Publications by authors named "Lena Tagmose"

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Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators.
Mathieu Botte, Sophie Huber, Denis Bucher, Julie K Klint, David Rodríguez, Lena Tagmose

PNAS Nexus· July 2022

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IMI European Lead Factory - democratizing access to high-throughput screening.
Philip S Jones, Sylviane Boucharens, Stuart P McElroy, Angus Morrison, Saman Honarnejad, Lena Tagmose

Nat Rev Drug Discov· April 2022

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Development of a Surface Plasmon Resonance Assay for the Characterization of Small-Molecule Binding Kinetics and Mechanism of Binding to Kynurenine 3-Monooxygenase.
Suresh B Poda, Masakazu Kobayashi, Ruta Nachane, Veena Menon, Adarsh S Gandhi, Lena Tagmose

Assay Drug Dev Technol· October 2015

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Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex.
Jacob Lauwring Andersen, Tenna Juul Schrøder, Søren Christensen, Dorthe Strandbygård, Lone Tjener Pallesen, Lena Tagmose

Acta Crystallogr D Biol Crystallogr· February 2014

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The identification of AF38469: an orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin.
Tenna Juul Schrøder, Søren Christensen, Samsa Lindberg, Morten Langgård, Laurent David, Lena Tagmose

Bioorg Med Chem Lett· January 2014

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Homology modeling of the serotonin transporter: insights into the primary escitalopram-binding site.
Anne Marie Jørgensen, Lena Tagmose, Anne Marie M Jørgensen, Sid Topiol, Michael Sabio

ChemMedChem· June 2007

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Molecular dynamics simulations of Na+/Cl(-)-dependent neurotransmitter transporters in a membrane-aqueous system.
Anne Marie Jørgensen, Lena Tagmose, Anne Marie M Jørgensen, Klaus P Bøgesø, Günther H Peters

ChemMedChem· June 2007

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Design and synthesis of a new series of 4-alkylated 3-isoxazolol GABA A antagonists.
Bente Frølund, Lena Tagmose, Anne T Jørgensen, Uffe Kristiansen, Tine B Stensbøl

Eur J Med Chem· April 2003

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Novel class of potent 4-arylalkyl substituted 3-isoxazolol GABA(A) antagonists: synthesis, pharmacology, and molecular modeling.
Bente Frølund, Anne T Jørgensen, Lena Tagmose, Tine B Stensbøl, Henrik T Vestergaard

J Med Chem· June 2002

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