Publications by authors named "Lars Neumann"

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Allosteric targeting of RIPK1: discovery of novel inhibitors parallel virtual screening and structure-guided optimization.
R S K Vijayan, Matthew M Hamilton, Dana E Pfaffinger, Fernando G Alvarez, Naphtali J Reyna, Lars Neumann

RSC Med Chem· September 2025

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Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening.
Tuomo Kalliokoski, Henna Kettunen, Esa Kumpulainen, Emilia Kettunen, Gabriel Thieulin-Pardo, Lars Neumann

Bioorg Med Chem Lett· October 2023

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Functional impact and molecular binding modes of drugs that target the PI3K isoform p110δ.
Floyd Hassenrück, Maria Farina-Morillas, Lars Neumann, Francesco Landini, Stuart James Blakemore

Commun Biol· June 2023

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Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors.
Qinglin Pu, Hongjun Zhang, Liangqin Guo, Mangeng Cheng, Amy C Doty, Lars Neumann

ACS Med Chem Lett· August 2020

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Radiographic images are inapplicable for a precise evaluation of the femoral tunnel position following MPFL reconstruction.
Vera Jaecker, Lars Neumann, Sven Shafizadeh, Paola Koenen, Ajay C Kanakamedala

Knee Surg Sports Traumatol Arthrosc· November 2019

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Peritoneal dialysis catheter leakage following intermittent vacuum therapy.
Esther Leenen, Lars Neumann, Ana Harth, Achim Jörres, Alexander Weidemann

Clin Kidney J· October 2018

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Sensitive Detection of the Natural Killer Cell-Mediated Cytotoxicity of Anti-CD20 Antibodies and Its Impairment by B-Cell Receptor Pathway Inhibitors.
Floyd Hassenrück, Eva Knödgen, Elisa Göckeritz, Safi Hasan Midda, Verena Vondey, Lars Neumann

Biomed Res Int· September 2018

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Establishing a chemical genetic link between Bruton tyrosine kinase activity in malignant B cells and cell functions involved in the micro-environmental dialogue.
Elisa Göckeritz, Verena Vondey, Anna Guastafierro, Maja Pizevska, Floyd Hassenrück, Lars Neumann

Br J Haematol· September 2017

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Cytotoxicity of the CD37 antibody BI 836826 against chronic lymphocytic leukaemia cells in combination with chemotherapeutic agents or PI3K inhibitors.
Günter Krause, Imaan Baki, Susan Kerwien, Eva Knödgen, Lars Neumann

Br J Haematol· June 2016

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Efficacy of phosphatidylinositol-3 kinase inhibitors with diverse isoform selectivity profiles for inhibiting the survival of chronic lymphocytic leukemia cells.
Elisa Göckeritz, Susan Kerwien, Michael Baumann, Marion Wigger, Verena Vondey, Lars Neumann

Int J Cancer· November 2015

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One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists.
Johannes Schiebel, Nedyalka Radeva, Helene Köster, Alexander Metz, Timo Krotzky, Lars Neumann

ChemMedChem· September 2015

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A resonant scanning dipole-antenna probe for enhanced nanoscale imaging.
Lars Neumann, Jorick van 't Oever, Niek F van Hulst

Nano Lett· November 2013

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Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability.
Benjamin E L Lauffer, Robert Mintzer, Rina Fong, Susmith Mukund, Christine Tam, Lars Neumann

J Biol Chem· September 2013

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Structure-kinetic relationship study of CDK8/CycC specific compounds.
Elisabeth V Schneider, Jark Böttcher, Robert Huber, Klaus Maskos, Lars Neumann

Proc Natl Acad Sci U S A· May 2013

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Ultrabright bowtie nanoaperture antenna probes studied by single molecule fluorescence.
Mathieu Mivelle, Thomas S van Zanten, Lars Neumann, Niek F van Hulst, Maria F Garcia-Parajo

Nano Lett· November 2012

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A small nonrule of 3 compatible fragment library provides high hit rate of endothiapepsin crystal structures with various fragment chemotypes.
Helene Köster, Tobias Craan, Sascha Brass, Christian Herhaus, Matthias Zentgraf, Lars Neumann

J Med Chem· November 2011

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HTS reporter displacement assay for fragment screening and fragment evolution toward leads with optimized binding kinetics, binding selectivity, and thermodynamic signature.
Lars Neumann, Konstanze von König, Dirk Ullmann

Methods Enzymol· June 2011

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Extraordinary optical transmission brightens near-field fiber probe.
Lars Neumann, Yuanjie Pang, Amel Houyou, Mathieu L Juan, Reuven Gordon

Nano Lett· February 2011

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The 'retro-design' concept for novel kinase inhibitors.
Gerhard Müller, Peter C Sennhenn, Timothy Woodcock, Lars Neumann

IDrugs· July 2010

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Fragment-based lead generation: identification of seed fragments by a highly efficient fragment screening technology.
Lars Neumann, Allegra Ritscher, Gerhard Müller, Doris Hafenbradl

J Comput Aided Mol Des· August 2009

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An RNA molecule that specifically inhibits G-protein-coupled receptor kinase 2 in vitro.
Günter Mayer, Bernhard Wulffen, Christian Huber, Jörg Brockmann, Birgit Flicke, Lars Neumann

RNA· March 2008

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Functional outcome of surgical treatment of symptomatic nonunion and malunion of midshaft clavicle fractures.
Nahum Rosenberg, Lars Neumann, Angus W Wallace

J Shoulder Elbow Surg· January 2008

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Chronic acromioclavicular separation: the medium term results of coracoclavicular ligament reconstruction using braided polyester prosthetic ligament.
In-Ho Jeon, Girish Dewnany, Richard Hartley, Lars Neumann, W Angus Wallace

Injury· November 2007

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Improvements in survival of the uncemented Nottingham Total Shoulder prosthesis: a prospective comparative study.
Nahum Rosenberg, Lars Neumann, Amit Modi, Istvan J Mersich, Angus W Wallace

BMC Musculoskelet Disord· August 2007

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One-stage arthroplasty of the ipsilateral shoulder and elbow.
Basil C Vrettos, Lars Neumann, Ann MacKie, Dorcas Damrel, W Angus Wallace

J Shoulder Elbow Surg· October 2005

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