Publications by authors named "Massimo Locati"

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Membrane IL-18 identifies a human macrophage subset with distinct proteomic and functional traits.
Chiara Vitale, Andrea Petretto, Katia Cortese, Sonia Carta, Alessandra Dondero, Massimo Locati

Oncoimmunology· December 2025

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Tissue-Specific Immunosuppressive and Proliferating Macrophages Fuel Early Metastatic Progression of Human Colorectal Cancer to the Liver.
Paolo Marzano, Cristiana Soldani, Valentina Cazzetta, Barbara Franceschini, Sara Terzoli, Massimo Locati

Cancer Immunol Res· November 2025

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Anti-inflammatory activity of Pseudomonas aeruginosa DEV phage in cystic fibrosis models.
Marco Cafora, Dorina Dobi, Jonahunnatha Nesson George William, Francesca Forti, Laura Belleri, Massimo Locati

J Cyst Fibros· September 2025

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Synovial MS4A4A correlates with inflammation and counteracts response to corticosteroids in arthritis.
Marie-Astrid Boutet, Irene Mattiola, Rita Silva-Gomes, Alessandra Nerviani, Marina Sironi, Massimo Locati

Proc Natl Acad Sci U S A· September 2025

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Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial.
Gilbert Bensimon, P Nigel Leigh, Timothy Tree, Andrea Malaspina, Christine Am Payan, Massimo Locati

Lancet· May 2025

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Selective expression and significance of ACKR2 in lung aerocytes.
Francesca Albano, Valeria Mollica Poeta, Lucia Zotti, Alessandra Castagna, Arianna Felicetta, Massimo Locati

J Immunother Cancer· January 2025

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AEBS inhibition in macrophages: Augmenting reality for SERMs repurposing against infections.
Chiara Sfogliarini, Lien Hong Tran, Candida Maria Cesta, Marcello Allegretti, Massimo Locati

Biochem Pharmacol· November 2024

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Pharmacometabolomics applied to low-dose interleukin-2 treatment in amyotrophic lateral sclerosis.
Hugo Alarcan, Clément Bruno, Patrick Emond, Cédric Raoul, Patrick Vourc'h, Massimo Locati

Ann N Y Acad Sci· June 2024

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Integrating AI-Powered Digital Pathology and Imaging Mass Cytometry Identifies Key Classifiers of Tumor Cells, Stroma, and Immune Cells in Non-Small Cell Lung Cancer.
Alessandra Rigamonti, Marika Viatore, Rebecca Polidori, Daoud Rahal, Marco Erreni, Massimo Locati

Cancer Res· April 2024

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The immune activity of selective estrogen receptor modulators is gene and macrophage subtype-specific yet converges on Il1b downregulation.
Chiara Sfogliarini, Giovanna Pepe, Candida Maria Cesta, Marcello Allegretti, Massimo Locati

Biomed Pharmacother· September 2023

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Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome.
Rajesh Kumar, Samantha Milanesi, Martyna Szpakowska, Laura Dotta, Dario Di Silvestre, Massimo Locati

JCI Insight· March 2023

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Perioperative corticosteroid treatment impairs tumor-infiltrating dendritic cells in patients with newly diagnosed adult-type diffuse gliomas.
Claudia Carenza, Sara Franzese, Alessandra Castagna, Sara Terzoli, Matteo Simonelli, Massimo Locati

Front Immunol· January 2023

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The impact of tumor associated macrophages on tumor biology under the lens of mathematical modelling: A review.
Pejman Shojaee, Federica Mornata, Andreas Deutsch, Massimo Locati, Haralampos Hatzikirou

Front Immunol· November 2022

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Phosphoproteomic mapping of CCR5 and ACKR2 signaling properties.
Alessandro Vacchini, Elisa Maffioli, Dario Di Silvestre, Cinzia Cancellieri, Samantha Milanesi, Massimo Locati

Front Mol Biosci· November 2022

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Distinct responses of newly identified monocyte subsets to advanced gastrointestinal cancer and COVID-19.
Alessandra Rigamonti, Alessandra Castagna, Marika Viatore, Federico Simone Colombo, Sara Terzoli, Massimo Locati

Front Immunol· October 2022

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Understanding fibrosis pathogenesis via modeling macrophage-fibroblast interplay in immune-metabolic context.
Elisa Setten, Alessandra Castagna, Josué Manik Nava-Sedeño, Jonathan Weber, Roberta Carriero, Massimo Locati

Nat Commun· October 2022

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Differential expression and regulation of MS4A family members in myeloid cells in physiological and pathological conditions.
Rita Silva-Gomes, Sarah N Mapelli, Marie-Astrid Boutet, Irene Mattiola, Marina Sironi, Massimo Locati

J Leukoc Biol· April 2022

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Tamoxifen Twists Again: On and Off-Targets in Macrophages and Infections.
Chiara Sfogliarini, Giovanna Pepe, Arianna Dolce, Sara Della Torre, Maria Candida Cesta, Massimo Locati

Front Pharmacol· March 2022

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ERα-independent NRF2-mediated immunoregulatory activity of tamoxifen.
Giovanna Pepe, Chiara Sfogliarini, Loris Rizzello, Giuseppe Battaglia, Christian Pinna, Massimo Locati

Biomed Pharmacother· December 2021

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Immunotherapeutic early-phase clinical trials and malignant gliomas: A single-center experience and comprehensive immunophenotyping of circulating leukocytes.
Matteo Simonelli, Pasquale Persico, Arianna Capucetti, Claudia Carenza, Sara Franzese, Massimo Locati

Neurooncol Adv· November 2021

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Tumor-Released Products Promote Bone Marrow-Derived Macrophage Survival and Proliferation.
Juliana Maria Motta, Vivian Mary Rumjanek, Alberto Mantovani, Massimo Locati

Biomedicines· October 2021

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The tetraspan MS4A family in homeostasis, immunity, and disease.
Irene Mattiola, Alberto Mantovani, Massimo Locati

Trends Immunol· September 2021

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Amyotrophic lateral sclerosis transcriptomics reveals immunological effects of low-dose interleukin-2.
Ilaria Giovannelli, Nadhim Bayatti, Abigail Brown, Dennis Wang, Marius Mickunas, Massimo Locati

Brain Commun· June 2021

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Endogenous modification of the chemoattractant CXCL5 alters receptor usage and enhances its activity toward neutrophils and monocytes.
Mieke Metzemaekers, Anneleen Mortier, Alessandro Vacchini, Daiane Boff, Karen Yu, Massimo Locati

Sci Signal· March 2021

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Histopathological and Immune Prognostic Factors in Colo-Rectal Liver Metastases.
Alessandra Rigamonti, Friedrich Feuerhake, Matteo Donadon, Massimo Locati, Federica Marchesi

Cancers (Basel)· March 2021

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