Publications by authors named "Leo Barnes"

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Golcadomide: An Oral CELMoD Agent Targeting IKZF1/3 For Diffuse Large B-Cell Lymphoma.
Zhongying Mo, Lynda Groocock, Scott Wood, Diana Jankeel, Derek Mendy, Leo Barnes

Blood Cancer Discov· November 2025

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Synthetic Lethal Strategy Identifies a Potent and Selective TTK and CLK1/2 Inhibitor for Treatment of Triple-Negative Breast Cancer with a Compromised G-S Checkpoint.
Dan Zhu, Shuichan Xu, Gordafaried Deyanat-Yazdi, Sophie X Peng, Leo A Barnes

Mol Cancer Ther· August 2018

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The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen.
Jennifer R Riggs, Mark Nagy, Jan Elsner, Paul Erdman, Dan Cashion, Leo Barnes

J Med Chem· November 2017

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CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL.
Patrick R Hagner, Hon-Wah Man, Celia Fontanillo, Maria Wang, Suzana Couto, Leo Barnes

Blood· August 2015

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A Src family kinase inhibitor improves survival in experimental acute liver failure associated with elevated cerebral and circulating vascular endothelial growth factor levels.
Richard J Aspinall, Sara M Weis, Leo Barnes, Kimberly Lutu-Fuga, David J Bylund

Liver Int· September 2011

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Targeted nanogels: a versatile platform for drug delivery to tumors.
Eric A Murphy, Bharat K Majeti, Rajesh Mukthavaram, Lisette M Acevedo, Leo A Barnes

Mol Cancer Ther· June 2011

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Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.
Barbara Garmy-Susini, Christie J Avraamides, Michael C Schmid, Philippe Foubert, Lesley G Ellies, Leo Barnes

Cancer Res· April 2010

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RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia.
David J Shields, Sherry Niessen, Eric A Murphy, Ainhoa Mielgo, Jay S Desgrosellier, Leo A Barnes

Proc Natl Acad Sci U S A· February 2010

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An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression.
Jay S Desgrosellier, Leo A Barnes, David J Shields, Miller Huang, Steven K Lau

Nat Med· October 2009

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Extended-working-distance multiphoton micromanipulation microscope for deep-penetration imaging in live mice and tissue.
Milan Makale, Michele McElroy, Peter O'Brien, Robert M Hoffman, Sharon Guo, Leo Barnes

J Biomed Opt· July 2009

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Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis.
Jill M Ricono, Miller Huang, Leo A Barnes, Steven K Lau, Sara M Weis

Cancer Res· February 2009

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Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis.
Eric A Murphy, Bharat K Majeti, Leo A Barnes, Milan Makale, Sara M Weis

Proc Natl Acad Sci U S A· July 2008

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Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.
Sara M Weis, Ssang-Taek Lim, Kimberly M Lutu-Fuga, Leo A Barnes, Xiao Lei Chen

J Cell Biol· April 2008

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Cooperation between VEGF and beta3 integrin during cardiac vascular development.
Sara M Weis, Jeffrey N Lindquist, Leo A Barnes, Kimberly M Lutu-Fuga, Jianhua Cui

Blood· March 2007

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Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis.
Sara Weis, Jianhua Cui, Leo Barnes, David Cheresh

J Cell Biol· October 2004

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