Publications by authors named "Mathilde Poussin"

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Mutant KRAS peptide targeted CAR-T cells engineered for cancer therapy.
Alexander Benton, Jiageng Liu, Mathilde A Poussin, Andrea Lang Goldgewicht, Madhara Udawela

Cancer Cell· July 2025

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Editor's Note: In Vivo Persistence, Tumor Localization, and Antitumor Activity of CAR-Engineered T Cells Is Enhanced by Costimulatory Signaling through CD137 (4-1BB).
De-Gang Song, Qunrui Ye, Carmine Carpenito, Mathilde Poussin, Li-Ping Wang

Cancer Res· February 2024

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TCRvβ-CART therapy mediates high-precision targeting of malignant T-cell clones.
Lauren C Shaw, Mathilde Poussin, Alba Rodriguez-Garcia, Joshua Eggold, Nicholas G Minutolo

Blood Adv· May 2023

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Expression of inducible factors reprograms CAR-T cells for enhanced function and safety.
Anže Smole, Alexander Benton, Mathilde A Poussin, Monika A Eiva, Claudia Mezzanotte

Cancer Cell· December 2022

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Dichotomous impact of affinity on the function of T cell engaging bispecific antibodies.
Mathilde Poussin, Arlene Sereno, Xiufeng Wu, Flora Huang, Jason Manro

J Immunother Cancer· July 2021

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Folate Receptor Beta as a Direct and Indirect Target for Antibody-Based Cancer Immunotherapy.
Allison G Roy, J Michael Robinson, Prannda Sharma, Alba Rodriguez-Garcia, Mathilde A Poussin

Int J Mol Sci· May 2021

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CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy.
Alba Rodriguez-Garcia, Rachel C Lynn, Mathilde Poussin, Monika A Eiva, Lauren C Shaw

Nat Commun· February 2021

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Quantitative Control of Gene-Engineered T-Cell Activity through the Covalent Attachment of Targeting Ligands to a Universal Immune Receptor.
Nicholas G Minutolo, Prannda Sharma, Mathilde Poussin, Lauren C Shaw, Daniel P Brown

J Am Chem Soc· April 2020

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CAR T Cells Targeting MISIIR for the Treatment of Ovarian Cancer and Other Gynecologic Malignancies.
Alba Rodriguez-Garcia, Prannda Sharma, Mathilde Poussin, Alina C Boesteanu, Nicholas G Minutolo

Mol Ther· February 2020

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Multiparameter comparative analysis reveals differential impacts of various cytokines on CART cell phenotype and function ex vivo and in vivo.
Xiao-Jun Xu, De-Gang Song, Mathilde Poussin, Qunrui Ye, Prannda Sharma

Oncotarget· December 2016

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Tumor Regression and Delayed Onset Toxicity Following B7-H4 CAR T Cell Therapy.
Jenessa B Smith, Evripidis Lanitis, Denarda Dangaj, Elizabeth Buza, Mathilde Poussin

Mol Ther· November 2016

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Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced by surface antigen expression level.
De-Gang Song, Qunrui Ye, Mathilde Poussin, Jessica A Chacon, Mariangela Figini

J Hematol Oncol· July 2016

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Follicle-Stimulating Hormone Receptor as a Target in the Redirected T-cell Therapy for Cancer.
Katarzyna Urbanska, Caitlin Stashwick, Mathilde Poussin, Daniel J Powell

Cancer Immunol Res· October 2015

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Rigorous optimization and validation of potent RNA CAR T cell therapy for the treatment of common epithelial cancers expressing folate receptor.
Keith Schutsky, D Gang Song, Rachel Lynn, Jenessa B Smith, Mathilde Poussin

Oncotarget· October 2015

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A fully human chimeric antigen receptor with potent activity against cancer cells but reduced risk for off-tumor toxicity.
De-Gang Song, Qunrui Ye, Mathilde Poussin, Lin Liu, Mariangela Figini

Oncotarget· August 2015

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Targeting of folate receptor β on acute myeloid leukemia blasts with chimeric antigen receptor-expressing T cells.
Rachel C Lynn, Mathilde Poussin, Anna Kalota, Yang Feng, Philip S Low

Blood· May 2015

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A human ErbB2-specific T-cell receptor confers potent antitumor effector functions in genetically engineered primary cytotoxic lymphocytes.
Evripidis Lanitis, Jenessa B Smith, Denarda Dangaj, Seleeke Flingai, Mathilde Poussin

Hum Gene Ther· August 2014

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CD137 accurately identifies and enriches for naturally occurring tumor-reactive T cells in tumor.
Qunrui Ye, De-Gang Song, Mathilde Poussin, Tori Yamamoto, Andrew Best

Clin Cancer Res· January 2014

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Chimeric antigen receptor T Cells with dissociated signaling domains exhibit focused antitumor activity with reduced potential for toxicity in vivo.
Evripidis Lanitis, Mathilde Poussin, Alex W Klattenhoff, Degang Song, Raphael Sandaltzopoulos

Cancer Immunol Res· July 2013

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A universal strategy for adoptive immunotherapy of cancer through use of a novel T-cell antigen receptor.
Katarzyna Urbanska, Evripidis Lanitis, Mathilde Poussin, Rachel C Lynn, Brian P Gavin

Cancer Res· April 2012

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Redirected antitumor activity of primary human lymphocytes transduced with a fully human anti-mesothelin chimeric receptor.
Evripidis Lanitis, Mathilde Poussin, Ian S Hagemann, George Coukos, Raphael Sandaltzopoulos

Mol Ther· March 2012

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CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo.
De-Gang Song, Qunrui Ye, Mathilde Poussin, Gretchen M Harms, Mariangela Figini

Blood· January 2012

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In vivo persistence, tumor localization, and antitumor activity of CAR-engineered T cells is enhanced by costimulatory signaling through CD137 (4-1BB).
De-Gang Song, Qunrui Ye, Carmine Carpenito, Mathilde Poussin, Li-Ping Wang

Cancer Res· July 2011

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Evidence for the involvement of ActA in maturation of the Listeria monocytogenes phagosome.
Mathilde A Poussin, Howard Goldfine

Cell Res· January 2010

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The ability of Listeria monocytogenes PI-PLC to facilitate escape from the macrophage phagosome is dependent on host PKCbeta.
Mathilde A Poussin, Michael Leitges, Howard Goldfine

Microb Pathog· January 2009

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