Publications by authors named "Manolo Bellotto"

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Allosteric Modulation of GCase Enhances Lysosomal Activity and Reduces ER Stress in GCase-Related Disorders.
Ilaria Fregno, Natalia Pérez-Carmona, Mikhail Rudinskiy, Tatiana Soldà, Timothy J Bergmann, Manolo Bellotto

Int J Mol Sci· May 2025

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A novel allosteric GCase modulator prevents Tau accumulation in GBA1 and GBA1 cellular models.
Matteo Ciccaldo, Natàlia Pérez-Carmona, Ester Piovesana, Sara Cano-Crespo, Ana Ruano, Manolo Bellotto

Sci Rep· May 2025

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Developing Allosteric Chaperones for -Associated Disorders-An Integrated Computational and Experimental Approach.
Marta Montpeyo, Natàlia Pérez-Carmona, Elena Cubero, Aida Delgado, Ana Ruano, Manolo Bellotto

Int J Mol Sci· December 2024

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Discovery of allosteric regulators with clinical potential to stabilize alpha-L-iduronidase in mucopolysaccharidosis type I.
Elena Cubero, Ana Ruano, Aida Delgado, Xavier Barril, Sara Morales, Manolo Bellotto

PLoS One· May 2024

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Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors.
Mikhail Rudinskiy, Maria Pons-Vizcarra, Tatiana Soldà, Ilaria Fregno, Timothy Jan Bergmann, Manolo Bellotto

PLoS One· December 2023

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Tau accumulation in degradative organelles is associated to lysosomal stress.
Ester Piovesana, Claudia Magrin, Matteo Ciccaldo, Martina Sola, Manolo Bellotto

Sci Rep· October 2023

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Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome.
Manolo Bellotto, Daniel Bopp, Kirsten A Senti, Richard Burke, Peter Deak

Int J Dev Biol· January 2002

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