Publications by authors named "Marc Laruelle"

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Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain.
Nabeel B Nabulsi, Joël Mercier, Daniel Holden, Stephane Carré, Soheila Najafzadeh, Marc Laruelle

J Nucl Med· May 2016

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Human Kinetic Modeling of the 5HT6 PET Radioligand 11C-GSK215083 and Its Utility for Determining Occupancy at Both 5HT6 and 5HT2A Receptors by SB742457 as a Potential Therapeutic Mechanism of Action in Alzheimer Disease.
Christine A Parker, Eugenii A Rabiner, Roger N Gunn, Graham Searle, Laurent Martarello, Marc Laruelle

J Nucl Med· December 2015

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Characterization in humans of 18F-MNI-444, a PET radiotracer for brain adenosine 2A receptors.
Olivier Barret, Jonas Hannestad, Christine Vala, David Alagille, Adriana Tavares, Marc Laruelle

J Nucl Med· April 2015

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An evaluation of the brain distribution of [(11)C]GSK1034702, a muscarinic-1 (M 1) positive allosteric modulator in the living human brain using positron emission tomography.
Khanum Ridler, Vincent Cunningham, Mickael Huiban, Laurent Martarello, Sabina Pampols-Maso, Marc Laruelle

EJNMMI Res· December 2014

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Adenosine 2A receptor occupancy by tozadenant and preladenant in rhesus monkeys.
Olivier Barret, Jonas Hannestad, David Alagille, Christine Vala, Adriana Tavares, Marc Laruelle

J Nucl Med· October 2014

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Characterising the plasma-target occupancy relationship of the neurokinin antagonist GSK1144814 with PET.
Khanum Ridler, Roger N Gunn, Graham E Searle, Julien Barletta, Jan Passchier, Marc A Laruelle

J Psychopharmacol· March 2014

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Schizophrenia: from dopaminergic to glutamatergic interventions.
Marc Laruelle

Curr Opin Pharmacol· February 2014

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Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron emission tomography.
Robert A Comley, Cristian A Salinas, Mark Slifstein, Marcella Petrone, Carmine Marzano, Marc Laruelle

J Pharmacol Exp Ther· August 2013

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The second revision of the dopamine theory of schizophrenia: implications for treatment and drug development.
Marc Laruelle

Biol Psychiatry· July 2013

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The potent M1 receptor allosteric agonist GSK1034702 improves episodic memory in humans in the nicotine abstinence model of cognitive dysfunction.
Pradeep J Nathan, Jeannette Watson, Jesper Lund, Ceri H Davies, Gary Peters, Marc Laruelle

Int J Neuropsychopharmacol· May 2013

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Mathematical modelling of [¹¹C]-(+)-PHNO human competition studies.
Graham E Searle, John D Beaver, Andri Tziortzi, Robert A Comley, Massimo Bani, Marc Laruelle

Neuroimage· March 2013

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Imaging changes in synaptic acetylcholine availability in living human subjects.
Irina Esterlis, Jonas O Hannestad, Frederic Bois, R Andrew Sewell, Rachel F Tyndale, Marc Laruelle

J Nucl Med· January 2013

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Synthesis and characterization of two PET radioligands for the metabotropic glutamate 1 (mGlu1) receptor.
Yiyun Huang, Rajesh Narendran, Francois Bischoff, Ningning Guo, Sung A Bae, Marc Laruelle

Synapse· December 2012

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Biodistribution and radiation dosimetry of the serotonin 5-HT₆ ligand [¹¹C]GSK215083 determined from human whole-body PET.
Robert A Comley, Cristian Salinas, Romina Mizrahi, Irina Vitcu, Alvina Ng, Marc Laruelle

Mol Imaging Biol· August 2012

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Increased prefrontal cortical D₁ receptors in drug naive patients with schizophrenia: a PET study with [¹¹C]NNC112.
Anissa Abi-Dargham, Xiaoyan Xu, Judy L Thompson, Roberto Gil, Lawrence S Kegeles, Marc Laruelle

J Psychopharmacol· June 2012

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Affinity and selectivity of [¹¹C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo.
Jean-Dominique Gallezot, John D Beaver, Roger N Gunn, Nabeel Nabulsi, David Weinzimmer, Marc Laruelle

Synapse· June 2012

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Combining PET biodistribution and equilibrium dialysis assays to assess the free brain concentration and BBB transport of CNS drugs.
Roger N Gunn, Scott G Summerfield, Cristian A Salinas, Kevin D Read, Qi Guo, Marc Laruelle

J Cereb Blood Flow Metab· May 2012

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Sustained recreational use of ecstasy is associated with altered pre and postsynaptic markers of serotonin transmission in neocortical areas: a PET study with [¹¹C]DASB and [¹¹C]MDL 100907.
Nina Bl Urban, Ragy R Girgis, Peter S Talbot, Lawrence S Kegeles, X Xu, Marc Laruelle

Neuropsychopharmacology· May 2012

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Donepezil impairs memory in healthy older subjects: behavioural, EEG and simultaneous EEG/fMRI biomarkers.
Joshua H Balsters, Redmond G O'Connell, Mary P Martin, Alessandra Galli, Sarah M Cassidy, Marc Laruelle

PLoS One· March 2012

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Radiosynthesis and characterization of 11C-GSK215083 as a PET radioligand for the 5-HT6 receptor.
Christine A Parker, Roger N Gunn, Eugenii A Rabiner, Mark Slifstein, Robert Comley, Marc Laruelle

J Nucl Med· February 2012

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Extended characterisation of the serotonin 2A (5-HT2A) receptor-selective PET radiotracer 11C-MDL100907 in humans: quantitative analysis, test-retest reproducibility, and vulnerability to endogenous 5-HT tone.
Peter S Talbot, Mark Slifstein, Dah-Ren Hwang, Yiyun Huang, Erica Scher, Marc Laruelle

Neuroimage· January 2012

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Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humans.
Paul Shotbolt, Andri C Tziortzi, Graham E Searle, Alessandro Colasanti, Jasper van der Aart, Marc Laruelle

J Cereb Blood Flow Metab· January 2012

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Translational characterization of [11C]GSK931145, a PET ligand for the glycine transporter type 1.
Roger N Gunn, Venkatesha Murthy, Ana M Catafau, Graham Searle, Santiago Bullich, Marc Laruelle

Synapse· December 2011

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The 5-HT(2A) receptor and serotonin transporter in Asperger's disorder: A PET study with [¹¹C]MDL 100907 and [¹¹C]DASB.
Ragy R Girgis, Mark Slifstein, Xiaoyan Xu, W Gordon Frankle, Evdokia Anagnostou, Marc Laruelle

Psychiatry Res· December 2011

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Characterization of in vivo pharmacological properties and sensitivity to endogenous serotonin of [11C] P943: a positron emission tomography study in Papio anubis.
Khanum Ridler, Christophe Plisson, Eugenii A Rabiner, Roger N Gunn, Balu Easwaramoorthy, Marc Laruelle

Synapse· November 2011

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