Publications by authors named "Mark Fereshteh"

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μMap-FFPE: A High-Resolution Protein Proximity Labeling Platform for Formalin-Fixed Paraffin-Embedded Tissue Samples.
Noah B Bissonnette, Marie E Zamanis, Steve D Knutson, Zane Boyer, Angelo Harris, Mark Fereshteh

J Am Chem Soc· July 2025

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DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.
Alexander Muik, Homer C Adams 3rd, Friederike Gieseke, Isil Altintas, Kristina B Schoedel, Mark Fereshteh

J Immunother Cancer· June 2022

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Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors.
Alexander Muik, Elena Garralda, Isil Altintas, Friederike Gieseke, Ravit Geva, Mark Fereshteh

Cancer Discov· May 2022

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Discovery of Non-Nucleotide Small-Molecule STING Agonists Chemotype Hybridization.
Emily C Cherney, Liping Zhang, Julian Lo, Tram Huynh, Donna Wei, Mark Fereshteh

J Med Chem· February 2022

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Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors.
Emily C Cherney, Liping Zhang, Weiwei Guo, Audris Huang, David Williams, Mark Fereshteh

ACS Med Chem Lett· July 2021

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Discovery of Imidazopyridines as Potent Inhibitors of Indoleamine 2,3-Dioxygenase 1 for Cancer Immunotherapy.
Liping Zhang, Emily C Cherney, Xiao Zhu, Tai-An Lin, Johnni Gullo-Brown, Mark Fereshteh

ACS Med Chem Lett· March 2021

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Discovery and Preclinical Evaluation of BMS-986242, a Potent, Selective Inhibitor of Indoleamine-2,3-dioxygenase 1.
Emily C Cherney, Liping Zhang, Susheel Nara, Xiao Zhu, Johnni Gullo-Brown, Mark Fereshteh

ACS Med Chem Lett· February 2021

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Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.
Satheesh Nair, Sreekantha Ratna Kumar, Venkatram Reddy Paidi, Ramesh Sistla, Durgarao Kantheti, Mark P Fereshteh

ACS Med Chem Lett· July 2020

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Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGFβR1 Inhibitor as an Immuno-oncology Agent.
Upender Velaparthi, Chetan Padmakar Darne, Jayakumar Warrier, Peiying Liu, Hasibur Rahaman, Mark P Fereshteh

ACS Med Chem Lett· February 2020

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Critical role of kinase activity of hematopoietic progenitor kinase 1 in anti-tumor immune surveillance.
Jinqi Liu, Joshua Curtin, Dan You, Stephen Hillerman, Bifang Li-Wang, Mark Fereshteh

PLoS One· November 2019

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Discovery of 4-Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents.
Yong Zhang, Yufen Zhao, Andrew J Tebben, Steven Sheriff, Max Ruzanov, Mark P Fereshteh

ACS Med Chem Lett· November 2018

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Miniaturized High-Throughput Multiparameter Flow Cytometry Assays Measuring In Vitro Human Dendritic Cell Maturation and T-Cell Activation in Mixed Lymphocyte Reactions.
Yi Fan, Joseph G Naglich, Jennifer D Koenitzer, Humberto Ribeiro, Jonathan Lippy, Mark P Fereshteh

SLAS Discov· August 2018

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Heterobicyclic inhibitors of transforming growth factor beta receptor I (TGFβRI).
Lalgudi S Harikrishnan, Jayakumar Warrier, Andrew J Tebben, Gopikishan Tonukunuru, Sudhakara R Madduri, Mark Fereshteh

Bioorg Med Chem· March 2018

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Development of a Human Whole Blood Screening Platform to Monitor JAK/STAT Signaling Using High-Throughput Flow Cytometry.
Mark P Fereshteh, Xin Li, Sha Li, Yi Fan, Rosemary Zhang

J Biomol Screen· September 2016

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Antroquinonol A: Scalable Synthesis and Preclinical Biology of a Phase 2 Drug Candidate.
Matthew T Villaume, Eran Sella, Garrett Saul, Robert M Borzilleri, Joseph Fargnoli, Mark P Fereshteh

ACS Cent Sci· January 2016

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Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth.
Jonathan W Kotula, Jinpeng Sun, Margie Li, Elizabeth D Pratico, Mark P Fereshteh

PLoS One· January 2015

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β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
Mark Fereshteh, Takahiro Ito, Jeffrey J Kovacs, Chen Zhao, Hyog Young Kwon

Proc Natl Acad Sci U S A· July 2012

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Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth.
James Kim, Jean Y Tang, Ruoyu Gong, Jynho Kim, John J Lee, Mark Fereshteh

Cancer Cell· April 2010

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Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia.
Chen Zhao, Alan Chen, Catriona H Jamieson, Mark Fereshteh, Annelie Abrahamsson

Nature· April 2009

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Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells.
Annabell S Oh, John T Lahusen, Christopher D Chien, Mark P Fereshteh, Xiaolong Zhang

Mol Cell Biol· November 2008

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The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice.
Mark P Fereshteh, Maddalena T Tilli, Sung Eun Kim, Jianming Xu, Bert W O'Malley

Cancer Res· May 2008

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Epidermal growth factor receptor tyrosine phosphorylation and signaling controlled by a nuclear receptor coactivator, amplified in breast cancer 1.
Tyler Lahusen, Mark Fereshteh, Annabell Oh, Anton Wellstein, Anna T Riegel

Cancer Res· August 2007

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