Publications by authors named "Martin Mense"

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Author Correction: A streamlined base editor engineering strategy to reduce bystander editing.
Izabella Valdez, Ian O'Connor, Divesh Patel, Katherine Gierer, Jan Harrington, Martin Mense

Nat Commun· November 2025

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A streamlined base editor engineering strategy to reduce bystander editing.
Izabella Valdez, Ian O'Connor, Divesh Patel, Katherine Gierer, Jan Harrington, Martin Mense

Nat Commun· August 2025

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ACE-tRNAs are a platform technology for suppressing nonsense mutations that cause cystic fibrosis.
Wooree Ko, Joseph J Porter, Sacha Spelier, Emily G Sorensen, Priyanka Bhatt, Martin Mense

Nucleic Acids Res· July 2025

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In vitro modulator responsiveness of 655 CFTR variants found in people with cystic fibrosis.
Hermann Bihler, Andrey Sivachenko, Linda Millen, Priyanka Bhatt, Amita Thakerar Patel, Martin Mense

J Cyst Fibros· July 2024

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CFTR mRNAs with nonsense codons are degraded by the SMG6-mediated endonucleolytic decay pathway.
Edward J Sanderlin, Melissa M Keenan, Martin Mense, Alexey S Revenko, Brett P Monia

Nat Commun· April 2022

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A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion.
Jyoti Sharma, Ming Du, Eric Wong, Venkateshwar Mutyam, Yao Li, Martin Mense

Nat Commun· July 2021

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Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition.
Gianni Carraro, Justin Langerman, Shan Sabri, Zareeb Lorenzana, Arunima Purkayastha, Martin Mense

Nat Med· May 2021

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Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope.
Tingting Jiang, Jordana M Henderson, Kevin Coote, Yi Cheng, Hillary C Valley, Martin Mense

Nat Commun· April 2020

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Exploring the basic mechanisms in Cystic Fibrosis: Promoting data presentation and discussion at the 16th ECFS Basic Science Conference.
Isabelle Callebaut, Martin Mense, Carlos M Farinha

J Cyst Fibros· March 2020

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Nonsense-mediated RNA Decay Pathway Inhibition Restores Expression and Function of W1282X CFTR.
Melissa M Keenan, Lulu Huang, Nikole J Jordan, Eric Wong, Yi Cheng, Martin Mense

Am J Respir Cell Mol Biol· September 2019

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Isogenic cell models of cystic fibrosis-causing variants in natively expressing pulmonary epithelial cells.
Hillary C Valley, Katherine M Bukis, Alisa Bell, Yi Cheng, Eric Wong, Martin Mense

J Cyst Fibros· July 2019

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CFTR modulator theratyping: Current status, gaps and future directions.
John Paul Clancy, Calvin U Cotton, Scott H Donaldson, George M Solomon, Donald R VanDevanter, Martin Mense

J Cyst Fibros· January 2019

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A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.
Daniel T Montoro, Adam L Haber, Moshe Biton, Vladimir Vinarsky, Brian Lin, Martin Mense

Nature· August 2018

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Partial rescue of F508del-cystic fibrosis transmembrane conductance regulator channel gating with modest improvement of protein processing, but not stability, by a dual-acting small molecule.
Jia Liu, Hermann Bihler, Carlos M Farinha, Nikhil T Awatade, Ana M Romão, Martin Mense

Br J Pharmacol· April 2018

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High-Throughput Screening for Readthrough Modulators of CFTR PTC Mutations.
Feng Liang, Haibo Shang, Nikole J Jordan, Eric Wong, Dayna Mercadante, Martin Mense

SLAS Technol· June 2017

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Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations.
Venkateshwar Mutyam, Ming Du, Xiaojiao Xue, Kim M Keeling, E Lucile White, Martin Mense

Am J Respir Crit Care Med· November 2016

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Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells.
Hongmei Mou, Vladimir Vinarsky, Purushothama Rao Tata, Karissa Brazauskas, Soon H Choi, Martin Mense

Cell Stem Cell· August 2016

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A novel approach to recovery of function of mutant proteins by slowing down translation.
Anatoli B Meriin, Martin Mense, Jeff D Colbert, Feng Liang, Hermann Bihler

J Biol Chem· October 2012

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Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator.
Rhea P Hudson, P Andrew Chong, Irina I Protasevich, Robert Vernon, Efrat Noy, Martin Mense

J Biol Chem· August 2012

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Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening.
Ori Kalid, Martin Mense, Sharon Fischman, Alina Shitrit, Hermann Bihler

J Comput Aided Mol Des· December 2010

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In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer.
Martin Mense, Paola Vergani, Dennis M White, Gal Altberg, Angus C Nairn

EMBO J· October 2006

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Extracellular domains, transmembrane segments, and intracellular domains interact to determine the cation selectivity of Na,K- and gastric H,K-ATPase.
Martin Mense, Vanathy Rajendran, Rhoda Blostein, Michael J Caplan

Biochemistry· August 2002

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