Publications by authors named "Manlio Palumbo"

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Selective Ligands for Non-Canonical DNA Structures: Do They Have a Future in Medicinal Chemistry?
Manlio Palumbo, Claudia Sissi

Int J Mol Sci· October 2022

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Bench to bedside: The ambitious goal of transducing medicinal chemistry from the lab to the clinic.
Manlio Palumbo, Claudia Sissi

Bioorg Med Chem Lett· August 2022

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Targeting Canine Promoter by Candidate DNA G-Quadruplex Ligands.
Eleonora Zorzan, Silvia Da Ros, Mery Giantin, Lara Zorro Shahidian, Giorgia Guerra, Manlio Palumbo

J Pharmacol Exp Ther· December 2018

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Highly Improved Electrospray Ionization-Mass Spectrometry Detection of G-Quadruplex-Folded Oligonucleotides and Their Complexes with Small Molecules.
Matteo Scalabrin, Manlio Palumbo, Sara N Richter

Anal Chem· September 2017

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Discovery of RET and RET Inhibitors: From Hit to Lead.
Luca Mologni, Martina Dalla Via, Adriana Chilin, Manlio Palumbo, Giovanni Marzaro

ChemMedChem· August 2017

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The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids.
Sara Lago, Elena Tosoni, Matteo Nadai, Manlio Palumbo, Sara N Richter

Biochim Biophys Acta Gen Subj· May 2017

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G-quadruplexes in human promoters: A challenge for therapeutic applications.
Riccardo Rigo, Manlio Palumbo, Claudia Sissi

Biochim Biophys Acta Gen Subj· May 2017

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Virtual Cross-Linking of the Active Nemorubicin Metabolite PNU-159682 to Double-Stranded DNA.
Matteo Scalabrin, Luigi Quintieri, Manlio Palumbo, Federico Riccardi Sirtori, Barbara Gatto

Chem Res Toxicol· February 2017

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Molecular Basis for Differential Recognition of G-Quadruplex versus Double-Helix DNA by Bis-Phenanthroline Metal Complexes.
Riccardo Rigo, Sara Bianco, Caterina Musetti, Manlio Palumbo, Claudia Sissi

ChemMedChem· August 2016

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Screening of candidate G-quadruplex ligands for the human c-KIT promotorial region and their effects in multiple in-vitro models.
Eleonora Zorzan, Silvia Da Ros, Caterina Musetti, Lara Zorro Shahidian, Nuno Filipe Ramos Coelho, Manlio Palumbo

Oncotarget· April 2016

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Inflammatory cytokine expression following the use of bipolar electrocoagulation, ultracision harmonic scalpel and cold knife biopsy.
Pietro Litta, Carlo Saccardi, Salvatore Gizzo, Lorena Conte, Giulia Ambrosi, Manlio Palumbo

Mol Med Rep· August 2015

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Telomeric G-quadruplex architecture and interactions with potential drugs.
Claudia Sissi, Manlio Palumbo

Curr Pharm Des· June 2015

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Sequencing and G-quadruplex folding of the canine proto-oncogene KIT promoter region: might dog be used as a model for human disease?
Silvia Da Ros, Eleonora Zorzan, Mery Giantin, Lara Zorro Shahidian, Manlio Palumbo

PLoS One· April 2015

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Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: in vitro antiproliferative activity and molecular mechanism(s) of action.
Barbara Parrino, Anna Carbone, Cristina Ciancimino, Virginia Spanò, Alessandra Montalbano, Manlio Palumbo

Eur J Med Chem· April 2015

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Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity.
Barbara Parrino, Anna Carbone, Virginia Spanò, Alessandra Montalbano, Daniele Giallombardo, Manlio Palumbo

Eur J Med Chem· April 2015

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Assessment of gene promoter G‑quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells.
Matteo Nadai, Graziella Cimino-Reale, Giovanna Sattin, Filippo Doria, Elena Butovskaya, Manlio Palumbo

Int J Oncol· January 2015

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Conformation and stability of intramolecular telomeric G-quadruplexes: sequence effects in the loops.
Giovanna Sattin, Anna Artese, Matteo Nadai, Giosuè Costa, Lucia Parrotta, Manlio Palumbo

PLoS One· October 2014

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Novel ametantrone-amsacrine related hybrids as topoisomerase IIβ poisons and cytotoxic agents.
Giuseppe Zagotto, Alessandra Gianoncelli, Claudia Sissi, Cristina Marzano, Valentina Gandin, Manlio Palumbo

Arch Pharm (Weinheim)· October 2014

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Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity.
Rosalba Perrone, Matteo Nadai, Jerrod A Poe, Ilaria Frasson, Manlio Palumbo

PLoS One· March 2014

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Clerocidin-mediated DNA footprinting discriminates among different G-quadruplex conformations and detects tetraplex folding in a duplex environment.
Matteo Nadai, Giovanna Sattin, Giorgio Palù, Manlio Palumbo, Sara N Richter

Biochim Biophys Acta· October 2013

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Effect of G-quadruplex polymorphism on the recognition of telomeric DNA by a metal complex.
Caterina Musetti, A Paul Krapcho, Manlio Palumbo, Claudia Sissi

PLoS One· September 2013

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Ni2+ and Cu2+ complexes of a phenanthroline-based ligand bind to G-quadruplexes at non-overlapping sites.
Sara Bianco, Caterina Musetti, A Paul Krapcho, Manlio Palumbo, Claudia Sissi

Chem Commun (Camb)· September 2013

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A dynamic G-quadruplex region regulates the HIV-1 long terminal repeat promoter.
Rosalba Perrone, Matteo Nadai, Ilaria Frasson, Jerrod A Poe, Elena Butovskaya, Manlio Palumbo

J Med Chem· August 2013

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Differential targeting of unpaired bases within duplex DNA by the natural compound clerocidin: a valuable tool to dissect DNA secondary structure.
Matteo Nadai, Giorgio Palù, Manlio Palumbo, Sara N Richter

PLoS One· July 2013

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Metal ion and inter-domain interactions as functional networks in E. coli topoisomerase I.
Claudia Sissi, Bokun Cheng, Valentina Lombardo, Yuk-Ching Tse-Dinh, Manlio Palumbo

Gene· July 2013

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