Publications by authors named "Michael Sabio"

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Design and biological characterization of a series of dual mechanism ERK1/2 inhibitors with a Triazolopyridinone core.
Sajedeh Lotfaliansaremi, Stephen Cornwell, Candice Casillas, Michael Sabio, Peter Tolias

Chem Biol Drug Des· April 2023

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Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain.
Abhishek Sharma, Weiyi Toy, Valeria Sanabria Guillen, Naina Sharma, Jian Min, Michael Sabio

ACS Chem Biol· December 2018

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7TM X-ray structures for class C GPCRs as new drug-discovery tools. 1. mGluR5.
Sid Topiol, Michael Sabio

Bioorg Med Chem Lett· January 2016

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The role of experimental and computational structural approaches in 7TM drug discovery.
Sid Topiol, Michael Sabio

Expert Opin Drug Discov· October 2015

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cis-1-Oxo-heterocyclyl-4-amido cyclohexane derivatives as NPY5 receptor antagonists.
James Ford Burns, Bin Chen, Chien-An Chen, Dario Doller, Eman Edelmenky, Michael Sabio

Bioorg Med Chem Lett· March 2014

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4-(1-Phenyl-1H-pyrazol-4-yl)quinolines as novel, selective and brain penetrant metabotropic glutamate receptor 4 positive allosteric modulators.
Hermogenes N Jimenez, Kevin G Liu, Sang-Phyo Hong, Michael S Reitman, Michelle A Uberti, Michael Sabio

Bioorg Med Chem Lett· May 2012

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Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators.
Sang-Phyo Hong, Kevin G Liu, Gil Ma, Michael Sabio, Michelle A Uberti

J Med Chem· July 2011

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Exploration of structure-based drug design opportunities for mGluRs.
Sid Topiol, Michael Sabio, Michelle Uberti

Neuropharmacology· January 2011

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X-ray structure breakthroughs in the GPCR transmembrane region.
Sid Topiol, Michael Sabio

Biochem Pharmacol· July 2009

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Development of an aequorin luminescence calcium assay for high-throughput screening using a plate reader, the LumiLux.
Veena Menon, Arun Ranganathn, Vincent H Jorgensen, Michael Sabio, Claus T Christoffersen

Assay Drug Dev Technol· December 2008

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Use of the X-ray structure of the beta2-adrenergic receptor for drug discovery. Part 2: Identification of active compounds.
Michael Sabio, Kenneth Jones, Sid Topiol

Bioorg Med Chem Lett· October 2008

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Use of the X-ray structure of the Beta2-adrenergic receptor for drug discovery.
Sid Topiol, Michael Sabio

Bioorg Med Chem Lett· March 2008

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Homology modeling of the serotonin transporter: insights into the primary escitalopram-binding site.
Anne Marie Jørgensen, Lena Tagmose, Anne Marie M Jørgensen, Sid Topiol, Michael Sabio

ChemMedChem· June 2007

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1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1.
Sompong Wattanasin, Joerg Kallen, Stewart Myers, Qin Guo, Michael Sabio

Bioorg Med Chem Lett· February 2005

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Depletion of methionine aminopeptidase 2 does not alter cell response to fumagillin or bengamides.
Sunkyu Kim, Kenneth LaMontagne, Michael Sabio, Sushil Sharma, Richard W Versace

Cancer Res· May 2004

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1,4-Diazepane-2-ones as novel inhibitors of LFA-1.
Sompong Wattanasin, Rainer Albert, Claus Ehrhardt, Didier Roche, Michael Sabio

Bioorg Med Chem Lett· February 2003

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