XT-2000iV and microscopic bone marrow differential counts in Wistar rats treated with cyclophosphamide, erythropoietin, or serial phlebotomy.
Kay A Criswell, Jeffrey H Bock, Samantha E Wildeboer, Kjell Johnson, Richard P Giovanelli

Vet Clin Pathol· June 2014

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The inhibin B response in male rats treated with two drug candidates.
Robert E Chapin, James D Alvey, Richard A Goldstein, Melba G Dokmanovich, William J Reagan, Kjell Johnson

Birth Defects Res B Dev Reprod Toxicol· February 2013

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Multinomial modeling and an evaluation of common data-mining algorithms for identifying signals of disproportionate reporting in pharmacovigilance databases.
Kjell Johnson, Cen Guo, Mark Gosink, Vicky Wang, Manfred Hauben

Bioinformatics· December 2012

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Statistical analysis and compound selection of combinatorial libraries for soluble epoxide hydrolase.
Li Xing, Robert Goulet, Kjell Johnson

J Chem Inf Model· July 2011

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Not a walk in the park: the ECVAM whole embryo culture model challenged with pharmaceuticals and attempted improvements with random forest design.
Jason Thomson, Kjell Johnson, Robert Chapin, Donald Stedman, Steven Kumpf

Birth Defects Res B Dev Reprod Toxicol· April 2011

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The ensemble bridge algorithm: a new modeling tool for drug discovery problems.
Mark Culp, Kjell Johnson, George Michailidis

J Chem Inf Model· February 2010

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The development and validation of a computational model to predict rat liver microsomal clearance.
Cheng Chang, David B Duignan, Kjell D Johnson, Pil H Lee, George S Cowan

J Pharm Sci· August 2009

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Beyond pass/fail: a procedure for evaluating the effect of carryover in bioanalytical LC/MS/MS methods.
Andrea Clouser-Roche, Kjell Johnson, Douglas Fast, Daniel Tang

J Pharm Biomed Anal· May 2008

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Identifying promising compounds in drug discovery: genetic algorithms and some new statistical techniques.
Abhyuday Mandal, Kjell Johnson, C F Jeff Wu, Dirk Bornemeier

J Chem Inf Model· September 2007

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Porcine brain microvessel endothelial cells as an in vitro model to predict in vivo blood-brain barrier permeability.
Yan Zhang, Cheryl S W Li, Yuyang Ye, Kjell Johnson, Julie Poe, Shannon Johnson

Drug Metab Dispos· November 2006

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An efficient approach for the rapid assessment of oral rat exposures for new chemical entities in drug discovery.
Hyo-Kyung Han, Nalini Sadagopan, Gregory A Reichard, Udeni Yapa, Tong Zhu, Kjell Johnson

J Pharm Sci· August 2006

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