Publications by authors named "Kong Nguyen"

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BIOPTIC B1 Ultra-High-Throughput Virtual Screening System Discovers LRRK2 Ligands in Vast Chemical Space.
Vlad Vinogradov, Kong T Nguyen, Simon Steshin, Ivan Izmailov, Andrey Doronichev

J Chem Inf Model· October 2025

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Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor.
Ahmed Mamai, Anh M Chau, Brian J Wilson, Iain D Watson, Babu B Joseph, Kong Nguyen

ACS Med Chem Lett· February 2023

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Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease.
Lucy Lin, Ealin N Patel, Alexander L Nielsen, Lewis D Turner, William H Tepp, Kong Nguyen

Int J Mol Sci· February 2023

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SPOP and OTUD7A Control EWS-FLI1 Protein Stability to Govern Ewing Sarcoma Growth.
Siyuan Su, Jianfeng Chen, Yao Jiang, Ying Wang, Tamara Vital, Kong T Nguyen

Adv Sci (Weinh)· July 2021

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Multimodal small-molecule screening for human prion protein binders.
Andrew G Reidenbach, Michael F Mesleh, Dominick Casalena, Sonia M Vallabh, Jayme L Dahlin, Kong T Nguyen

J Biol Chem· September 2020

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Miro1 Marks Parkinson's Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson's Models.
Chung-Han Hsieh, Li Li, Roeland Vanhauwaert, Kong T Nguyen, Mary D Davis

Cell Metab· December 2019

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Structural diversity of the epigenetics pocketome.
Alexandre Cabaye, Kong T Nguyen, Lihua Liu, Vineet Pande, Matthieu Schapira

Proteins· July 2015

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Bromo-deaza-SAH: a potent and selective DOT1L inhibitor.
Wenyu Yu, David Smil, Fengling Li, Wolfram Tempel, Oleg Fedorov, Kong T Nguyen

Bioorg Med Chem· April 2013

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Strategy to target the substrate binding site of SET domain protein methyltransferases.
Kong T Nguyen, Fengling Li, Gennadiy Poda, David Smil, Masoud Vedadi

J Chem Inf Model· March 2013

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Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction.
Yuri Bolshan, Matthäus Getlik, Ekaterina Kuznetsova, Gregory A Wasney, Taraneh Hajian, Kong T Nguyen

ACS Med Chem Lett· March 2013

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Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
Guillermo Senisterra, Hong Wu, Abdellah Allali-Hassani, Gregory A Wasney, Dalia Barsyte-Lovejoy, Kong T Nguyen

Biochem J· January 2013

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Normalizing molecular docking rankings using virtually generated decoys.
Izhar Wallach, Navdeep Jaitly, Kong Nguyen, Matthieu Schapira, Ryan Lilien

J Chem Inf Model· August 2011

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Structural chemistry of the histone methyltransferases cofactor binding site.
Valérie Campagna-Slater, Man Wai Mok, Kong T Nguyen, Miklos Feher, Rafael Najmanovich

J Chem Inf Model· March 2011

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Exploring α7-Nicotinic Receptor Ligand Diversity by Scaffold Enumeration from the Chemical Universe Database GDB.
Noemi Garcia-Delgado, Sonia Bertrand, Kong T Nguyen, Ruud van Deursen, Daniel Bertrand

ACS Med Chem Lett· November 2010

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Identification of selective norbornane-type aspartate analogue inhibitors of the glutamate transporter 1 (GLT-1) from the chemical universe generated database (GDB).
Erika Luethi, Kong T Nguyen, Marc Bürzle, Lorenz C Blum, Yoshiro Suzuki

J Med Chem· October 2010

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Classification of organic molecules by molecular quantum numbers.
Kong T Nguyen, Lorenz C Blum, Ruud van Deursen, Jean-Louis Reymond

ChemMedChem· November 2009

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3-(aminomethyl)piperazine-2,5-dione as a novel NMDA glycine site inhibitor from the chemical universe database GDB.
Kong Thong Nguyen, Erika Luethi, Salahuddin Syed, Stephan Urwyler, Sonia Bertrand

Bioorg Med Chem Lett· July 2009

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Discovery of NMDA glycine site inhibitors from the chemical universe database GDB.
Kong Thong Nguyen, Salahuddin Syed, Stephan Urwyler, Sonia Bertrand, Daniel Bertrand

ChemMedChem· October 2008

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