Publications by authors named "Zhicai Wu"

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Achieving 500-GHz communication over 1.2 km using an astronomical telescope with a quantum-limited superconducting receiver.
Wei Miao, Jing Li, Xianjin Deng, Jiaqiang Zhong, Yuan Ren, Feng Wu, Zhicai Wu

Natl Sci Rev· August 2025

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The gospel of sustainable development? Spatiotemporal evolution and configuration pathways of the coupling coordination of the digital economy, tourism development and eco-efficiency.
Zhicai Wu, Jialiang Xie

J Environ Manage· April 2025

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ResNet diagnosis of rotor faults in oil transfer pumps.
Lei Chen, Liang Dong, Zhi-Cai Wu, Chuan-Han Fan, Wei-Hua Shi

Heliyon· August 2024

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Lead Optimization to Advance Protease-Activated Receptor-1 Antagonists in Early Discovery.
Mihirbaran Mandal, Maria Madeira, Rupesh P Amin, Alexei V Buevich, Alan Cheng, Zhicai Wu

J Med Chem· April 2022

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Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors.
Chunhui Huang, Christian Fischer, Michelle R Machacek, Stephane Bogen, Tesfaye Biftu, Zhicai Wu

ACS Med Chem Lett· April 2022

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Soundscape Preference of Urban Residents in China in the Post-pandemic Era.
Jinxuan Liu, Jian Xu, Zhicai Wu, Yuru Cheng, Yuxin Gou

Front Psychol· December 2021

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Accelerating the discovery of DGAT1 inhibitors through the application of parallel medicinal chemistry (PMC).
Yang Yu, Zhicai Wu, Zhi-Cai Shi, Shuwen He, Zhong Lai

Bioorg Med Chem Lett· June 2019

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Benzimidazole-based DGAT1 inhibitors with a [3.1.0] bicyclohexane carboxylic acid moiety.
Shuwen He, Zhong Lai, Qingmei Hong, Jackie Shang, Mikhail Reibarkh, Zhicai Wu

Bioorg Med Chem Lett· May 2019

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Improvement of hERG-ROMK index of spirocyclic ROMK inhibitors through scaffold optimization and incorporation of novel pharmacophores.
Shuzhi Dong, Kelsey VanGelder, Zhi-Cai Shi, Yang Yu, Zhicai Wu

Bioorg Med Chem Lett· June 2017

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Microscale High-Throughput Experimentation as an Enabling Technology in Drug Discovery: Application in the Discovery of (Piperidinyl)pyridinyl-1H-benzimidazole Diacylglycerol Acyltransferase 1 Inhibitors.
Tim Cernak, Nathan J Gesmundo, Kevin Dykstra, Yang Yu, Zhicai Wu

J Med Chem· May 2017

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Discovery of MK-1832, a Kv1.5 inhibitor with improved selectivity and pharmacokinetics.
Scott E Wolkenberg, M Brad Nolt, Mark T Bilodeau, B Wesley Trotter, Peter J Manley, Zhicai Wu

Bioorg Med Chem Lett· February 2017

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Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists.
Zhong Lai, Shuwen He, Edward C Sherer, Zhicai Wu, Yang Yu

Bioorg Med Chem Lett· September 2015

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Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety.
Shuwen He, Qingmei Hong, Zhong Lai, David X Yang, Pauline C Ting, Zhicai Wu

ACS Med Chem Lett· October 2014

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Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists.
Derun Li, Zhicai Wu, Yang Yu, Richard G Ball, Liangqin Guo

ACS Med Chem Lett· June 2014

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Mineralocorticoid receptor antagonists: identification of heterocyclic amide replacements in the oxazolidinedione series.
Jason M Cox, Hong D Chu, Christine Yang, Hong C Shen, Zhicai Wu

Bioorg Med Chem Lett· April 2014

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Discovery of novel oxazolidinedione derivatives as potent and selective mineralocorticoid receptor antagonists.
Christine Yang, Hong C Shen, Zhicai Wu, Hong D Chu, Jason M Cox

Bioorg Med Chem Lett· August 2013

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Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid Moiety.
Shuwen He, Qingmei Hong, Zhong Lai, Zhicai Wu, Yang Yu

ACS Med Chem Lett· August 2013

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Discovery of a new class of potent prolylcarboxypeptidase inhibitors derived from alanine.
Zhicai Wu, Cangming Yang, Yusheng Xiong, Zhe Feng, Matthew Lombardo

Bioorg Med Chem Lett· February 2012

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Discovery of aminoheterocycles as potent and brain penetrant prolylcarboxypeptidase inhibitors.
Zhicai Wu, Cangming Yang, Thomas H Graham, Andreas Verras, Renee M Chabin

Bioorg Med Chem Lett· February 2012

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Imidazopyridine CB2 agonists: optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy.
B Wesley Trotter, Kausik K Nanda, Christopher S Burgey, Craig M Potteiger, James Z Deng, Zhicai Wu

Bioorg Med Chem Lett· April 2011

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Optimization of 2,3,5-trisubstituted pyridine derivatives as potent allosteric Akt1 and Akt2 inhibitors.
John C Hartnett, Stanley F Barnett, Mark T Bilodeau, Deborah Defeo-Jones, George D Hartman, Zhicai Wu

Bioorg Med Chem Lett· March 2008

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Rapid assembly of diverse and potent allosteric Akt inhibitors.
Zhicai Wu, Ronald G Robinson, Sheng Fu, Stanley F Barnett, Deborah Defeo-Jones

Bioorg Med Chem Lett· March 2008

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Development of pyridopyrimidines as potent Akt1/2 inhibitors.
Zhicai Wu, John C Hartnett, Lou Anne Neilson, Ronald G Robinson, Sheng Fu

Bioorg Med Chem Lett· February 2008

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Design and synthesis of 3,7-diarylimidazopyridines as inhibitors of the VEGF-receptor KDR.
Zhicai Wu, Mark E Fraley, Mark T Bilodeau, Mildred L Kaufman, Edward S Tasber

Bioorg Med Chem Lett· February 2004

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Probing the SAR of dEpoB via chemical synthesis: a total synthesis evaluation of C26-(1,3-dioxolanyl)-12,13-desoxyepothilone B.
Mark D Chappell, Christina R Harris, Scott D Kuduk, Aaron Balog, Zhicai Wu

J Org Chem· November 2002

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