Publications by authors named "Li-Tain Yeh"

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The Effects of Special Patient Population Plasma on Pharmacokinetic Quantifications Using LC-MS/MS.
Dongmei Zhou, Lifang Sun, Mai Nguyen, Li- Tain Yeh, David M Wilson

Drug Metab Lett· May 2020

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The Effect of Lesinurad in Combination With Allopurinol on Serum Uric Acid Levels in Patients With Gout.
Scott Baumgartner, Li-Tain Yeh, Zancong Shen, Bradley Kerr, Kimberly Manhard

J Clin Pharmacol· September 2018

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Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney.
Jeffrey N Miner, Philip K Tan, David Hyndman, Sha Liu, Cory Iverson, Li-Tain Yeh

Arthritis Res Ther· October 2016

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Erratum to: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney.
Jeffrey N Miner, Philip K Tan, David Hyndman, Sha Liu, Cory Iverson, Li-Tain Yeh

Arthritis Res Ther· October 2016

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In Vitro and In Vivo Interaction Studies Between Lesinurad, a Selective Urate Reabsorption Inhibitor, and Major Liver or Kidney Transporters.
Zancong Shen, Li-Tain Yeh, Kathleen Wallach, Nanqun Zhu, Brad Kerr

Clin Drug Investig· June 2016

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A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer.
Alex A Adjei, Donald A Richards, Anthony El-Khoueiry, Fadi Braiteh, Carlos H R Becerra, Li-Tain Yeh

Clin Cancer Res· May 2016

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Pharmacokinetics, pharmacodynamics, and safety of lesinurad, a selective uric acid reabsorption inhibitor, in healthy adult males.
Zancong Shen, Colin Rowlings, Brad Kerr, Vijay Hingorani, Kimberly Manhard, Li-Tain Yeh

Drug Des Devel Ther· April 2016

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Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia.
Roy Fleischmann, Bradley Kerr, Li-Tain Yeh, Matt Suster, Zancong Shen

Rheumatology (Oxford)· December 2014

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Multicenter phase I trial of the mitogen-activated protein kinase 1/2 inhibitor BAY 86-9766 in patients with advanced cancer.
Colin D Weekes, Daniel D Von Hoff, Alex A Adjei, Diane P Leffingwell, S Gail Eckhardt, Li-Tain Yeh

Clin Cancer Res· March 2013

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6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors.
Johnny Y Nagasawa, Jenny Song, Huanming Chen, Hong-Woo Kim, Julie Blazel, Li-Tain Yeh

Bioorg Med Chem Lett· January 2011

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Phase 2a randomized controlled trial of short-term activity, safety, and pharmacokinetics of a novel nonnucleoside reverse transcriptase inhibitor, RDEA806, in HIV-1-positive, antiretroviral-naive subjects.
Graeme Moyle, Marta Boffito, Albrecht Stoehr, Armin Rieger, Zancong Shen, Li-Tain Yeh

Antimicrob Agents Chemother· August 2010

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RDEA119/BAY 869766: a potent, selective, allosteric inhibitor of MEK1/2 for the treatment of cancer.
Cory Iverson, Gary Larson, Chon Lai, Li-Tain Yeh, Claudia Dadson

Cancer Res· September 2009

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Determination of N-acetyl retigabine in dog plasma by LC/MS/MS following off-line microElution 96-well solid phase extraction.
Wei Bu, Mai Nguyen, Christine Xu, Chin-Chung Lin, Li-Tain Yeh

J Chromatogr B Analyt Technol Biomed Life Sci· June 2007

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Cyclic monophosphate prodrugs of base-modified 2'-C-methyl ribonucleosides as potent inhibitors of hepatitis C virus RNA replication.
Esmir Gunic, Jean-Luc Girardet, Kanda Ramasamy, Vesna Stoisavljevic-Petkov, Suetying Chow, Li-Tain Yeh

Bioorg Med Chem Lett· May 2007

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P450 phenotyping of the metabolism of selegiline to desmethylselegiline and methamphetamine.
Salete A Benetton, Che Fang, Yan-ou Yang, Ramya Alok, Mey Year, Li-Tain Yeh

Drug Metab Pharmacokinet· April 2007

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LC-MS/MS method for simultaneous determination of viramidine and ribavirin levels in monkey red blood cells.
Li-Tain Yeh, Mai Nguyen, Sohelia Dadgostari, Wei Bu, Chin-Chung Lin

J Pharm Biomed Anal· February 2007

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A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors.
Zhijun Zhang, Wen Xu, Yung-Hyo Koh, Jae Hoon Shim, Jean-Luc Girardet, Li-Tain Yeh

Antimicrob Agents Chemother· February 2007

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Metabolic activation of pradefovir by CYP3A4 and its potential as an inhibitor or inducer.
Chin-chung Lin, Che Fang, Salete Benetton, Gui-fen Xu, Li-Tain Yeh

Antimicrob Agents Chemother· September 2006

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Absorption, metabolism, and excretion of [14C]viramidine in humans.
Chin-Chung Lin, Christine Xu, Nanqun Zhu, Li-Tain Yeh

Antimicrob Agents Chemother· July 2006

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Conversion of viramidine to ribavirin in vivo by adenosine deaminase and its inhibition by 2'-deoxycoformycin.
Jim Zhen Wu, Li-Tain Yeh, Chin-Chung Lin, Zhi Hong

Antivir Chem Chemother· May 2006

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Sensitive and specific LC-MS/MS method for the simultaneous measurements of viramidine and ribavirin in human plasma.
Yifei Liu, Christine Xu, Rongzi Yan, Charmaine Lim, Li-Tain Yeh

J Chromatogr B Analyt Technol Biomed Life Sci· February 2006

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Pharmacokinetics of pradefovir and PMEA in healthy volunteers after oral dosing of pradefovir.
Chin-chung Lin, Christine Xu, Alice Teng, Li-Tain Yeh, Janet Peterson

J Clin Pharmacol· November 2005

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A sensitive and specific method for the determination of total ribavirin in monkey liver by high-performance liquid chromatography with tandem mass spectrometry.
Li-Tain Yeh, Mai Nguyen, David Lourenco, Chin-Chung Lin

J Pharm Biomed Anal· June 2005

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Ascending multiple-dose pharmacokinetics of viramidine, a prodrug of ribavirin, in adult subjects with compensated hepatitis C infection.
Sanjee Aora, Christine Xu, Alice Teng, Janet Peterson, Li-Tain Yeh

J Clin Pharmacol· March 2005

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Single-dose pharmacokinetics and metabolism of [14C]remofovir in rats and cynomolgus monkeys.
Chin-Chung Lin, Christine Xu, Nanqun Zhu, David Lourenco, Li-Tain Yeh

Antimicrob Agents Chemother· March 2005

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