Publications by authors named "Kristen Chevalier"

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Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET.
Joost Neijssen, Rosa M F Cardoso, Kristen M Chevalier, Luus Wiegman, Thomas Valerius

J Biol Chem· August 2021

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Amivantamab (JNJ-61186372), an Fc Enhanced EGFR/cMet Bispecific Antibody, Induces Receptor Downmodulation and Antitumor Activity by Monocyte/Macrophage Trogocytosis.
Smruthi Vijayaraghavan, Lorraine Lipfert, Kristen Chevalier, Barbara S Bushey, Benjamin Henley

Mol Cancer Ther· October 2020

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The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors.
Bin Zhu, Peter J Connolly, Yue-Mei Zhang, Mark E McDonnell, Haiyan Bian, Kristen M Chevalier

Bioorg Med Chem Lett· July 2020

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The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL).
Bin Zhu, Peter J Connolly, Sui-Po Zhang, Kristen M Chevalier, Cynthia M Milligan

Bioorg Med Chem Lett· June 2020

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Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor.
Ryan M Wyatt, Ian Fraser, Natalie Welty, Brian Lord, Michelle Wennerholm, Kristen Chevalier

J Pharmacol Exp Ther· March 2020

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Erratum: Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity.
John D Douglass, Yin Xiu Zhou, Amy Wu, John A Zadroga, Angela M Gajda, Kristen M Chevalier

J Lipid Res· March 2019

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A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors.
Sheri L Moores, Mark L Chiu, Barbara S Bushey, Kristen Chevalier, Leopoldo Luistro

Cancer Res· July 2016

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Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity.
John D Douglass, Yin Xiu Zhou, Amy Wu, John A Zadroga, Angela M Gajda, Kristen M Chevalier

J Lipid Res· June 2015

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Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine.
Ellen E Codd, Judith Baker, Michael R Brandt, Stewart Bryant, Chaozhong Cai, Kristen M Chevalier

Toxicol Sci· October 2010

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Ex vivo delta opioid receptor autoradiography: CNS receptor occupancy of two novel compounds over their antihyperalgesic dose range.
Ellen E Codd, Jianya Ma, Sui-Po Zhang, Dennis J Stone, Raymond W Colburn, Kristen M Chevalier

Pharmacol Biochem Behav· August 2010

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Triazinediones as prokineticin 1 receptor antagonists. Part 1: SAR, synthesis and biological evaluation.
Janet L Ralbovsky, Joseph G Lisko, Jeffrey M Palmer, John Mabus, Kristen M Chevalier

Bioorg Med Chem Lett· May 2009

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