Publications by authors named "Leah Prentice"

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The practice of genomic medicine: A delineation of the process and its governing principles.
Julia Handra, Adrienne Elbert, Nour Gazzaz, Ashley Moller-Hansen, Stephanie Hyunh, Leah M Prentice

Front Med (Lausanne)· January 2023

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The Clinical Variant Analysis Tool: Analyzing the evidence supporting reported genomic variation in clinical practice.
Hui-Lin Chin, Nour Gazzaz, Stephanie Huynh, Iulia Handra, Lynn Warnock, Leah M Prentice

Genet Med· July 2022

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Optimization of magnetic bead-based nucleic acid extraction for SARS-CoV-2 testing using readily available reagents.
Simon Haile, Aidan M Nikiforuk, Pawan K Pandoh, David D W Twa, Duane E Smailus, Leah M Prentice

J Virol Methods· January 2022

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Molecular characterization of invasive and in situ squamous neoplasia of the vulva and implications for morphologic diagnosis and outcome.
Basile Tessier-Cloutier, Jennifer Pors, Emily Thompson, Julie Ho, Leah Prentice

Mod Pathol· February 2021

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Major p53 immunohistochemical patterns in in situ and invasive squamous cell carcinomas of the vulva and correlation with TP53 mutation status.
Basile Tessier-Cloutier, Kim E Kortekaas, Emily Thompson, Jennifer Pors, Julia Chen, Leah M Prentice

Mod Pathol· August 2020

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c-KIT Analysis and Targeted Molecular Sequencing of Mesonephric Carcinomas of the Female Genital Tract.
Jennifer Pors, Julie Ho, Leah Prentice, Emily Thompson, Dawn Cochrane

Am J Surg Pathol· April 2020

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Selumetinib in patients receiving standard pemetrexed and platinum-based chemotherapy for advanced or metastatic KRAS wildtype or unknown non-squamous non-small cell lung cancer: A randomized, multicenter, phase II study. Canadian Cancer Trials Group (CCTG) IND.219.
Barbara Melosky, Penelope Bradbury, Dongsheng Tu, Marie Florescu, Anthony Reiman, Leah M Prentice

Lung Cancer· July 2019

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Leah M Prentice, Ruth R Miller, Jeff Knaggs, Alborz Mazloomian, Rosalia Aguirre Hernandez

PLoS One· August 2018

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Ciliated muconodular papillary tumors of the lung with KRAS/BRAF/AKT1 mutation.
Emiko Udo, Bungo Furusato, Kazuko Sakai, Leah M Prentice, Tomonori Tanaka

Diagn Pathol· August 2017

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Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes.
Yi Kan Wang, Ali Bashashati, Michael S Anglesio, Dawn R Cochrane, Diljot S Grewal, Leah M Prentice

Nat Genet· June 2017

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Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer.
Andrew McPherson, Andrew Roth, Emma Laks, Tehmina Masud, Ali Bashashati, Leah M Prentice

Nat Genet· July 2016

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Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden.
Michael S Anglesio, Ali Bashashati, Yi Kan Wang, Janine Senz, Gavin Ha, Leah M Prentice

J Pathol· June 2015

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A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation.
Angela Burleigh, Steven McKinney, Jazmine Brimhall, Damian Yap, Peter Eirew, Leah Prentice

Breast Cancer Res· January 2015

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TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data.
Gavin Ha, Andrew Roth, Jaswinder Khattra, Julie Ho, Damian Yap, Leah M Prentice

Genome Res· November 2014

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Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4.
Pilar Ramos, Anthony N Karnezis, David W Craig, Aleksandar Sekulic, Megan L Russell, Leah M Prentice

Nat Genet· May 2014

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Type-specific cell line models for type-specific ovarian cancer research.
Michael S Anglesio, Kimberly C Wiegand, Nataliya Melnyk, Christine Chow, Clara Salamanca, Leah M Prentice

PLoS One· April 2014

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Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles.
Melissa K McConechy, Jiarui Ding, Janine Senz, Winnie Yang, Nataliya Melnyk, Leah M Prentice

Mod Pathol· January 2014

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Biomarker-based ovarian carcinoma typing: a histologic investigation in the ovarian tumor tissue analysis consortium.
Martin Köbel, Steve E Kalloger, Sandra Lee, Máire A Duggan, Linda E Kelemen, Leah Prentice

Cancer Epidemiol Biomarkers Prev· October 2013

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Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling.
Ali Bashashati, Gavin Ha, Alicia Tone, Jiarui Ding, Leah M Prentice

J Pathol· September 2013

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Correction: Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research.
Michael S Anglesio, Kimberly C Wiegand, Nataliya Melnyk, Christine Chow, Clara Salamanca, Leah M Prentice

PLoS One· September 2013

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Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study.
Weiva Sieh, Martin Köbel, Teri A Longacre, David D Bowtell, Anna deFazio, Leah M Prentice

Lancet Oncol· August 2013

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Mutation discovery in regions of segmental cancer genome amplifications with CoNAn-SNV: a mixture model for next generation sequencing of tumors.
Anamaria Crisan, Rodrigo Goya, Gavin Ha, Jiarui Ding, Leah M Prentice

PLoS One· May 2013

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Use of mutation profiles to refine the classification of endometrial carcinomas.
Melissa K McConechy, Jiarui Ding, Maggie Cu Cheang, Kimberly Wiegand, Janine Senz, Leah Prentice

J Pathol· September 2012

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BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma.
Jessica N McAlpine, Henry Porter, Martin Köbel, Brad H Nelson, Leah M Prentice

Mod Pathol· May 2012

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The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
Sohrab P Shah, Andrew Roth, Rodrigo Goya, Arusha Oloumi, Gavin Ha, Leah M Prentice

Nature· April 2012

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