Publications by authors named "Maria Ledesma"

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Sphingomyelin-induced glucocorticoid receptor alterations lead to impaired presynaptic plasticity in acid sphingomyelinase deficient neurons.
Sara Naya-Forcano, Ángel Gaudioso, Beatriz Soto-Huelin, Celia García-Vilela, César Venero, María Dolores Ledesma

Neurobiol Dis· September 2025

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Efficacy and safety of efavirenz in Niemann-Pick disease type C.
Jordi Gascón-Bayarri, Inmaculada Rico, Cristina Sánchez-Castañeda, María Dolores Ledesma, Thiago Carnaval

Neurotherapeutics· September 2025

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Secondary accumulation of lyso-platelet activating factors in lysosomal storage diseases.
Pamela Kell, Sonali Mishra, Heather L Gray-Edwards, Douglas R Martin, Angel Gaudioso, María Dolores Ledesma

Mol Genet Metab· August 2025

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Sex-dependent upregulation in oxylipins involved in inflammation resolution in the cerebellum of Niemann-Pick disease C1 mice.
Sandra M Camunas-Alberca, Maria Moran-Garrido, Ángel Gaudioso, Felipe da Costa Souza, Ana Gradillas, Maria Dolores Ledesma

Prog Neuropsychopharmacol Biol Psychiatry· June 2025

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Development of an Oxylipin Library Using Liquid Chromatography-Ion Mobility Quadrupole Time-of-Flight: Application to Mouse Brain Tissue.
Maria Moran-Garrido, Ameer Y Taha, Ángel Gaudioso, Maria Dolores Ledesma, Coral Barbas

Anal Chem· February 2025

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Enhanced mGluR intracellular activity causes psychiatric alterations in Niemann Pick type C disease.
Ana Toledano-Zaragoza, Violeta Enriquez-Zarralanga, Sara Naya-Forcano, Víctor Briz, Rocío Alfaro-Ruíz, María Dolores Ledesma

Cell Death Dis· October 2024

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Pilot-scale microalgae cultivation and wastewater treatment using high-rate ponds: a meta-analysis.
Sharon B Velásquez-Orta, Isaura Yáñez-Noguez, Ignacio Monje Ramírez, María Teresa Orta Ledesma

Environ Sci Pollut Res Int· July 2024

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Neurons regulate the esterification of bioactive lipid mediators in the brain of acid sphingomyelinase deficient mice.
Ameer Y Taha, Ángel Gaudioso, Maria Moran-Garrido, Sandra M Camunas-Alberca, Jaime Bachiller-Hernández, Maria Dolores Ledesma

Prog Neuropsychopharmacol Biol Psychiatry· February 2024

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Erratum to: Effect of Nordic Sensi® Chair on Behavioral and Psychological Symptoms of Dementia in Nursing Homes Residents: A Randomized Controlled Trial.
José María García-Alberca, María Dolores de la Rosa, Paloma Solo de Zaldívar, María Ledesma, Estela Oltra

J Alzheimers Dis· January 2024

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Effect of Nordic Sensi® Chair on Behavioral and Psychological Symptoms of Dementia in Nursing Homes Residents: A Randomized Controlled Trial.
José María García-Alberca, María Dolores de la Rosa, Paloma Solo de Zaldívar, María Ledesma, Estela Oltra

J Alzheimers Dis· December 2023

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"MiR-7 controls cholesterol biosynthesis through posttranscriptional regulation of DHCR24 expression".
Mario Fernández-de Frutos, Virginia Pardo-Marqués, Marta Torrecilla-Parra, Patricia Rada, Ana Pérez-García, María Dolores Ledesma

Biochim Biophys Acta Gene Regul Mech· June 2023

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Ellagic acid and its metabolites urolithins A/B ameliorate most common disease phenotypes in cellular and mouse models for lysosomal storage disorders by enhancing extracellular vesicle secretion.
Beatriz Soto-Huelin, Bohdan Babiy, Oscar Pastor, Mario Díaz-García, Ana Toledano-Zaragoza, María Dolores Ledesma

Neurobiol Dis· June 2023

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Modulation of Dietary Choline Uptake in a Mouse Model of Acid Sphingomyelinase Deficiency.
Ángel Gaudioso, Pilar Moreno-Huguet, Josefina Casas, Edward H Schuchman, María Dolores Ledesma

Int J Mol Sci· June 2023

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Sphingomyelin 16:0 is a therapeutic target for neuronal death in acid sphingomyelinase deficiency.
Ángel Gaudioso, Xuntian Jiang, Josefina Casas, Edward H Schuchman, María Dolores Ledesma

Cell Death Dis· April 2023

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Crimean-Congo Hemorrhagic Fever, Spain, 2013-2021.
Helena Miriam Lorenzo Juanes, Cristina Carbonell, Begoña Febrer Sendra, Amparo López-Bernus, Alberto Bahamonde, María Sánchez Ledesma

Emerg Infect Dis· February 2023

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Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males.
Liubov S Kalinichenko, Christiane Mühle, Tianye Jia, Felix Anderheiden, Maria Datz, Maria Dolores Ledesma

Cereb Cortex· January 2023

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Efficacy and safety clinical trial with efavirenz in patients diagnosed with adult Niemann-pick type C with cognitive impairment.
Jordi Gascón-Bayarri, Petru Cristian Simon, Roser Llop, Thiago Carnaval, María Dolores Ledesma

Medicine (Baltimore)· December 2022

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Models to study basic and applied aspects of lysosomal storage disorders.
Ángel Gaudioso, Teresa P Silva, María Dolores Ledesma

Adv Drug Deliv Rev· November 2022

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Heterologous booster response after inactivated virus BBIBP-CorV vaccination in older people.
Santiago Oviedo Rouco, Pamela E Rodriguez, Esteban A Miglietta, Pablo Rall, María M Gonzalez Lopez Ledesma

Lancet Infect Dis· August 2022

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Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects.
Liubov S Kalinichenko, Christiane Mühle, Tianye Jia, Felix Anderheiden, Maria Datz, Maria Dolores Ledesma

Mol Psychiatry· December 2021

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New paradigms for the treatment of lysosomal storage diseases: targeting the endocannabinoid system as a therapeutic strategy.
Edward H Schuchman, Maria D Ledesma, Calogera M Simonaro

Orphanet J Rare Dis· March 2021

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CERT reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease.
Simone M Crivelli, Qian Luo, Jo A A Stevens, Caterina Giovagnoni, Daan van Kruining, María Dolores Ledesma

Alzheimers Res Ther· February 2021

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Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signaling.
Adrián Bartoll, Ana Toledano-Zaragoza, Josefina Casas, Manuel Guzmán, Edward H Schuchman, María Dolores Ledesma

EMBO Mol Med· November 2020

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Apolipoprotein D-mediated preservation of lysosomal function promotes cell survival and delays motor impairment in Niemann-Pick type A disease.
Raquel Pascua-Maestro, Miriam Corraliza-Gomez, Cristian Fadrique-Rojo, Maria D Ledesma, Edward H Schuchman

Neurobiol Dis· October 2020

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Editorial: Lipids in the Brain.
Elisabetta Albi, Alice Vladimirovna Alessenko, Fanny M Elahi, Maria Dolores Ledesma

Front Neurol· July 2020

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