Publications by authors named "Kyle Fraser"

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LRRK2 as a Potential Disease-Modifying Target in Sporadic Parkinson's Disease.
Anthony E Lang, Robert A Hauser, Lorraine V Kalia, Bonnie Hersh, Zdenek Berger, Kyle Fraser

Mov Disord· December 2025

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Novel method for detection of UBE3A protein in CSF from individuals with Angelman syndrome.
Omar S Mabrouk, Nicole T Comfort Harris, Robert W Komorowski, Kyle Fraser, Elizabeth Berry-Kravis

Mol Genet Metab· July 2025

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Radiological markers of CSF α-synuclein aggregation in Parkinson's disease patients.
Amgad Droby, Avital Yoffe-Vasiliev, Daniel Atias, Kyle B Fraser, Omar S Mabrouk

NPJ Parkinsons Dis· January 2025

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Quantification of cinpanemab (BIIB054) binding to α-synuclein in cerebrospinal fluid of phase 1 single ascending dose samples.
YuTing Liu, Minhua Yang, Kyle Fraser, Danielle Graham, Paul H Weinreb

J Pharmacol Exp Ther· January 2025

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Cinpanemab in Early Parkinson Disease: Evaluation of Biomarker Results From the Phase 2 SPARK Clinical Trial.
R Matthew Hutchison, Kyle Fraser, Minhua Yang, Tara Fox, Elizabeth Hirschhorn

Neurology· March 2024

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Exploration of Bis-Cinnamido-Polyamines as Intrinsic Antimicrobial Agents and Antibiotic Enhancers.
Melissa M Cadelis, Jisoo Kim, Florent Rouvier, Evangelene S Gill, Kyle Fraser

Biomolecules· July 2023

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Investigation of Naphthyl-Polyamine Conjugates as Antimicrobials and Antibiotic Enhancers.
Melissa M Cadelis, Liam R Edmeades, Dan Chen, Evangelene S Gill, Kyle Fraser

Antibiotics (Basel)· June 2023

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LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease.
Danna Jennings, Sarah Huntwork-Rodriguez, Maurits F J M Vissers, Vinay M Daryani, Dolores Diaz, Kyle Fraser

Mov Disord· March 2023

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α,ω-Diacyl-Substituted Analogues of Natural and Unnatural Polyamines: Identification of Potent Bactericides That Selectively Target Bacterial Membranes.
Dan Chen, Melissa M Cadelis, Florent Rouvier, Thomas Troia, Liam R Edmeades, Kyle Fraser

Int J Mol Sci· March 2023

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Trial of Cinpanemab in Early Parkinson's Disease.
Anthony E Lang, Andrew D Siderowf, Eric A Macklin, Werner Poewe, David J Brooks, Kyle Fraser

N Engl J Med· August 2022

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Glucocerebrosidase Activity Is Not Associated with Parkinson's Disease Risk or Severity.
Nurit Omer, Nir Giladi, Tanya Gurevich, Anat Bar-Shira, Mali Gana-Weisz, Kyle B Fraser

Mov Disord· March 2022

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Glucocerebrosidase Activity is not Associated with Parkinson's Disease Risk or Severity.
Nurit Omer, Nir Giladi, Tanya Gurevich, Anat Bar-Shira, Mali Gana-Weisz, Kyle B Fraser

Mov Disord· January 2022

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Corrigendum to "α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration" [Neurobiol. Dis., Volume 105 (2017) Article 84, 98].
Hisham Abdelmotilib, Tyler Maltbie, Vedad Delic, Zhiyong Liu, Xianzhen Hu, Kyle B Fraser

Neurobiol Dis· November 2021

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Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity.
Aron Gyuris, Jose Navarrete-Perea, Ala Jo, Simona Cristea, Shuang Zhou, Kyle Fraser

Cell Rep· June 2019

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GNAQ and PMS1 Mutations Associated with Uveal Melanoma, Ocular Surface Melanosis, and Nevus of Ota.
Christopher B Toomey, Kyle Fraser, John A Thorson, Michael H Goldbaum, Jonathan H Lin

Ocul Oncol Pathol· June 2019

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Characterization of single microvesicles in plasma from glioblastoma patients.
Kyle Fraser, Ala Jo, Jimmy Giedt, Claudio Vinegoni, Katherine S Yang

Neuro Oncol· May 2019

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Sender Gender Influences Emoji Interpretation in Text Messages.
Sarah E Butterworth, Traci A Giuliano, Justin White, Lizette Cantu, Kyle C Fraser

Front Psychol· April 2019

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Multiplexed Profiling of Single Extracellular Vesicles.
Kyungheon Lee, Kyle Fraser, Bassel Ghaddar, Katy Yang, Eunha Kim

ACS Nano· January 2018

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Integrated Kidney Exosome Analysis for the Detection of Kidney Transplant Rejection.
Jongmin Park, Hsing-Ying Lin, Jean Pierre Assaker, Sangmoo Jeong, Chen-Han Huang, Kyle Fraser

ACS Nano· November 2017

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α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration.
Hisham Abdelmotilib, Tyler Maltbie, Vedad Delic, Zhiyong Liu, Xianzhen Hu, Kyle B Fraser

Neurobiol Dis· September 2017

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LRRK2 levels in immune cells are increased in Parkinson's disease.
D A Cook, G T Kannarkat, A F Cintron, Laura M Butkovich, Kyle B Fraser

NPJ Parkinsons Dis· March 2017

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Ser(P)-1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease.
Kyle B Fraser, Ashlee B Rawlins, Rachel G Clark, Roy N Alcalay, David G Standaert

Mov Disord· October 2016

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G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons.
Laura A Volpicelli-Daley, Hisham Abdelmotilib, Zhiyong Liu, Lindsay Stoyka, João Paulo Lima Daher, Kyle Fraser

J Neurosci· July 2016

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Toll-Like Receptor 4 Engagement Mediates Prolyl Endopeptidase Release from Airway Epithelia via Exosomes.
Tomasz Szul, Preston E Bratcher, Kyle B Fraser, Michele Kong, Rabindra Tirouvanziam

Am J Respir Cell Mol Biol· March 2016

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Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.
Kyle B Fraser, Mark S Moehle, Roy N Alcalay, Andrew B West,

Neurology· March 2016

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