Publications by authors named "Manuel Sepulveda"

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Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
Victor Moreno, Juan Manuel Sepúlveda, David A Reardon, Ángel Pérez-Núñez, Pedro González León

Neuro Oncol· June 2023

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Anti-tumor activity of a T-helper 1 multiantigen vaccine in a murine model of prostate cancer.
Denise L Cecil, Benjamin Curtis, Ekram Gad, Michael Gormley, Andrew E Timms, Manuel A Sepulveda

Sci Rep· August 2022

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Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine.
Mathieu Gigoux, Morten O Holmström, Roberta Zappasodi, Joseph J Park, Stephane Pourpe, Manuel A Sepulveda

Sci Transl Med· June 2022

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Cemeteries as sources of Aedes aegypti and other mosquito species in southeastern Puerto Rico.
Luisa M Otero, Gisela Medina-Martinez, Manuel Sepúlveda, Verónica Acevedo, Mayra Toro

Trop Med Int Health· March 2022

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Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice.
Filippo Veglia, Ayumi Hashimoto, Harsh Dweep, Emilio Sanseviero, Alessandra De Leo, Manuel A Sepulveda

J Exp Med· April 2021

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A phase II randomized, multicenter, open-label trial of continuing adjuvant temozolomide beyond 6 cycles in patients with glioblastoma (GEINO 14-01).
Carmen Balana, Maria Angeles Vaz, Juan Manuel Sepúlveda, Carlos Mesia, Sonia Del Barco

Neuro Oncol· December 2020

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Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors.
Vinit Kumar, Laxminarasimha Donthireddy, Douglas Marvel, Thomas Condamine, Fang Wang, Manuel A Sepulveda

Cancer Cell· November 2017

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VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer.
Jianjun Gao, John F Ward, Curtis A Pettaway, Lewis Z Shi, Sumit K Subudhi, Manuel A Sepulveda

Nat Med· May 2017

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Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients.
Thomas Condamine, George A Dominguez, Je-In Youn, Andrew V Kossenkov, Sridevi Mony, Manuel A Sepulveda

Sci Immunol· August 2016

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The DNA methylation profile of activated human natural killer cells.
John K Wiencke, Rondi Butler, George Hsuang, Melissa Eliot, Stephanie Kim, Manuel A Sepulveda

Epigenetics· May 2016

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High Resolution Viscosity Measurement by Thermal Noise Detection.
Felipe Aguilar Sandoval, Manuel Sepúlveda, Ludovic Bellon, Francisco Melo

Sensors (Basel)· November 2015

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Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor × c-MET Bispecific Antibody.
Stephen W Jarantow, Barbara S Bushey, Jose R Pardinas, Ken Boakye, Eilyn R Lacy, Manuel A Sepulveda

J Biol Chem· October 2015

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Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy.
Xiaozhou Fan, Sergio A Quezada, Manuel A Sepulveda, Padmanee Sharma, James P Allison

J Exp Med· April 2014

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Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.
Tyler R Simpson, Fubin Li, Welby Montalvo-Ortiz, Manuel A Sepulveda, Katharina Bergerhoff

J Exp Med· August 2013

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Cutting edge: chronic inflammatory liver disease in mice expressing a CD28-specific ligand.
Emily Corse, Rachel A Gottschalk, Joon Seok Park, Manuel A Sepulveda, P'ng Loke

J Immunol· January 2013

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Changes in replication, nuclear location, and expression of the Igh locus after fusion of a pre-B cell line with a T cell line.
Jie Zhou, Shireen Saleque, Olga Ermakova, Manuel A Sepulveda, Qiaoxin Yang

J Immunol· August 2005

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Comparative analysis of human and mouse 3' Igh regulatory regions identifies distinctive structural features.
Manuel A Sepulveda, Francine E Garrett, Alexa Price-Whelan, Barbara K Birshtein

Mol Immunol· March 2005

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Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites.
Francine E Garrett, Alexander V Emelyanov, Manuel A Sepulveda, Patrick Flanagan, Sabrina Volpi

Mol Cell Biol· February 2005

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NF-kappa B and Oct-2 synergize to activate the human 3' Igh hs4 enhancer in B cells.
Manuel A Sepulveda, Alexander V Emelyanov, Barbara K Birshtein

J Immunol· January 2004

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A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription.
Nickolai A Barlev, Alexander V Emelyanov, Paola Castagnino, Philip Zegerman, Andrew J Bannister, Manuel A Sepulveda

Mol Cell Biol· October 2003

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The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells.
Alexander V Emelyanov, Cecilia R Kovac, Manuel A Sepulveda, Barbara K Birshtein

J Biol Chem· March 2002

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