Publications by authors named "Mark Searle"

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An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins.
Andrew Brennan, Robert Layfield, Jed Long, Huw E L Williams, Neil J Oldham, Mark S Searle

J Biol Chem· February 2022

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Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery.
Bubacarr G Kaira, Alexandre Slater, Keith R McCrae, Ingrid Dreveny, Ummay Sumya, Mark Searle

Blood· October 2020

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The indirect influence of child play on the association between parent perceptions of the neighborhood environment and sense of community.
Allison Ross, Lisa Wood, Mark Searle

Health Place· September 2020

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G-quadruplex ligands mediate downregulation of DUX4 expression.
Lukasz Ciszewski, Ngoc Lu-Nguyen, Alex Slater, Andrew Brennan, Huw E L Williams, Mark S Searle

Nucleic Acids Res· May 2020

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The association between leisure time physical activity and happiness: Testing the indirect role of health perception.
Allison Ross, Scott Cloutier, Mark Searle

J Community Psychol· June 2019

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Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib.
Juliet Morgan, Muhammad Saleem, Ruiqi Ng, Caroline Armstrong, Szu S Wong, Mark S Searle

Blood Adv· May 2019

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DNA replication initiation in Bacillus subtilis: structural and functional characterization of the essential DnaA-DnaD interaction.
Eleyna Martin, Huw E L Williams, Matthaios Pitoulias, Daniel Stevens, Charles Winterhalter, Mark S Searle

Nucleic Acids Res· February 2019

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Active Transportation: The Role of Parent Attitude, The Physical Environment, and Social Capital.
Allison Ross, Ja Youn Kwon, Pamela Hodges Kulinna, Mark Searle

J Phys Act Health· December 2018

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Method for the Purification of Endogenous Unanchored Polyubiquitin Chains.
Daniel Scott, Jo Strachan, Varun Gopala Krishna, Barry Shaw, David J Tooth, Mark S Searle

Methods Mol Biol· January 2018

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ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling.
Alice Goode, Sarah Rea, Melanie Sultana, Barry Shaw, Mark S Searle

Mol Cell Neurosci· October 2016

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SilE is an intrinsically disordered periplasmic "molecular sponge" involved in bacterial silver resistance.
Karishma R Asiani, Huw Williams, Louise Bird, Matthew Jenner, Mark S Searle

Mol Microbiol· September 2016

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A Fluorescence Resonance Energy Transfer Assay For Monitoring α- Synclein Aggregation in a Caenorhabditis Elegans Model For Parkinson's Disease.
Archana Nagarajan, Rakesh Bodhicharla, Jody Winter, Charumathi Anbalagan, Kevin Morgan, Mark Searle

CNS Neurol Disord Drug Targets· July 2016

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Mass spectrometry insights into a tandem ubiquitin-binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin.
Daniel Scott, Tom P Garner, Jed Long, Jo Strachan, Sharad C Mistry, Mark S Searle

Proteomics· July 2016

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Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD.
Alice Goode, Kevin Butler, Jed Long, James Cavey, Daniel Scott, Mark S Searle

Autophagy· July 2016

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Enantiopure titanocene complexes--direct evidence for paraptosis in cancer cells.
Melchior Cini, Huw Williams, Mike W Fay, Mark S Searle, Simon Woodward

Metallomics· March 2016

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Correction: Enantiopure titanocene complexes--direct evidence for paraptosis in cancer cells.
Melchior Cini, Huw Williams, Mike W Fay, Mark S Searle, Simon Woodward

Metallomics· February 2016

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The role of short RNA loops in recognition of a single-hairpin exon derived from a mammalian-wide interspersed repeat.
Jana Kralovicova, Alpa Patel, Mark Searle, Igor Vorechovsky

RNA Biol· November 2015

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Ubiquitin-binding domains: mechanisms of ubiquitin recognition and use as tools to investigate ubiquitin-modified proteomes.
Daniel Scott, Neil J Oldham, Jo Strachan, Mark S Searle, Robert Layfield

Proteomics· March 2015

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Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences.
Alex R O Cousins, Dougal Ritson, Pallavi Sharma, Malcolm F G Stevens, John E Moses, Mark S Searle

Chem Commun (Camb)· December 2014

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A targeted oligonucleotide enhancer of SMN2 exon 7 splicing forms competing quadruplex and protein complexes in functional conditions.
Lindsay D Smith, Rachel L Dickinson, Christian M Lucas, Alex Cousins, Alexey A Malygin, Mark S Searle

Cell Rep· October 2014

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SQSTM1 mutations--bridging Paget disease of bone and ALS/FTLD.
Sarah L Rea, Veronika Majcher, Mark S Searle, Rob Layfield

Exp Cell Res· July 2014

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Paget disease of bone-associated UBA domain mutations of SQSTM1 exert distinct effects on protein structure and function.
Alice Goode, Jed E Long, Barry Shaw, Stuart H Ralston, Micaela Rios Visconti, Mark S Searle

Biochim Biophys Acta· July 2014

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Optimal antisense target reducing INS intron 1 retention is adjacent to a parallel G quadruplex.
Jana Kralovicova, Ana Lages, Alpa Patel, Ashish Dhir, Emanuele Buratti, Mark Searle

Nucleic Acids Res· July 2014

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A sequence-based approach for prediction of CsrA/RsmA targets in bacteria with experimental validation in Pseudomonas aeruginosa.
Prajna R Kulkarni, Tao Jia, Sarah A Kuehne, Thomas M Kerkering, Elizabeth R Morris, Mark S Searle

Nucleic Acids Res· June 2014

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Enthalpy/entropy compensation effects from cavity desolvation underpin broad ligand binding selectivity for rat odorant binding protein 3.
Katherine L Portman, Jed Long, Stephen Carr, Loïc Briand, Donald J Winzor, Mark S Searle

Biochemistry· April 2014

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