Publications by authors named "Laura D Wood"

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TP53/KRAS variant allele frequency ratio predicts advanced disease in mucin-producing cystic neoplasms of the pancreas.
Ming-Tseh Lin, Elham Afghani, Marcia I Canto, Jing Zhu, Syed Z Ali, Laura D Wood

Am J Clin Pathol· December 2025

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Context-dependent inhibitory roles of RhoA in 3D invasive cell migration within the extracellular matrix.
Wakiko Iwata, Yoshihiro Adachi, Junior J West, Andrew J Ewald, Yi Zheng, Laura D Wood

Cell Rep· December 2025

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Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct patterns and potential markers of progression.
Yuefan Wang, Tung-Shing M Lih, Jae W Lee, Takao Ohtsuka, Yuto Hozaka, Laura D Wood

Cancer Cell· November 2025

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Integrative analysis of genomic and transcriptomic data informs precancer progression in the pancreas.
Kathleen Noller, Jiaying Lai, Daniel Lesperance, Ricky S Adkins, Ahmed Elhossiny, Laura D Wood

bioRxiv· November 2025

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Spatial profiling of human pancreatic ductal adenocarcinoma reveals molecular alterations associated with venous invasion.
Alexander T F Bell, Peter Chianchiano, Katsuya Hirose, Daniel Salas-Escabillas, Doreen M Zucha, Laura D Wood

Sci Transl Med· September 2025

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Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer: clinicopathological, genomic, and transcriptomic characterization.
Antonio Pea, Michele Bevere, Anastasios Gkountakos, Davide Pasini, Denise Fiorini, Laura D Wood

J Pathol· August 2025

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Spatial proteomics and transcriptomics reveal early immune cell organization in pancreatic intraepithelial neoplasia.
Melissa R Lyman, Jacob T Mitchell, Sidharth Raghavan, Luciane T Kagohara, Amanda L Huff, Laura D Wood

JCI Insight· August 2025

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Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories.
Jeanette A I Johnson, Daniel R Bergman, Heber L Rocha, David L Zhou, Eric Cramer, Laura D Wood

Cell· August 2025

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Multiregion Genomic Analysis of Human Pancreatic Mucinous Cystic Neoplasms.
Michael J Pflüger, Kohei Fujikura, Alicia M Braxton, Jae W Lee, Doreen M Zucha, Laura D Wood

Mod Pathol· July 2025

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Early neoplastic lesions of the pancreas: initiation, progression, and opportunities for precancer interception.
Brian A Pedro, Laura D Wood

J Clin Invest· July 2025

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Myc and Kras cooperate in adult acinar cells to drive phenotypic heterogeneity, metastasis, and therapeutic resistance in a novel pancreatic cancer mouse model.
Isabel A English, Patrick J Worth, Kevin Alexander MacPherson-Hawthorne, Macarena Vergara, Katherine Pelz, Laura D Wood

bioRxiv· July 2025

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Three-dimensional assessments are necessary to determine the true, spatially resolved composition of tissues.
André Forjaz, Eduarda Vaz, Valentina Matos Romero, Saurabh Joshi, Vasco Queiroga, Laura D Wood

Cell Rep Methods· June 2025

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PIVOT: an open-source tool for multi-omic spatial data registration.
André Forjaz, Valentina Matos Romero, Ian Reucroft, Margaret Eminizer, Donald Kramer, Laura D Wood

bioRxiv· June 2025

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Modeling cellular influence delineates functionally relevant cellular neighborhoods in primary and metastatic pancreatic ductal adenocarcinoma.
Yeonju Cho, Jae W Lee, Sarah M Shin, Alexei G Hernandez, Xuan Yuan, Laura D Wood

bioRxiv· June 2025

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Tumor immune microenvironment alterations associated with progression in human intraductal papillary mucinous neoplasms.
Kevin T Jamouss, Alexander Ioannis Damanakis, Abigail C Cornwell, Martine Jongepier, Maria A Trujillo, Laura D Wood

J Pathol· May 2025

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P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids.
Bernat Navarro-Serer, Maria F Wissler, Brandi K Glover, Michael G Lerner, Harsh H Oza, Laura D Wood

Cancer Res Commun· May 2025

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Correction: Comprehensive DNA Methylation Analysis Indicates That Pancreatic Intraepithelial Neoplasia Lesions Are Acinar-Derived and Epigenetically Primed for Carcinogenesis.
Emily K W Lo, Brian M Mears, H Carlo Maurer, Adrian Idrizi, Kasper D Hansen, Laura D Wood

Cancer Res· April 2025

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Ductal Cancerization at the Pancreatic Neck Margin: Prevalence and Oncologic Relevance.
Michael J Pflüger, Doreen M Zucha, Benedict Kinny-Köster, Brian A Pedro, Jiayun Lu, Laura D Wood

Ann Surg· March 2025

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The Evolutionary Forest of Pancreatic Cancer.
Katelyn M Mullen, Jungeui Hong, Marc A Attiyeh, Akimasa Hayashi, Hitomi Sakamoto, Laura D Wood

Cancer Discov· February 2025

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SVCFit: Inferring structural variant cellular fraction in tumors.
Yunzhou Liu, Jiaying Lai, Laura D Wood, Rachel Karchin

bioRxiv· February 2025

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From precursor to cancer: decoding the intrinsic and extrinsic pathways of pancreatic intraepithelial neoplasia progression.
Sarah Graham, Mariia Dmitrieva, Debora Barbosa Vendramini-Costa, Ralph Francescone, Maria A Trujillo, Laura D Wood

Carcinogenesis· November 2024

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PanIN and CAF transitions in pancreatic carcinogenesis revealed with spatial data integration.
Alexander T F Bell, Jacob T Mitchell, Ashley L Kiemen, Melissa Lyman, Kohei Fujikura, Laura D Wood

Cell Syst· August 2024

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3D histology reveals that immune response to pancreatic precancers is heterogeneous and depends on global pancreas structure.
Ashley L Kiemen, Cristina Almagro-Pérez, Valentina Matos, Andre Forjaz, Alicia M Braxton, Laura D Wood

bioRxiv· August 2024

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Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct expression patterns and potential markers of progression.
Yuefan Wang, T Mamie Lih, Jae W Lee, Takao Ohtsuka, Yuto Hozaka, Laura D Wood

bioRxiv· July 2024

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Power-law growth models explain incidences and sizes of pancreatic cancer precursor lesions and confirm spatial genomic findings.
Ashley L Kiemen, Pei-Hsun Wu, Alicia M Braxton, Toby C Cornish, Ralph H Hruban, Laura D Wood

Sci Adv· July 2024

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