Publications by authors named "Loretta Dorstyn"

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Understanding Developmental Cell Death Using as a Model System.
Ruchi Umargamwala, Jantina Manning, Loretta Dorstyn, Donna Denton, Sharad Kumar

Cells· February 2024

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The role of caspases as executioners of apoptosis.
Sharad Kumar, Loretta Dorstyn, Yoon Lim

Biochem Soc Trans· February 2022

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The p53-caspase-2 axis in the cell cycle and DNA damage response.
Yoon Lim, Loretta Dorstyn, Sharad Kumar

Exp Mol Med· April 2021

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Phosphorylation by Aurora B kinase regulates caspase-2 activity and function.
Yoon Lim, Dylan De Bellis, Jarrod J Sandow, Luisa Capalbo, Pier Paolo D'Avino, Loretta Dorstyn

Cell Death Differ· January 2021

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The 9th Barossa Meeting: Cell Signalling in Cancer Medicine.
Loretta Dorstyn, Denis Tvorogov, Shiva Malek, Nirmal Robinson

Cell Death Dis· March 2020

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Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling.
Loretta Dorstyn, Emily Hackett-Jones, Andrej Nikolic, Murray D Norris, Yoon Lim

Cell Death Dis· January 2019

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p53 accumulation following cytokinesis failure in the absence of caspase-2.
Yoon Lim, Dylan De Bellis, Loretta Dorstyn, Sharad Kumar

Cell Death Differ· November 2018

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New insights into apoptosome structure and function.
Loretta Dorstyn, Christopher W Akey, Sharad Kumar

Cell Death Differ· July 2018

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Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity.
Claire H Wilson, Andrej Nikolic, Stephen J Kentish, Marianne Keller, George Hatzinikolas, Loretta Dorstyn

Cell Death Dis· October 2017

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Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice.
Swati Dawar, Nur Hezrin Shahrin, Nikolina Sladojevic, Richard J D'Andrea, Loretta Dorstyn

Cell Death Dis· December 2016

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Caspase-2 protocols.
Loretta Dorstyn, Sharad Kumar

Methods Mol Biol· October 2014

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Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice.
Joseph Puccini, Sonia Shalini, Anne K Voss, Magtouf Gatei, Claire H Wilson, Loretta Dorstyn

Proc Natl Acad Sci U S A· December 2013

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Tumour necrosis factor alpha (TNF-alpha) stimulation of cells with established dengue virus type 2 infection induces cell death that is accompanied by a reduced ability of TNF-alpha to activate nuclear factor kappaB and reduced sphingosine kinase-1 activity.
Satiya Wati, Stephen M Rawlinson, Ruby A Ivanov, Loretta Dorstyn, Michael R Beard

J Gen Virol· April 2011

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Ndfip1-deficient mice have impaired DMT1 regulation and iron homeostasis.
Natalie J Foot, Yew Ann Leong, Loretta E Dorstyn, Hazel E Dalton, Kristen Ho

Blood· January 2011

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Structure of the Drosophila apoptosome at 6.9 å resolution.
Shujun Yuan, Xinchao Yu, Maya Topf, Loretta Dorstyn, Sharad Kumar

Structure· January 2011

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Putative functions of caspase-2.
Loretta Dorstyn, Sharad Kumar

F1000 Biol Rep· December 2009

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Analysing caspase activation and caspase activity in apoptotic cells.
Sharad Kumar, Loretta Dorstyn

Methods Mol Biol· October 2009

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Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons.
Jason Howitt, Ulrich Putz, Jenny Lackovic, Anh Doan, Loretta Dorstyn

Proc Natl Acad Sci U S A· September 2009

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A tumor suppressor function for caspase-2.
Lien Ha Ho, Robyn Taylor, Loretta Dorstyn, Dimitrios Cakouros, Philippe Bouillet

Proc Natl Acad Sci U S A· March 2009

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Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2.
Natalie J Foot, Hazel E Dalton, Linda M Shearwin-Whyatt, Loretta Dorstyn, Seong-Seng Tan

Blood· November 2008

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The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells.
Loretta Dorstyn, Kathryn Mills, Yuri Lazebnik, Sharad Kumar

J Cell Biol· November 2004

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The role of cytochrome c in caspase activation in Drosophila melanogaster cells.
Loretta Dorstyn, Stuart Read, Dimitrios Cakouros, Jun R Huh, Bruce A Hay

J Cell Biol· March 2002

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