Publications by authors named "Mark Sinnamon"

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PKM2 is not required for colon cancer initiated by APC loss.
Allison N Lau, William J Israelsen, Jatin Roper, Mark J Sinnamon, Larissa Georgeon

Cancer Metab· November 2017

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Review of MRI wrist examination since introduction of Medicare item number.
Brendan J Jones, Mark Sinnamon

J Med Imaging Radiat Oncol· June 2015

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Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Peter J Belmont, Ping Jiang, Trevor D McKee, Tao Xie, Jason Isaacson, Mark J Sinnamon

Sci Signal· November 2014

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Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer.
Jatin Roper, Mark J Sinnamon, Erin M Coffee, Peter Belmont, Lily Keung

Cancer Lett· June 2014

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Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease.
Peter J Belmont, Eva Budinska, Ping Jiang, Mark J Sinnamon, Erin Coffee

Dis Model Mech· June 2014

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In vivo optical molecular imaging of matrix metalloproteinase activity following celecoxib therapy for colorectal cancer.
Rahul A Sheth, Alexandra Kunin, Lars Stangenberg, Mark Sinnamon, Kenneth E Hung

Mol Imaging· September 2013

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Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation.
Eric S Martin, Peter J Belmont, Mark J Sinnamon, Larissa Georgeon Richard, Jing Yuan

Clin Cancer Res· June 2013

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Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer.
Erin M Coffee, Anthony C Faber, Jatin Roper, Mark J Sinnamon, Gautam Goel

Clin Cancer Res· May 2013

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The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer.
Jatin Roper, Michael P Richardson, Wei Vivian Wang, Larissa Georgeon Richard, Wei Chen, Mark J Sinnamon

PLoS One· February 2012

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Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation.
Jie Zhang, Jiusong Sun, Jes S Lindholt, Galina K Sukhova, Mark Sinnamon

Circ Res· May 2011

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Essential role for mast cell tryptase in acute experimental colitis.
Matthew J Hamilton, Mark J Sinnamon, Gregory D Lyng, Jonathan N Glickman, Xueli Wang

Proc Natl Acad Sci U S A· January 2011

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Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse.
Mark J Sinnamon, Kathy J Carter, Barbara Fingleton, Lynn M Matrisian

Int J Exp Pathol· December 2008

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A protective role of mast cells in intestinal tumorigenesis.
Mark J Sinnamon, Kathy J Carter, Lauren P Sims, Bonnie Lafleur, Barbara Fingleton

Carcinogenesis· April 2008

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Hu/Mu ProtIn oligonucleotide microarray: dual-species array for profiling protease and protease inhibitor gene expression in tumors and their microenvironment.
Donald R Schwartz, Kamiar Moin, Bin Yao, Lynn M Matrisian, Lisa M Coussens, Mark Sinnamon

Mol Cancer Res· May 2007

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Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer.
Heath B Acuff, Mark Sinnamon, Barbara Fingleton, Braden Boone, Shawn E Levy

Cancer Res· August 2006

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