Publications by authors named "Mark D Chappell"

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Novel bicyclo[3.1.0]hexane analogs as antagonists of metabotropic glutamate 2/3 receptors for the treatment of depression.
Bruce A Dressman, Eric G Tromiczak, Mark D Chappell, Allie E Tripp, Steven J Quimby

Bioorg Med Chem Lett· December 2016

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Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371·HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepressant-Like Activity.
Mark D Chappell, Renhua Li, Stephon C Smith, Bruce A Dressman, Eric G Tromiczak

J Med Chem· December 2016

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Probing the SAR of dEpoB via chemical synthesis: a total synthesis evaluation of C26-(1,3-dioxolanyl)-12,13-desoxyepothilone B.
Mark D Chappell, Christina R Harris, Scott D Kuduk, Aaron Balog, Zhicai Wu

J Org Chem· November 2002

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Highly concise routes to epothilones: the total synthesis and evaluation of epothilone 490.
Kaustav Biswas, Hong Lin, Jon T Njardarson, Mark D Chappell, Ting-Chao Chou

J Am Chem Soc· August 2002

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