Publications by authors named "Martin Scanlon"

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Discovery of a Cryptic Pocket in EcDsbA Opens New Opportunities for Antibacterial Discovery.
Biswaranjan Mohanty, Wesam S Alwan, Menachem J Gunzburg, Olga Ilyichova, Martin L Williams, Martin J Scanlon

Angew Chem Int Ed Engl· December 2025

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NMR and SPR Fragment-Based Screening Can Produce Novel High Affinity Small Molecule Hits against Structured RNAs.
Brooke X C Kwai, Indu R Chandrashekaran, Biswaranjan Mohanty, Menachem J Gunzburg, Bradley C Doak, Martin J Scanlon

ACS Chem Biol· December 2025

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Exploring the Ligandability of 53BP1 through Fragment-Based Approaches.
Beatrice Chiew, Menachem J Gunzburg, Caroline A Foley, Hong Zeng, Aiping Dong, Martin J Scanlon

ACS Med Chem Lett· July 2025

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Methods to accelerate PROTAC drug discovery.
Jeyan Osman, Philip E Thompson, Manuela Jörg, Martin J Scanlon

Biochem J· June 2025

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Extrusion of Oilseed-Based Ingredients: Unlocking New Potential for Sustainable Protein Solutions.
Aayushi Kadam, Martin G Scanlon, Filiz Koksel

Compr Rev Food Sci Food Saf· May 2025

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Evaluation of the Anti-Inflammatory Effects of Novel Fatty Acid-Binding Protein 4 Inhibitors in Microglia.
Yi Ling Low, Ethan Kreutzer, Indu R Chandrashekaran, Luke A Adams, Jason Pun, Martin J Scanlon

J Neuroimmune Pharmacol· April 2025

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Identification of an Allene Warhead That Selectively Targets a Histidine Residue in the Oxidoreductase Enzyme DsbA.
Yildiz Tasdan, Gautham R Balaji, Naureen Akhtar, Olga Ilyichova, Taylor Cunliffe, Martin J Scanlon

ACS Med Chem Lett· April 2025

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Fluoromethylketone-Fragment Conjugates Designed as Covalent Modifiers of EcDsbA are Atypical Substrates.
Bradley C Doak, Rebecca L Whitehouse, Kieran Rimmer, Martin Williams, Begoña Heras, Martin J Scanlon

ChemMedChem· August 2024

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Multiplexed Native Mass Spectrometry Determination of Ligand Selectivity for Fatty Acid-Binding Proteins.
Michelle Q Phan, Indu R Chandrashekaran, Naureen Akhtar, Evgenia Konstantinidou, Shane M Devine, Martin J Scanlon

ACS Med Chem Lett· July 2024

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Canola Seed Protein: Pretreatment, Extraction, Structure, Physicochemical and Functional Characteristics.
Huipeng Zhu, Lu Wang, Xiaoyu Li, John Shi, Martin Scanlon

Foods· April 2024

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Microemulsion: a novel alternative technique for edible oil extraction_a mechanistic viewpoint.
Soleiman Abbasi, Martin G Scanlon

Crit Rev Food Sci Nutr· November 2023

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Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra-Terminal Domain.
Luke A Adams, Lorna E Wilkinson-White, Menachem J Gunzburg, Stephen J Headey, Biswaranjan Mohanty, Martin J Scanlon

J Med Chem· April 2023

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Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rebecca L Whitehouse, Wesam S Alwan, Olga V Ilyichova, Ashley J Taylor, Indu R Chandrashekaran, Martin J Scanlon

RSC Med Chem· January 2023

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Relationship between nitrogen functionality and wheat flour dough rheology: Extensional and shear approaches.
Susane Trevisan, Ali Salimi Khorshidi, Martin G Scanlon

Food Res Int· December 2022

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Improved Extraction Efficiency and Antioxidant Activity of Defatted Canola Meal Extract Phenolic Compounds Obtained from Air-Fried Seeds.
Olamide S Fadairo, Ruchira Nandasiri, Thu Nguyen, N A Michael Eskin, Rotimi E Aluko, Martin G Scanlon

Antioxidants (Basel)· December 2022

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Novel small molecules that increase the susceptibility of Neisseria gonorrhoeae to cationic antimicrobial peptides by inhibiting lipid A phosphoethanolamine transferase.
Christopher Mullally, Keith A Stubbs, Van C Thai, Anandhi Anandan, Stephanie Bartley, Martin J Scanlon

J Antimicrob Chemother· August 2022

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Methyl probes in proteins for determining ligand binding mode in weak protein-ligand complexes.
Biswaranjan Mohanty, Julien Orts, Geqing Wang, Stefan Nebl, Wesam S Alwan, Martin J Scanlon

Sci Rep· July 2022

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Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials.
Geqing Wang, Biswaranjan Mohanty, Martin L Williams, Bradley C Doak, Rabeb Dhouib, Martin J Scanlon

ChemMedChem· March 2022

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Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA.
Guillaume A Petit, Biswaranjan Mohanty, Róisín M McMahon, Stefan Nebl, David H Hilko, Martin J Scanlon

Acta Crystallogr D Struct Biol· January 2022

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Binding of a pyrimidine RNA base-mimic to SARS-CoV-2 nonstructural protein 9.
Dene R Littler, Biswaranjan Mohanty, Shea A Lowery, Rhys N Colson, Benjamin S Gully, Martin J Scanlon

J Biol Chem· September 2021

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Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.
Luke F Duncan, Geqing Wang, Olga V Ilyichova, Rabeb Dhouib, Makrina Totsika, Martin J Scanlon

Bioorg Med Chem· September 2021

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Association of asparagine concentration in wheat with cultivar, location, fertilizer, and their interaction.
Lovemore Nkhata Malunga, Nancy Ames, Ali Salimi Khorshidi, Sijo Joseph Thandapilly, Weikai Yan, Martin G Scanlon

Food Chem· May 2021

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NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide-dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei.
Stefan Nebl, Wesam S Alwan, Martin L Williams, Gaurav Sharma, Ashley Taylor, Martin J Scanlon

J Biomol NMR· November 2020

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Characterization of the ergometric properties of commercial bioactive dairy peptides.
Luis E Maya, Martin G Scanlon

Curr Res Food Sci· November 2020

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Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiL).
Matthew R Bentley, Olga V Ilyichova, Geqing Wang, Martin L Williams, Gaurav Sharma, Martin J Scanlon

J Med Chem· July 2020

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