Publications by authors named "MJ Dresser"

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A clinical drug-drug interaction study to evaluate the effect of a proton-pump inhibitor, a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor, and a CYP2C9 inhibitor on the pharmacokinetics of vismodegib.
Vikram Malhi, Dawn Colburn, Sarah J Williams, Cornelis E C A Hop, Mark J Dresser

Cancer Chemother Pharmacol· July 2016

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Best practices for the use of itraconazole as a replacement for ketoconazole in drug-drug interaction studies.
Lichuan Liu, Akintunde Bello, Mark J Dresser, Donald Heald, Steven Ferenc Komjathy

J Clin Pharmacol· February 2016

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Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans.
Ryan H Takahashi, Edna F Choo, Shuguang Ma, Susan Wong, Jason Halladay, Mark J Dresser

Drug Metab Dispos· January 2016

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The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria.
Marc R Yago, Adam Frymoyer, Leslie Z Benet, Gillian S Smelick, Lynda A Frassetto, Mark J Dresser

AAPS J· November 2014

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Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydria.
Marc R Yago, Adam R Frymoyer, Gillian S Smelick, Lynda A Frassetto, Nageshwar R Budha, Mark J Dresser

Mol Pharm· November 2013

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Absolute bioavailability and effect of formulation change, food, or elevated pH with rabeprazole on cobimetinib absorption in healthy subjects.
Luna Musib, Edna Choo, Yuzhong Deng, Steve Eppler, Isabelle Rooney, Mark J Dresser

Mol Pharm· November 2013

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Prevalence of acid-reducing agents (ARA) in cancer populations and ARA drug-drug interaction potential for molecular targeted agents in clinical development.
Gillian S Smelick, Timothy P Heffron, Laura Chu, Brian Dean, David A West, Mark J Dresser

Mol Pharm· November 2013

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Impact of food and the proton pump inhibitor rabeprazole on the pharmacokinetics of GDC-0941 in healthy volunteers: bench to bedside investigation of pH-dependent solubility.
Joseph A Ware, Gena Dalziel, Jin Y Jin, Jackson D Pellett, Gillian S Smelick, Mark J Dresser

Mol Pharm· November 2013

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A physiologically based pharmacokinetic (PBPK) approach to evaluate pharmacokinetics in patients with cancer.
Sravanthi Cheeti, Nageshwar R Budha, Sharmila Rajan, Mark J Dresser, Jin Y Jin

Biopharm Drug Dispos· April 2013

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Daily dosing of vismodegib to steady state does not prolong the QTc interval in healthy volunteers.
Richard A Graham, Ilsung Chang, Jin Yan Jin, Bei Wang, Matthew B Dufek, Mark J Dresser

J Cardiovasc Pharmacol· January 2013

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Single and multiple dose intravenous and oral pharmacokinetics of the hedgehog pathway inhibitor vismodegib in healthy female subjects.
Richard A Graham, Cornelis E C A Hop, Marie T Borin, Bert L Lum, Dawn Colburn, Mark J Dresser

Br J Clin Pharmacol· November 2012

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Drug absorption interactions between oral targeted anticancer agents and PPIs: is pH-dependent solubility the Achilles heel of targeted therapy?
N R Budha, A Frymoyer, G S Smelick, J Y Jin, M R Yago, M J Dresser

Clin Pharmacol Ther· August 2012

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A guide to rational dosing of monoclonal antibodies.
Shuang Bai, Karin Jorga, Yan Xin, Denise Jin, Yanan Zheng, Mark J Dresser

Clin Pharmacokinet· February 2012

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Pharmacokinetics of dapoxetine, a new treatment for premature ejaculation: Impact of age and effects of a high-fat meal.
Mark J Dresser, Dongwoo Kang, Peter Staehr, Shalini Gidwani, Cindy Guo

J Clin Pharmacol· September 2006

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Dapoxetine, a novel treatment for premature ejaculation, does not have pharmacokinetic interactions with phosphodiesterase-5 inhibitors.
M J Dresser, D Desai, S Gidwani, A D Seftel, N B Modi

Int J Impot Res· June 2006

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Single- and multiple-dose pharmacokinetics of dapoxetine hydrochloride, a novel agent for the treatment of premature ejaculation.
Nishit B Modi, Mark J Dresser, Mary Simon, Denise Lin, Dhaval Desai

J Clin Pharmacol· March 2006

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Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT.
Karin M Gerstin, Mark J Dresser, Kathleen M Giacomini

Am J Physiol Renal Physiol· August 2002

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Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2).
Mark J Dresser, Guangqing Xiao, Maya K Leabman, Andrew T Gray, Kathleen M Giacomini

Pharm Res· August 2002

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The potency of new muscle relaxants on recombinant muscle-type acetylcholine receptors.
Matthias Paul, Christoph H Kindler, Ralf M Fokt, Mark J Dresser, Natalie C J Dipp

Anesth Analg· March 2002

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The MDR1 C3435T polymorphism: effects on P-glycoprotein expression/function and clinical significance.
M J Dresser

AAPS PharmSci· February 2002

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Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3.
B Feng, M J Dresser, Y Shu, S J Johns, K M Giacomini

Biochemistry· May 2001

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Transporters involved in the elimination of drugs in the kidney: organic anion transporters and organic cation transporters.
M J Dresser, M K Leabman, K M Giacomini

J Pharm Sci· April 2001

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Electrophysiological analysis of the substrate selectivity of a sodium-coupled nucleoside transporter (rCNT1) expressed in Xenopus laevis oocytes.
M J Dresser, K M Gerstin, A T Gray, D D Loo, K M Giacomini

Drug Metab Dispos· September 2000

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Molecular cloning of a Na+-dependent nucleoside transporter from rabbit intestine.
K M Gerstin, M J Dresser, J Wang, K M Giacomini

Pharm Res· August 2000

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Molecular and functional characteristics of cloned human organic cation transporters.
M J Dresser, L Zhang, K M Giacomini

Pharm Biotechnol· May 2000

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