Publications by authors named "Malcolm D Smith"

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A genome-wide association analysis reveals new pathogenic pathways in gout.
Tanya J Major, Riku Takei, Hirotaka Matsuo, Megan P Leask, Nicholas A Sumpter, Malcolm D Smith

Nat Genet· November 2024

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Publisher Correction: A genome-wide association analysis reveals new pathogenic pathways in gout.
Tanya J Major, Riku Takei, Hirotaka Matsuo, Megan P Leask, Nicholas A Sumpter, Malcolm D Smith

Nat Genet· November 2024

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Transcriptomic profiling of programmed cell death 1 (PD-1) expressing T cells in early rheumatoid arthritis identifies a decreased CD4 + PD-1 + signature post-treatment.
Katie Lowe, Annabelle Small, Qingxuan Song, Ling-Yang Hao, William Murray-Brown, Malcolm D Smith

Sci Rep· February 2023

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Differential expansion of T peripheral helper cells in early rheumatoid arthritis and osteoarthritis synovium.
William Murray-Brown, Yanxia Guo, Annabelle Small, Katie Lowe, Helen Weedon, Malcolm D Smith

RMD Open· October 2022

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Nivolumab-induced synovitis is characterized by florid T cell infiltration and rapid resolution with synovial biopsy-guided therapy.
William Murray-Brown, Tom D Wilsdon, Helen Weedon, Susanna Proudman, Shawgi Sukumaran, Malcolm D Smith

J Immunother Cancer· June 2020

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Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus.
Suzanne Cole, Alice Walsh, Xuefeng Yin, Mihir D Wechalekar, Malcolm D Smith

Arthritis Res Ther· May 2018

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Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.
Yanxia Guo, Alice M Walsh, Mary Canavan, Mihir D Wechalekar, Suzanne Cole, Malcolm D Smith

PLoS One· April 2018

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Opposing effects of rheumatoid arthritis and low dose prednisolone on arginine metabolomics.
Anjana Radhakutty, Brenda L Mangelsdorf, Sophie M Drake, Andrew Rowland, Malcolm D Smith

Atherosclerosis· November 2017

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Osteoclast-Associated Receptor (OSCAR) Distribution in the Synovial Tissues of Patients with Active RA and TNF-α and RANKL Regulation of Expression by Osteoclasts In Vitro.
Anak A S S K Dharmapatni, Kent Algate, Roxanne Coleman, Michelle Lorimer, Melissa D Cantley, Malcolm D Smith

Inflammation· October 2017

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Triple DMARD treatment in early rheumatoid arthritis modulates synovial T cell activation and plasmablast/plasma cell differentiation pathways.
Alice M Walsh, Mihir D Wechalekar, Yanxia Guo, Xuefeng Yin, Helen Weedon, Malcolm D Smith

PLoS One· October 2017

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CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression.
Yanxia Guo, Alice M Walsh, Ursula Fearon, Malcolm D Smith, Mihir D Wechalekar

J Immunol· June 2017

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A Treat-to-Target Strategy Preserves Work Capacity in a Rheumatoid Arthritis Inception Cohort Treated With Combination Conventional DMARD Therapy.
Mihir D Wechalekar, Stephen Quinn, Susan Lester, Robert G Metcalf, Ella Shanahan, Malcolm D Smith

J Clin Rheumatol· April 2017

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Low dose prednisolone and insulin sensitivity differentially affect arterial stiffness and endothelial function: An open interventional and cross-sectional study.
Carolyn J Petersons, Brenda L Mangelsdorf, Anne Poljak, Malcolm D Smith, Jerry R Greenfield

Atherosclerosis· March 2017

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Arthroscopic guided synovial biopsy in rheumatology: current perspectives.
Mihir D Wechalekar, Malcolm D Smith

Int J Rheum Dis· February 2017

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Effects of prednisolone on energy and fat metabolism in patients with rheumatoid arthritis: tissue-specific insulin resistance with commonly used prednisolone doses.
Anjana Radhakutty, Brenda L Mangelsdorf, Sophie M Drake, Dorit Samocha-Bonet, Leonie K Heilbronn, Malcolm D Smith

Clin Endocrinol (Oxf)· November 2016

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Active Foot Synovitis in Patients With Rheumatoid Arthritis: Unstable Remission Status, Radiographic Progression, and Worse Functional Outcomes in Patients With Foot Synovitis in Apparent Remission.
Mihir D Wechalekar, Susan Lester, Catherine L Hill, Anita Lee, Maureen Rischmueller, Malcolm D Smith

Arthritis Care Res (Hoboken)· November 2016

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Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout.
Humaira Rasheed, Amanda J Phipps-Green, Ruth Topless, Malcolm D Smith, Catherine Hill

Rheumatology (Oxford)· August 2016

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The X-Linked Inhibitor of Apoptosis Protein Inhibitor Embelin Suppresses Inflammation and Bone Erosion in Collagen Antibody Induced Arthritis Mice.
Anak A S S K Dharmapatni, Melissa D Cantley, Victor Marino, Egon Perilli, Tania N Crotti, Malcolm D Smith

Mediators Inflamm· June 2016

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Effect of acute and chronic glucocorticoid therapy on insulin sensitivity and postprandial vascular function.
Anjana Radhakutty, Brenda L Mangelsdorf, Sophie M Drake, Dorit Samocha-Bonet, Arthur B Jenkins, Malcolm D Smith

Clin Endocrinol (Oxf)· April 2016

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PTPN22 R620W minor allele is a genetic risk factor for giant cell arteritis.
Susan Lester, Alex W Hewitt, Carlee D Ruediger, Linda Bradbury, Elisabeth De Smit, Malcolm D Smith

RMD Open· April 2016

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Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter--Determining Validation Requirements.
Frances Humby, Stephen Kelly, Serena Bugatti, Antonio Manzo, Andrew Filer, Malcolm D Smith

J Rheumatol· January 2016

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ACP Journal Club. Review: Methotrexate does not increase risk for lung disease in psoriasis, psoriatic arthritis, or IBD.
Malcolm D Smith

Ann Intern Med· July 2015

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Utility of arthroscopic guided synovial biopsy in understanding synovial tissue pathology in health and disease states.
Mihir D Wechalekar, Malcolm D Smith

World J Orthop· November 2014

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Greater trochanteric pain syndrome: does imaging-identified pathology influence the outcome of interventions?
Shayne A Wilson, Ernst M Shanahan, Malcolm D Smith

Int J Rheum Dis· July 2014

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Effects of low-dose prednisolone on hepatic and peripheral insulin sensitivity, insulin secretion, and abdominal adiposity in patients with inflammatory rheumatologic disease.
Carolyn J Petersons, Brenda L Mangelsdorf, Arthur B Jenkins, Anne Poljak, Malcolm D Smith

Diabetes Care· September 2013

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