Publications by authors named "Mary Gates"

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ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER breast cancer.
Jackson Liang, Xiaosai Yao, Patrick Aouad, Bu-Er Wang, Lisa Crocker, Mary R Gates

Nat Cancer· February 2025

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Mass Balance, Metabolic Pathways, Absolute Bioavailability, and Pharmacokinetics of Giredestrant in Healthy Subjects.
Smita Kshirsagar, Ya-Chi Chen, Jiajie Yu, Mary R Gates, Sonoko Kawakatsu

Drug Metab Dispos· July 2024

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Phase Ia/b Study of Giredestrant ± Palbociclib and ± Luteinizing Hormone-Releasing Hormone Agonists in Estrogen Receptor-Positive, HER2-Negative, Locally Advanced/Metastatic Breast Cancer.
Komal L Jhaveri, Meritxell Bellet, Nicholas C Turner, Sherene Loi, Aditya Bardia, Mary R Gates

Clin Cancer Res· February 2024

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Optimizing Early-stage Clinical Pharmacology Evaluation to Accelerate Clinical Development of Giredestrant in Advanced Breast Cancer.
Vikram Malhi, Priya Agarwal, Mary R Gates, Lichuan Liu, Jianshuang Wang

Cancer Res Commun· December 2023

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An Open-label Phase I Study of GDC-0927 in Postmenopausal Women with Locally Advanced or Metastatic Estrogen Receptor-Positive Breast Cancer.
Sarat Chandarlapaty, Maura N Dickler, Jose Alejandro Perez Fidalgo, Rafael Villanueva-Vázquez, Jennifer Giltnane, Mary Gates

Clin Cancer Res· August 2023

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The oral selective estrogen receptor degrader GDC-0810 (ARN-810) in postmenopausal women with hormone receptor-positive HER2-negative (HR + /HER2 -) advanced/metastatic breast cancer.
Aditya Bardia, Ingrid Mayer, Eric Winer, Hannah M Linden, Cynthia X Ma, Mary Gates

Breast Cancer Res Treat· January 2023

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Giredestrant reverses progesterone hypersensitivity driven by estrogen receptor mutations in breast cancer.
Jackson Liang, Ellen Rei Ingalla, Xiaosai Yao, Bu-Er Wang, Lisa Tai, Mary R Gates

Sci Transl Med· September 2022

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Phase Ib study of the MEK inhibitor cobimetinib (GDC-0973) in combination with the PI3K inhibitor pictilisib (GDC-0941) in patients with advanced solid tumors.
Geoffrey I Shapiro, Patricia LoRusso, Eunice Kwak, Susan Pandya, Charles M Rudin, Mary R Gates

Invest New Drugs· April 2020

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Effect of OATP1B1/1B3 Inhibitor GDC-0810 on the Pharmacokinetics of Pravastatin and Coproporphyrin I/III in Healthy Female Subjects.
Lichuan Liu, Sravanthi Cheeti, Kenta Yoshida, Edna Choo, Eugene Chen, Mary Gates

J Clin Pharmacol· November 2018

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Application of a Novel 'Make and Test in Parallel' Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects.
Sravanthi Cheeti, Hao Helen Hou, Eric Nelson, Helen Walker, Buyun Chen, Mary Gates

Pharm Res· October 2018

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Correction to: Application of a Novel 'Make and Test in Parallel' Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects.
Sravanthi Cheeti, Hao Helen Hou, Eric Nelson, Helen Walker, Buyun Chen, Mary Gates

Pharm Res· October 2018

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Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans.
Ryan H Takahashi, Edna F Choo, Shuguang Ma, Susan Wong, Jason Halladay, Mary Gates

Drug Metab Dispos· January 2016

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Role of endogenous Schwann cells in tissue repair after spinal cord injury.
Shu-Xin Zhang, Fengfa Huang, Mary Gates, Eric G Holmberg

Neural Regen Res· January 2013

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Somatosensory evoked potentials can be recorded on the midline of the skull with subdermal electrodes in non-sedated rats elicited by magnetic stimulation of the tibial nerve.
Shu-Xin Zhang, Fengfa Huang, Mary Gates, Eric G Holmberg

J Neurosci Methods· July 2012

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Tail nerve electrical stimulation combined with scar ablation and neural transplantation promotes locomotor recovery in rats with chronically contused spinal cord.
Shu-xin Zhang, Fengfa Huang, Mary Gates, Eric G Holmberg

Brain Res· May 2012

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Scar ablation combined with LP/OEC transplantation promotes anatomical recovery and P0-positive myelination in chronically contused spinal cord of rats.
Shu-Xin Zhang, Fengfa Huang, Mary Gates, Eric G Holmberg

Brain Res· July 2011

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Histological repair of damaged spinal cord tissue from chronic contusion injury of rat: a LM observation.
Shu-xin Zhang, Fengfa Huang, Mary Gates, Jason White, Eric G Holmberg

Histol Histopathol· January 2011

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Extensive scarring induced by chronic intrathecal tubing augmented cord tissue damage and worsened functional recovery after rat spinal cord injury.
Shu-xin Zhang, Fengfa Huang, Mary Gates, Jason White, Eric G Holmberg

J Neurosci Methods· August 2010

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Tail nerve electrical stimulation induces body weight-supported stepping in rats with spinal cord injury.
Shu-Xin Zhang, Fengfa Huang, Mary Gates, Jason White, Eric G Holmberg

J Neurosci Methods· March 2010

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Pharmacological characterization of the competitive GLUK5 receptor antagonist decahydroisoquinoline LY466195 in vitro and in vivo.
Brianne Weiss, Andrew Alt, Ann Marie Ogden, Mary Gates, Donna K Dieckman

J Pharmacol Exp Ther· August 2006

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LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease.
Tracey K Murray, Katherine Whalley, Christine S Robinson, Mark A Ward, Caroline A Hicks, Mary Gates

J Pharmacol Exp Ther· August 2003

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Are you too sure of your stand on the right to die?
Mary S Gates, Gloria G Mayer

RN· December 1978

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