Publications by authors named "Lewis Gowers"

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Optimization of a series of multi-isoform PI3 kinase inhibitors.
Benjamin Perry, Rebekah Beevers, Gavin Bennett, George Buckley, Tom Crabbe, Lewis Gowers

Bioorg Med Chem Lett· October 2008

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Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines.
Benjamin Perry, Rikki Alexander, Gavin Bennett, George Buckley, Tom Ceska, Lewis Gowers

Bioorg Med Chem Lett· August 2008

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IRAK-4 inhibitors. Part 1: a series of amides.
George M Buckley, Lewis Gowers, Alicia Perez Higueruelo, Kerry Jenkins, Stephen R Mack

Bioorg Med Chem Lett· June 2008

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IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo[1,2-a]pyridine binding.
George M Buckley, Thomas A Ceska, Joanne L Fraser, Lewis Gowers, Colin R Groom

Bioorg Med Chem Lett· June 2008

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Synthesis and structure-activity relationship of aminopyrimidine IKK2 inhibitors.
Alistair H Bingham, Richard J Davenport, Richard Fosbeary, Lewis Gowers, Roland L Knight

Bioorg Med Chem Lett· June 2008

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IRAK-4 inhibitors. Part III: a series of imidazo[1,2-a]pyridines.
George M Buckley, Richard Fosbeary, Joanne L Fraser, Lewis Gowers, Alicia P Higueruelo

Bioorg Med Chem Lett· June 2008

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Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors.
Mahbub Alam, Rebekah E Beevers, Tom Ceska, Richard J Davenport, Karen M Dickson, Lewis Gowers

Bioorg Med Chem Lett· June 2007

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A novel series of potent and selective IKK2 inhibitors.
Alistair H Bingham, Richard J Davenport, Lewis Gowers, Roland L Knight, Christopher Lowe

Bioorg Med Chem Lett· January 2004

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8-Methoxyquinoline-5-carboxamides as PDE4 inhibitors: a potential treatment for asthma.
George M Buckley, Nicola Cooper, Hazel J Dyke, Fiona P Galleway, Lewis Gowers

Bioorg Med Chem Lett· June 2002

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8-Methoxyquinolines as PDE4 inhibitors.
Motasim Billah, George M Buckley, Nicola Cooper, Hazel J Dyke, Robert Egan, Lewis Gowers

Bioorg Med Chem Lett· June 2002

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Synthesis and profile of SCH351591, a novel PDE4 inhibitor.
Motasim Billah, Nicola Cooper, Francis Cuss, Richard J Davenport, Hazel J Dyke, Lewis Gowers

Bioorg Med Chem Lett· June 2002

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7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 inhibitors: a potential treatment for asthma.
George M Buckley, Nicola Cooper, Richard J Davenport, Hazel J Dyke, Fiona P Galleway, Lewis Gowers

Bioorg Med Chem Lett· February 2002

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