Publications by authors named "Larry Bratton"

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Synthesis of novel 6-azacytidine prodrugs as potent influenza A inhibitors.
Omar Moukha-Chafiq, Larry D Bratton, Shuklendu D Karyakarte, Kathy Keith, Yohanka Martinez-Gzegozewska

Bioorg Med Chem Lett· February 2026

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Discovery of a novel non-toxic analog of clofarabine for the treatment of triple-negative breast cancer.
Omar Moukha-Chafiq, Rebecca Boohaker, Larry D Bratton, Marina Fosso Yatchang, Anish K Vadukoot

Bioorg Med Chem Lett· December 2025

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Targeting the HuR Oncogenic Role with a New Class of Cytoplasmic Dimerization Inhibitors.
Natalia Filippova, Xiuhua Yang, Subramaniam Ananthan, Jennifer Calano, Vibha Pathak, Larry Bratton

Cancer Res· April 2021

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Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring.
Mark L Boys, Feng Bian, James B Kramer, Christopher L Chio, Xiao-Dan Ren, Larry D Bratton

Bioorg Med Chem Lett· May 2012

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Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Ronald W Sarver, Elizabeth Bills, Gary Bolton, Larry D Bratton, Nicole L Caspers

J Med Chem· July 2008

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Discovery of pyrrole-based hepatoselective ligands as potent inhibitors of HMG-CoA reductase.
Larry D Bratton, Bruce Auerbach, Chulho Choi, Lisa Dillon, Jeffrey C Hanselman

Bioorg Med Chem· August 2007

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Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors.
Jeffrey A Pfefferkorn, Yuntao Song, Kuai-Lin Sun, Steven R Miller, Bharat K Trivedi, Larry D Bratton

Bioorg Med Chem Lett· August 2007

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Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) delta agonists.
Larry D Bratton, Gary F Filzen, Andrew Geyer, Jennifer K Hoffman, Gina Lu

Bioorg Med Chem Lett· July 2007

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Synthesis and SAR of selective benzothiophene, benzofuran, and indole-based peroxisome proliferator-activated receptor delta agonists.
Gary F Filzen, Larry Bratton, Xue-Min Cheng, Noe Erasga, Andrew Geyer

Bioorg Med Chem Lett· July 2007

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