Publications by authors named "Manfred Gessler"

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Advancing sarcoma diagnostics with expanded DNA methylation-based classification.
Natalie Jäger, David E Reuss, Martin Sill, Daniel Schrimpf, Abigail K Suwala, Manfred Gessler

medRxiv· June 2025

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Distinct pathways for genetic and epigenetic predisposition in familial and bilateral Wilms tumor.
Jenny Wegert, Silke Appenzeller, Taryn D Treger, Heike Streitenberger, Barbara Ziegler, Manfred Gessler

Genome Med· May 2025

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High resolution clonal architecture of hypomutated Wilms tumours.
Henry Lee-Six, Taryn D Treger, Manas Dave, Tim Hh Coorens, Nathaniel D Anderson, Manfred Gessler

Nat Commun· May 2025

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The Clinical Impact of Somatic Copy Number Variations in Patients With Stage IV Wilms Tumor Enrolled in the SIOP 2001 Trial and Study.
Nils Welter, Reem Al-Saadi, Robinson Gravier-Dumonceau, Rhoikos Furtwängler, Norbert Graf, Manfred Gessler

Pediatr Blood Cancer· April 2025

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Predisposition Footprints in the Somatic Genome of Wilms Tumors.
Taryn D Treger, Jenny Wegert, Anna Wenger, Tim H H Coorens, Reem Al-Saadi, Manfred Gessler

Cancer Discov· February 2025

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Wilms tumor primary cultures capture phenotypic heterogeneity and facilitate preclinical screening.
Lisa Götz, Jenny Wegert, Alireza Paikari, Silke Appenzeller, Sabrina Bausenwein, Manfred Gessler

Transl Oncol· February 2025

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Characteristics and outcome of synchronous bilateral Wilms tumour in the SIOP WT 2001 Study: Report from the SIOP Renal Tumour Study Group (SIOP-RTSG).
Hélène Sudour-Bonnange, Harm van Tinteren, Gema L Ramírez-Villar, Jan Godzinski, Sabine Irtan, Manfred Gessler

Br J Cancer· October 2024

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How to improve initial diagnostic accuracy of kidney tumours in childhood?-A non-invasive approach.
Nils Welter, Gregor Metternich, Rhoikos Furtwängler, Ahmed Bayoumi, Marvin Mergen, Manfred Gessler

Int J Cancer· June 2024

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The impact of the route to diagnosis in nephroblastoma.
Marvin Mergen, Nils Welter, Rhoikos Furtwängler, Patrick Melchior, Christian Vokuhl, Manfred Gessler

Cancer Med· May 2024

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Hallmark discoveries in the biology of Wilms tumour.
Daniela Perotti, Richard D Williams, Jenny Wegert, Jack Brzezinski, Mariana Maschietto, Manfred Gessler

Nat Rev Urol· March 2024

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TRIM28 inactivation in epithelial nephroblastoma is frequent and often associated with predisposing TRIM28 germline variants.
Jenny Wegert, Anne Kristin Fischer, Balazs Palhazi, Taryn D Treger, Cäcilia Hilgers, Manfred Gessler

J Pathol· January 2024

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Tumor biology, biomarkers, and liquid biopsy in pediatric renal tumors.
Amy L Walz, Mariana Maschietto, Brian Crompton, Nicholas Evageliou, David Dix, Manfred Gessler

Pediatr Blood Cancer· May 2023

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Genomic characterization of DICER1-associated neoplasms uncovers molecular classes.
Felix K F Kommoss, Anne-Sophie Chong, Anne-Laure Chong, Elke Pfaff, David T W Jones, Manfred Gessler

Nat Commun· March 2023

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The genomic landscape of pediatric renal cell carcinomas.
Pengbo Beck, Barbara Selle, Lukas Madenach, David T W Jones, Christian Vokuhl, Manfred Gessler

iScience· April 2022

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The DGCR8 E518K mutation found in Wilms tumors leads to a partial miRNA processing defect that alters gene expression patterns and biological processes.
Romina Vardapour, Tim Kehl, Susanne Kneitz, Nicole Ludwig, Eckart Meese, Manfred Gessler

Carcinogenesis· March 2022

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Correction: Welter et al. Characteristics of Nephroblastoma/Nephroblastomatosis in Children with a Clinically Reported Underlying Malformation or Cancer Predisposition Syndrome. 2021, , 5016.
Nils Welter, Angelo Wagner, Rhoikos Furtwängler, Patrick Melchior, Leo Kager, Manfred Gessler

Cancers (Basel)· November 2021

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Characteristics of Nephroblastoma/Nephroblastomatosis in Children with a Clinically Reported Underlying Malformation or Cancer Predisposition Syndrome.
Nils Welter, Angelo Wagner, Rhoikos Furtwängler, Patrick Melchior, Leo Kager, Manfred Gessler

Cancers (Basel)· October 2021

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Wilms tumour.
Filippo Spreafico, Conrad V Fernandez, Jesper Brok, Kayo Nakata, Gordan Vujanic, Manfred Gessler

Nat Rev Dis Primers· October 2021

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MYCN and MAX alterations in Wilms tumor and identification of novel N-MYC interaction partners as biomarker candidates.
Ovidio Jiménez Martín, Andreas Schlosser, Rhoikos Furtwängler, Jenny Wegert, Manfred Gessler

Cancer Cell Int· October 2021

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Characteristics and outcome of pediatric renal cell carcinoma patients registered in the International Society of Pediatric Oncology (SIOP) 93-01, 2001 and UK-IMPORT database: A report of the SIOP-Renal Tumor Study Group.
Justine N van der Beek, Janna A Hol, Aurore Coulomb-l'Hermine, Norbert Graf, Harm van Tinteren, Manfred Gessler

Int J Cancer· June 2021

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Sarcoma classification by DNA methylation profiling.
Christian Koelsche, Daniel Schrimpf, Damian Stichel, Martin Sill, Felix Sahm, Manfred Gessler

Nat Commun· January 2021

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HEYL Regulates Neoangiogenesis Through Overexpression in Both Breast Tumor Epithelium and Endothelium.
Liangfeng Han, Preethi Korangath, Nguyen K Nguyen, Adam Diehl, Soonweng Cho, Manfred Gessler

Front Oncol· January 2021

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Less may be more for stage I epithelial Wilms tumors.
Manfred Gessler, Norbert Graf

Cancer· June 2020

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High-risk blastemal Wilms tumor can be modeled by 3D spheroid cultures in vitro.
Jenny Wegert, Lisa Zauter, Silke Appenzeller, Christoph Otto, Sabrina Bausenwein, Manfred Gessler

Oncogene· January 2020

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Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration.
Hye-Jung E Chun, Pascal D Johann, Katy Milne, Marc Zapatka, Annette Buellesbach, Manfred Gessler

Cell Rep· November 2019

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