Publications by authors named "Laura Shireman"

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Using the Simcyp R Package for PBPK Simulation Workflows With the Simcyp Simulator.
Anthonia M Onasanwo, Naresh Mittapelly, Laura Shireman, Barry Vinden, Kevin McNally

CPT Pharmacometrics Syst Pharmacol· May 2025

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Prediction of Busulfan Clearance by Predose Plasma Metabolomic Profiling.
Jeannine S McCune, Sandi L Navarro, K Scott Baker, Linda J Risler, Brian R Phillips, Laura Shireman

Clin Pharmacol Ther· February 2023

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Reversibility and Low Commitment to Forward Catalysis in the Conjugation of Lipid Alkenals by Glutathione Transferase A4-4.
Michele Scian, Lorela Paço, Taylor A Murphree, Laura M Shireman, William M Atkins

Biomolecules· February 2023

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Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction.
Dennis D Wang, Sophia E Airhart, Bo Zhou, Laura M Shireman, Siyi Jiang

JACC Basic Transl Sci· December 2022

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Model-Based Analysis of the Influence of Alcohol Use and Age on Pharmacokinetics-Pharmacodynamics of Oral Oxycodone in Middle-Age and Older Community-Dwelling Adults.
Bojan B Lalovic, Laura Shireman, Danny D Shen, Monique M Cherrier

J Clin Pharmacol· September 2022

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Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 1: Model for the Free-Drug Mixture.
Simone Perazzolo, Laura M Shireman, Danny D Shen, Rodney J Y Ho

J Pharm Sci· February 2022

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Elevated customary alcohol consumption attenuates opioid effects.
Monique M Cherrier, Danny D Shen, Laura Shireman, Andrew J Saxon, Tracy Simpson

Pharmacol Biochem Behav· December 2021

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Nicotine metabolism and its association with CYP2A6 genotype among Indigenous people in Alaska who smoke.
Krista R Schaefer, Jaedon P Avey, Michael R Todd, Julie A Beans, Denise A Dillard, Laura M Shireman

Clin Transl Sci· November 2021

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Development and validation of a LC-MS/MS method for in vivo quantification of meta-iodobenzylguanidine (mIBG).
Antonio J López Quiñones, Laura M Shireman, Joanne Wang

J Chromatogr B Analyt Technol Biomed Life Sci· September 2021

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Assessing Transporter-Mediated Natural Product-Drug Interactions Via In vitro-In Vivo Extrapolation: Clinical Evaluation With a Probe Cocktail.
James T Nguyen, Dan-Dan Tian, Rakshit S Tanna, Deena L Hadi, Sumit Bansal, Laura M Shireman

Clin Pharmacol Ther· May 2021

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Prediction of Kidney Drug Clearance: A Comparison of Tubular Secretory Clearance and Glomerular Filtration Rate.
Yan Chen, Leila R Zelnick, Andrew N Hoofnagle, Catherine K Yeung, Laura M Shireman

J Am Soc Nephrol· February 2021

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Relationship of Phosphatidylethanol Biomarker to Self-Reported Alcohol Drinking Patterns in Older and Middle-Age Adults.
Monique M Cherrier, Laura M Shireman, Katie Wicklander, Winnie Yeung, Preetma Kooner

Alcohol Clin Exp Res· December 2020

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Corrigendum to: The Use of Metabolomics to Identify Biological Signatures of Manganese Exposure.
Marissa G Baker, Christopher D Simpson, Yvonne S Lin, Laura M Shireman, Noah Seixas

Ann Work Expo Health· November 2020

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LETTER TO THE EDITOR.
Monique Cherrier, Gregory Terman, Danny Shen, Laura Shireman, Andrew Saxon

J Am Osteopath Assoc· July 2020

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Pharmacodynamics of Glyburide, Metformin, and Glyburide/Metformin Combination Therapy in the Treatment of Gestational Diabetes Mellitus.
Diana L Shuster, Laura M Shireman, Xiaosu Ma, Danny D Shen, Shannon K Flood Nichols

Clin Pharmacol Ther· June 2020

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Integration of Computational and Experimental Approaches to Elucidate Mechanisms of First-Pass Lymphatic Drug Sequestration and Long-Acting Pharmacokinetics of the Injectable Triple-HIV Drug Combination TLC-ART 101.
Simone Perazzolo, Laura M Shireman, Lisa A McConnachie, Josefin Koehn, Loren Kinman

J Pharm Sci· May 2020

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Pharmacodynamics of Metformin in Pregnant Women With Gestational Diabetes Mellitus and Nonpregnant Women With Type 2 Diabetes Mellitus.
Diana L Shuster, Laura M Shireman, Xiaosu Ma, Danny D Shen, Shannon K Flood Nichols

J Clin Pharmacol· April 2020

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The reproducibility of urinary ions in manganese exposed workers.
Marissa G Baker, Yvonne S Lin, Christopher D Simpson, Laura M Shireman, Susan Searles Nielsen

J Trace Elem Med Biol· January 2019

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Three HIV Drugs, Atazanavir, Ritonavir, and Tenofovir, Coformulated in Drug-Combination Nanoparticles Exhibit Long-Acting and Lymphocyte-Targeting Properties in Nonhuman Primates.
Simone Perazzolo, Laura M Shireman, Josefin Koehn, Lisa A McConnachie, John C Kraft

J Pharm Sci· December 2018

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Disposition of Methamphetamine and Major Metabolites in Mice: Role of Organic Cation Transporter 3 in Tissue-Selective Accumulation of -Hydroxymethamphetamine.
David J Wagner, Laura M Shireman, Sojung Ahn, Danny D Shen, Joanne Wang

Drug Metab Dispos· September 2018

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An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers.
Sophia E Airhart, Laura M Shireman, Linda J Risler, Gail D Anderson, G A Nagana Gowda

PLoS One· January 2018

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P-gp/ABCB1 exerts differential impacts on brain and fetal exposure to norbuprenorphine.
Michael Z Liao, Chunying Gao, Laura M Shireman, Brian Phillips, Linda J Risler

Pharmacol Res· May 2017

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The Use of Metabolomics to Identify Biological Signatures of Manganese Exposure.
Marissa G Baker, Christopher D Simpson, Yvonne S Lin, Laura M Shireman, Noah Seixas

Ann Work Expo Health· May 2017

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Pharmacodynamics of Ceftaroline plus Ampicillin against Enterococcus faecalis in an Pharmacokinetic/Pharmacodynamic Model of Simulated Endocardial Vegetations.
Brian J Werth, Laura M Shireman

Antimicrob Agents Chemother· April 2017

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Prediction of Intravenous Busulfan Clearance by Endogenous Plasma Biomarkers Using Global Pharmacometabolomics.
Yvonne S Lin, Savannah J Kerr, Timothy Randolph, Laura M Shireman, Tauri Senn

Metabolomics· October 2016

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