Publications by authors named "Livia Vivas"

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Favorable Preclinical Pharmacological Profile of a Novel Antimalarial Pyrrolizidinylmethyl Derivative of 4-amino-7-chloroquinoline with Potent In Vitro and In Vivo Activities.
Nicoletta Basilico, Silvia Parapini, Sarah D'Alessandro, Paola Misiano, Sergio Romeo, Livia Vivas

Biomolecules· May 2023

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In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial.
Nicoletta Basilico, Silvia Parapini, Anna Sparatore, Sergio Romeo, Paola Misiano, Livia Vivas

Molecules· December 2017

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Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
Richard K Amewu, James Chadwick, Afthab Hussain, Somnath Panda, Rinki Rinki, Livia Vivas

Bioorg Med Chem· December 2013

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Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target.
Ina L Lauinger, Livia Vivas, Remo Perozzo, Christopher Stairiker, Alice Tarun

J Nat Prod· June 2013

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Hepatitis B Co-Infection is Associated with Poorer Survival of HIV-Infected Patients on Highly Active Antiretroviral Therapy in West Africa.
Nimzing G Ladep, Oche O Agbaji, Patricia A Agaba, Auwal Muazu, Placid Ugoagwu, Livia Vivas

J AIDS Clin Res· June 2013

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Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target.
Yongyuth Yuthavong, Bongkoch Tarnchompoo, Tirayut Vilaivan, Penchit Chitnumsub, Sumalee Kamchonwongpaisan, Livia Vivas

Proc Natl Acad Sci U S A· October 2012

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Curcumin enhances non-opsonic phagocytosis of Plasmodium falciparum through up-regulation of CD36 surface expression on monocytes/macrophages.
Patrice N Mimche, Eloise Thompson, Donatella Taramelli, Livia Vivas

J Antimicrob Chemother· August 2012

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Indolone-N-oxide derivatives: in vitro activity against fresh clinical isolates of Plasmodium falciparum, stage specificity and in vitro interactions with established antimalarial drugs.
Rachida Tahar, Livia Vivas, Leonardo Basco, Eloise Thompson, Hany Ibrahim

J Antimicrob Chemother· November 2011

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Antiplasmodial and cytotoxicity evaluation of 3-functionalized 2-azetidinone derivatives.
Pardeep Singh, Shaveta Sachdeva, Raghu Raj, Vipan Kumar, Mohinder P Mahajan, Livia Vivas

Bioorg Med Chem Lett· August 2011

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The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria.
Patrice N Mimche, Donatella Taramelli, Livia Vivas

Malar J· March 2011

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Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.
Paul M O'Neill, Richard K Amewu, Gemma L Nixon, Fatima Bousejra ElGarah, Mathirut Mungthin, Livia Vivas

Angew Chem Int Ed Engl· August 2010

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Synthesis, in vitro and in vivo antimalarial assessment of sulfide, sulfone and vinyl amide-substituted 1,2,4-trioxanes prepared via thiol-olefin co-oxygenation (TOCO) of allylic alcohols.
Richard Amewu, Peter Gibbons, Amira Mukhtar, Andrew V Stachulski, Stephen A Ward, Livia Vivas

Org Biomol Chem· May 2010

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Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.
Bénédicte Pacorel, Suet C Leung, Andrew V Stachulski, Jill Davies, Livia Vivas

J Med Chem· January 2010

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Synthesis and antiplasmodial activity of new indolone N-oxide derivatives.
Françoise Nepveu, Sothea Kim, Jeremie Boyer, Olivier Chatriant, Hany Ibrahim, Livia Vivas

J Med Chem· January 2010

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Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
Paul M O'Neill, Alison E Shone, Deborah Stanford, Gemma Nixon, Eghbaleh Asadollahy, Livia Vivas

J Med Chem· April 2009

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Antioxidant C-glucosylxanthones from the leaves of Arrabidaea patellifera.
Frédéric Martin, Anne-Emmanuelle Hay, Delphine Cressend, Marianne Reist, Livia Vivas

J Nat Prod· November 2008

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Synthesis and structure-activity relationship of 3-phenylquinoxaline 1,4-di-N-oxide derivatives as antimalarial agents.
Esther Vicente, Lidia M Lima, Emily Bongard, Sarah Charnaud, Raquel Villar, Livia Vivas

Eur J Med Chem· September 2008

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Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.
Gemma L Ellis, Richard Amewu, Sunil Sabbani, Paul A Stocks, Alison Shone, Livia Vivas

J Med Chem· April 2008

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Hyperreactive malarial splenomegaly is associated with low levels of antibodies against red blood cell and Plasmodium falciparum derived glycolipids in Yanomami Amerindians from Venezuela.
Livia Vivas, Kieran P O'Dea, Oscar Noya, Rosalba Pabon, Magda Magris

Acta Trop· March 2008

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Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo.
Livia Vivas, Lauren Rattray, Lindsay Stewart, Emily Bongard, Brian L Robinson

Acta Trop· March 2008

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In vitro anti-malarial activity of N6-modified purine analogs.
Kathleen Too, Daniel M Brown, David Loakes, Emily Bongard, Livia Vivas

Nucleosides Nucleotides Nucleic Acids· February 2008

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Synthesis and antiplasmodial activity of 3-furyl and 3-thienylquinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives.
Esther Vicente, Sarah Charnaud, Emily Bongard, Raquel Villar, Asunción Burguete, Livia Vivas

Molecules· January 2008

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Preparation of N-sulfonyl- and N-carbonyl-11-azaartemisinins with greatly enhanced thermal stabilities: in vitro antimalarial activities.
Richard K Haynes, Ho-Ning Wong, Kin-Wo Lee, Chung-Man Lung, Lai Yung Shek, Livia Vivas

ChemMedChem· October 2007

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Anti-malarial activity of N6-modified purine analogues.
Kathleen Too, Daniel M Brown, Emily Bongard, Vanessa Yardley, Livia Vivas

Bioorg Med Chem· August 2007

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Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin.
Richard Amewu, Andrew V Stachulski, Stephen A Ward, Neil G Berry, Patrick G Bray, Livia Vivas

Org Biomol Chem· December 2006

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