Publications by authors named "Klaus Scheffzek"

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Mechanistic Insights into Substrate Recognition of Human Nucleoside Diphosphate Kinase C Based on Nucleotide-Induced Structural Changes.
Rezan Amjadi, Sebastiaan Werten, Santosh Kumar Lomada, Clara Baldin, Klaus Scheffzek

Int J Mol Sci· September 2024

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Structural basis of activation of the tumor suppressor protein neurofibromin.
Malik Chaker-Margot, Sebastiaan Werten, Theresia Dunzendorfer-Matt, Stefan Lechner, Angela Ruepp, Klaus Scheffzek

Mol Cell· April 2022

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Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR.
Wupeng Yan, Evan Markegard, Srisathiyanarayanan Dharmaiah, Anatoly Urisman, Matthew Drew, Klaus Scheffzek

Cell Rep· July 2020

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A 6&1-FEH Encodes an Enzyme for Fructan Degradation and Interact with Invertase Inhibitor Protein in Maize ( L.).
Hongbo Zhao, Steffen Greiner, Klaus Scheffzek, Thomas Rausch, Guoping Wang

Int J Mol Sci· August 2019

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Plant glutathione biosynthesis revisited: redox-mediated activation of glutamylcysteine ligase does not require homo-dimerization.
Yingxue Yang, Esther D Lenherr, Roland Gromes, Shanshan Wang, Markus Wirtz, Klaus Scheffzek

Biochem J· April 2019

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Ras-Specific GTPase-Activating Proteins-Structures, Mechanisms, and Interactions.
Klaus Scheffzek, Giridhar Shivalingaiah

Cold Spring Harb Perspect Med· March 2019

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Structural basis for the bi-functionality of human oxaloacetate decarboxylase FAHD1.
Alexander K H Weiss, Andreas Naschberger, Johannes R Loeffler, Hubert Gstach, Matthew W Bowler, Klaus Scheffzek

Biochem J· November 2018

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MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms.
Marek Kozlowski, David Corujo, Michael Hothorn, Iva Guberovic, Imke K Mandemaker, Klaus Scheffzek

EMBO Rep· October 2018

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Expression, Purification, and Biochemical Characterization of Human Afamin.
Alessandra Altamirano, Andreas Naschberger, Barbara G Fürnrohr, Radka Saldova, Weston B Struwe, Klaus Scheffzek

J Proteome Res· March 2018

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LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.
Przemyslaw A Filipek, Mariana E G de Araujo, Georg F Vogel, Cedric H De Smet, Daniela Eberharter, Klaus Scheffzek

J Cell Biol· December 2017

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NMR resonance assignments of the EVH1 domain of neurofibromin's recruitment factor Spred1.
Sebastian Führer, Linda Ahammer, Angela Ausserbichler, Klaus Scheffzek, Theresia Dunzendorfer-Matt

Biomol NMR Assign· October 2017

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Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling.
Mariana E G de Araujo, Andreas Naschberger, Barbara G Fürnrohr, Taras Stasyk, Theresia Dunzendorfer-Matt, Klaus Scheffzek

Science· October 2017

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The N14 anti-afamin antibody Fab: a rare V1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling.
Andreas Naschberger, Barbara G Fürnrohr, Tihana Lenac Rovis, Suzana Malic, Klaus Scheffzek

Acta Crystallogr D Struct Biol· December 2016

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The neurofibromin recruitment factor Spred1 binds to the GAP related domain without affecting Ras inactivation.
Theresia Dunzendorfer-Matt, Ellen L Mercado, Karl Maly, Frank McCormick, Klaus Scheffzek

Proc Natl Acad Sci U S A· July 2016

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Cleaning protocols for crystallization robots: preventing protease contamination.
Andreas Naschberger, Barbara G Fürnrohr, Theresia Dunzendorfer-Matt, Christopher A Bonagura, David Wright, Klaus Scheffzek

Acta Crystallogr F Struct Biol Commun· January 2015

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Enhancing endosomal escape of transduced proteins by photochemical internalisation.
Kevin Mellert, Markus Lamla, Klaus Scheffzek, Rainer Wittig, Dieter Kaufmann

PLoS One· June 2013

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Functional MHC class II is upregulated in neurofibromin-deficient Schwann cells.
David E Reuss, Jana Mucha, Nikola Holtkamp, Ute Müller, Hans-Peter Berlien, Klaus Scheffzek

J Invest Dermatol· May 2013

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Mutations in SYNGAP1 cause intellectual disability, autism, and a specific form of epilepsy by inducing haploinsufficiency.
Martin H Berryer, Fadi F Hamdan, Laura L Klitten, Rikke S Møller, Lionel Carmant, Klaus Scheffzek

Hum Mutat· February 2013

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Pleckstrin homology (PH) like domains - versatile modules in protein-protein interaction platforms.
Klaus Scheffzek, Stefan Welti

FEBS Lett· August 2012

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Allosterically gated enzyme dynamics in the cysteine synthase complex regulate cysteine biosynthesis in Arabidopsis thaliana.
Anna Feldman-Salit, Markus Wirtz, Esther D Lenherr, Christian Throm, Michael Hothorn, Klaus Scheffzek

Structure· February 2012

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Inhibition and termination of physiological responses by GTPase activating proteins.
Erzsébet Ligeti, Stefan Welti, Klaus Scheffzek

Physiol Rev· January 2012

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Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin.
Stefan Welti, Sonja Kühn, Igor D'Angelo, Britta Brügger, Dieter Kaufmann, Klaus Scheffzek

Hum Mutat· February 2011

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Structure and function of the hetero-oligomeric cysteine synthase complex in plants.
Markus Wirtz, Hannah Birke, Corinna Heeg, Christopher Müller, Fabian Hosp, Klaus Scheffzek

J Biol Chem· October 2010

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Structural insights into the pH-controlled targeting of plant cell-wall invertase by a specific inhibitor protein.
Michael Hothorn, Wim Van den Ende, Willem Lammens, Vladimir Rybin, Klaus Scheffzek

Proc Natl Acad Sci U S A· October 2010

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Activity of the Enterococcus faecalis EIIA(gnt) PTS component and its strong interaction with EIIB(gnt).
Achim Brockmeier, Manuel Skopnik, Brigitte Koch, Christian Herrmann, Wolfgang Hengstenberg, Klaus Scheffzek

Biochem Biophys Res Commun· October 2009

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