Publications by authors named "Leighton Core"

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Centromeric transposable elements and epigenetic status drive karyotypic variation in the eastern hoolock gibbon.
Gabrielle A Hartley, Mariam Okhovat, Savannah J Hoyt, Emily Fuller, Nicole Pauloski, Leighton Core

Cell Genom· April 2025

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Centromeric transposable elements and epigenetic status drive karyotypic variation in the eastern hoolock gibbon.
Gabrielle A Hartley, Mariam Okhovat, Savannah J Hoyt, Emily Fuller, Nicole Pauloski, Leighton Core

bioRxiv· August 2024

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From telomere to telomere: The transcriptional and epigenetic state of human repeat elements.
Savannah J Hoyt, Jessica M Storer, Gabrielle A Hartley, Patrick G S Grady, Ariel Gershman, Leighton J Core

Science· April 2022

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H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization.
Bobbie Pelham-Webb, Alexander Polyzos, Luke Wojenski, Andreas Kloetgen, Jiexi Li, Leighton Core

Mol Cell· April 2021

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An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion.
Kizhakke Mattada Sathyan, Brian D McKenna, Warren D Anderson, Fabiana M Duarte, Leighton Core

Genes Dev· October 2019

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Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation.
Leighton Core, Karen Adelman

Genes Dev· August 2019

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An AR-ERG transcriptional signature defined by long-range chromatin interactomes in prostate cancer cells.
Zhizhuo Zhang, Kern Rei Chng, Shreyas Lingadahalli, Zikai Chen, Mei Hui Liu, Leighton J Core

Genome Res· February 2019

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A bipartite boundary element restricts imprinting to mature neurons.
Jack S Hsiao, Noelle D Germain, Andrea Wilderman, Christopher Stoddard, Luke A Wojenski, Leighton Core

Proc Natl Acad Sci U S A· February 2019

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The RNA exosome contributes to gene expression regulation during stem cell differentiation.
Marta Lloret-Llinares, Evdoxia Karadoulama, Yun Chen, Luke A Wojenski, Geno J Villafano, Leighton Core

Nucleic Acids Res· November 2018

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Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme.
Tinyi Chu, Edward J Rice, Gregory T Booth, H Hans Salamanca, Zhong Wang, Leighton J Core

Nat Genet· November 2018

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Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq).
Dig Bijay Mahat, Hojoong Kwak, Gregory T Booth, Iris H Jonkers, Charles G Danko, Leighton J Core

Nat Protoc· August 2016

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Transcription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation.
Fabiana M Duarte, Nicholas J Fuda, Dig B Mahat, Leighton J Core, Michael J Guertin

Genes Dev· August 2016

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Human Gene Promoters Are Intrinsically Bidirectional.
Robin Andersson, Yun Chen, Leighton Core, John T Lis, Albin Sandelin

Mol Cell· November 2015

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Identification of active transcriptional regulatory elements from GRO-seq data.
Charles G Danko, Stephanie L Hyland, Leighton J Core, Andre L Martins, Colin T Waters

Nat Methods· May 2015

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Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers.
Leighton J Core, André L Martins, Charles G Danko, Colin T Waters, Adam Siepel

Nat Genet· December 2014

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Nuclear stability and transcriptional directionality separate functionally distinct RNA species.
Robin Andersson, Peter Refsing Andersen, Eivind Valen, Leighton J Core, Jette Bornholdt

Nat Commun· November 2014

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RNA-DNA differences are generated in human cells within seconds after RNA exits polymerase II.
Isabel X Wang, Leighton J Core, Hojoong Kwak, Lauren Brady, Alan Bruzel

Cell Rep· March 2014

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Pol II docking and pausing at growth and stress genes in C. elegans.
Colin S Maxwell, William S Kruesi, Leighton J Core, Nicole Kurhanewicz, Colin T Waters

Cell Rep· February 2014

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Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription.
Helena Kilpinen, Sebastian M Waszak, Andreas R Gschwind, Sunil K Raghav, Robert M Witwicki, Leighton J Core

Science· November 2013

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Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation.
William S Kruesi, Leighton J Core, Colin T Waters, John T Lis, Barbara J Meyer

Elife· June 2013

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Extensive polymerase pausing during Drosophila axis patterning enables high-level and pliable transcription.
Abbie Saunders, Leighton J Core, Catherine Sutcliffe, John T Lis, Hilary L Ashe

Genes Dev· May 2013

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Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells.
Charles G Danko, Nasun Hah, Xin Luo, André L Martins, Leighton Core

Mol Cell· April 2013

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Precise maps of RNA polymerase reveal how promoters direct initiation and pausing.
Hojoong Kwak, Nicholas J Fuda, Leighton J Core, John T Lis

Science· February 2013

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Defining the status of RNA polymerase at promoters.
Leighton J Core, Joshua J Waterfall, Daniel A Gilchrist, David C Fargo, Hojoong Kwak

Cell Rep· October 2012

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Fcp1 dephosphorylation of the RNA polymerase II C-terminal domain is required for efficient transcription of heat shock genes.
Nicholas J Fuda, Martin S Buckley, Wenxiang Wei, Leighton J Core, Colin T Waters

Mol Cell Biol· September 2012

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