Publications by authors named "Martin Traebert"

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Toxicology and safety pharmacology investigations on the nervous system: 2024 industry survey.
Simon Authier, Marcus S Delatte, Alison Wakeford, Wendy Halpern, Owen McMaster, Martin Traebert

J Pharmacol Toxicol Methods· September 2025

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Taking a deep breath: Evidence-based approaches to respiratory safety assessment.
John J Kremer, Matt Bridgland-Taylor, Matt Clark, Mike G Rolf, Martin Traebert

J Pharmacol Toxicol Methods· June 2025

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Electrophysiological Changes in the Rabbit Ventricular Wedge and Human-Induced Pluripotent Stem-Cell Derived (IPSC) Cardiomyocytes Translate to Severe Arrhythmia Observed in a Canine Toxicology Study, Not Predicted by Standard In Vitro Ion Channel Assays.
Alan P Brown, Gregory S Friedrichs, Hai-Ming Tang, Martin Traebert, Valerie Weber

Int J Toxicol· May 2024

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Comparative study for the IMI2-NeuroDeRisk project on microelectrode arrays to derisk drug-induced seizure liability.
Jin Zhai, Martin Traebert, Kurt Zimmermann, Annie Delaunois, Leandro Royer

J Pharmacol Toxicol Methods· February 2024

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GABA receptor-mediated seizure liabilities: a mixed-methods screening approach.
Konstantina Bampali, Filip Koniuszewski, Florian D Vogel, Jure Fabjan, Christos Andronis, Martin Traebert

Cell Biol Toxicol· December 2023

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Optimization of a Class of Dihydrobenzofurane Analogs toward Orally Efficacious YAP-TEAD Protein-Protein Interaction Inhibitors.
Holger Sellner, Emilie Chapeau, Pascal Furet, Markus Voegtle, Bahaa Salem, Martin Traebert

ChemMedChem· June 2023

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Cardiotoxic Potential of Hydroxychloroquine, Chloroquine and Azithromycin in Adult Human Primary Cardiomyocytes.
Pierre Jordaan, Bérengère Dumotier, Martin Traebert, Paul E Miller, Andre Ghetti

Toxicol Sci· April 2021

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Nonclinical species sensitivity to convulsions: An IQ DruSafe consortium working group initiative.
Jamie K DaSilva, Laura Breidenbach, Tracy Deats, Dingzhou Li, Kimberley Treinen, Martin Traebert

J Pharmacol Toxicol Methods· February 2021

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Time for a Fully Integrated Nonclinical-Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective.
Hugo M Vargas, Michael G Rolf, Todd A Wisialowski, William Achanzar, Anthony Bahinski, Martin Traebert

Clin Pharmacol Ther· February 2021

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Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.
Gary Gintant, Emily Pfeiffer Kaushik, Tromondae Feaster, Sonja Stoelzle-Feix, Yasunari Kanda, Martin Traebert

Regul Toxicol Pharmacol· November 2020

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Is there a role for the no observed adverse effect level in safety pharmacology?
Tomas Mow, Ninette K Andersen, Nils Dragsted, Anders B Lassen, Morten Laursen, Martin Traebert

J Pharmacol Toxicol Methods· September 2020

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Reprint of: Nonclinical species sensitivity to convulsions: An IQ DruSafe consortium working group initiative.
Jamie K DaSilva, Laura Breidenbach, Tracy Deats, Dingzhou Li, Kimberly Treinen, Martin Traebert

J Pharmacol Toxicol Methods· September 2020

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Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.
Colin K Skepper, Duncan Armstrong, Carl J Balibar, Daniel Bauer, Cornelia Bellamacina, Martin Traebert

J Med Chem· July 2020

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The roles of human induced pluripotent stem cell-derived cardiomyocytes in drug discovery: managing in vitro safety study expectations.
Gary Gintant, Martin Traebert

Expert Opin Drug Discov· June 2020

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Neurofunctional test batteries in safety pharmacology - Current and emerging considerations for the drug development process.
Samuel J Jackson, Simon Authier, Henning Brohmann, Susan M G Goody, David Jones, Martin Traebert

J Pharmacol Toxicol Methods· March 2020

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Cross - site comparison of excitation-contraction coupling using impedance and field potential recordings in hiPSC cardiomyocytes.
Corina T Bot, Krisztina Juhasz, Fabian Haeusermann, Liudmila Polonchuk, Martin Traebert

J Pharmacol Toxicol Methods· January 2019

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The Safety Pharmacology Society salary survey.
Michael K Pugsley, Simon Authier, Tiffini Brabham, Maxim Soloviev, Carrie G Markgraf, Martin Traebert

J Pharmacol Toxicol Methods· November 2017

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Blinded Contractility Analysis in hiPSC-Cardiomyocytes in Engineered Heart Tissue Format: Comparison With Human Atrial Trabeculae.
Ingra Mannhardt, Alexandra Eder, Berengere Dumotier, Maksymilian Prondzynski, Elisabeth Krämer, Martin Traebert

Toxicol Sci· July 2017

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Human ex-vivo action potential model for pro-arrhythmia risk assessment.
Guy Page, Phachareeya Ratchada, Yannick Miron, Guido Steiner, Andre Ghetti, Martin Traebert

J Pharmacol Toxicol Methods· May 2017

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Assessing the predictive value of the rodent neurofunctional assessment for commonly reported adverse events in phase I clinical trials.
Andy N Mead, Hamid R Amouzadeh, Kathryn Chapman, Lorna Ewart, Alessandra Giarola, Martin Traebert

Regul Toxicol Pharmacol· October 2016

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Histone Deacetylase Inhibitors Prolong Cardiac Repolarization through Transcriptional Mechanisms.
Stan Spence, Mark Deurinck, Haisong Ju, Martin Traebert, LeeAnne McLean

Toxicol Sci· September 2016

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Differentiating electrophysiological effects and cardiac safety of drugs based on the electrocardiogram: a blinded validation.
Tengxian Liu, Martin Traebert, Haisong Ju, Willi Suter, Donglin Guo

Heart Rhythm· October 2012

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A potent and selective S1P(1) antagonist with efficacy in experimental autoimmune encephalomyelitis.
Jean Quancard, Birgit Bollbuck, Philipp Janser, Daniela Angst, Frédéric Berst, Martin Traebert

Chem Biol· September 2012

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Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.
Michael D Shultz, Xueying Cao, Christine H Chen, Young Shin Cho, Nicole R Davis, Martin Traebert

J Med Chem· July 2011

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