Publications by authors named "Rachel Lynn"

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CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial.
Jay Y Spiegel, Shabnum Patel, Lori Muffly, Nasheed M Hossain, Jean Oak, Rachel Lynn

Nat Med· August 2021

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Dynamic chromatin regulatory landscape of human CAR T cell exhaustion.
David G Gennert, Rachel C Lynn, Jeff M Granja, Evan W Weber, Maxwell R Mumbach

Proc Natl Acad Sci U S A· July 2021

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Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling.
Evan W Weber, Kevin R Parker, Elena Sotillo, Rachel C Lynn, Hima Anbunathan

Science· April 2021

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CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy.
Alba Rodriguez-Garcia, Rachel C Lynn, Mathilde Poussin, Monika A Eiva, Lauren C Shaw

Nat Commun· February 2021

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Strength in Numbers: Identifying Neoantigen Targets for Cancer Immunotherapy.
Rigel J Kishton, Rachel C Lynn, Nicholas P Restifo

Cell· October 2020

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Tuning the Antigen Density Requirement for CAR T-cell Activity.
Robbie G Majzner, Skyler P Rietberg, Elena Sotillo, Rui Dong, Vipul T Vachharajani, Rachel C Lynn

Cancer Discov· May 2020

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c-Jun overexpression in CAR T cells induces exhaustion resistance.
Rachel C Lynn, Evan W Weber, Elena Sotillo, David Gennert, Peng Xu

Nature· December 2019

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Defining 'T cell exhaustion'.
Christian U Blank, W Nicholas Haining, Werner Held, Patrick G Hogan, Axel Kallies, Rachel C Lynn

Nat Rev Immunol· November 2019

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Pharmacologic control of CAR-T cell function using dasatinib.
Evan W Weber, Rachel C Lynn, Elena Sotillo, John Lattin, Peng Xu

Blood Adv· March 2019

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Neurotoxicity Associated with a High-Affinity GD2 CAR-Letter.
Robbie G Majzner, Evan W Weber, Rachel C Lynn, Peng Xu, Crystal L Mackall

Cancer Immunol Res· April 2018

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Intra-tumoral delivery of CXCL11 via a vaccinia virus, but not by modified T cells, enhances the efficacy of adoptive T cell therapy and vaccines.
Edmund K Moon, Liang-Chuan S Wang, Kheng Bekdache, Rachel C Lynn, Albert Lo

Oncoimmunology· January 2018

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Rigorous optimization and validation of potent RNA CAR T cell therapy for the treatment of common epithelial cancers expressing folate receptor.
Keith Schutsky, D Gang Song, Rachel Lynn, Jenessa B Smith, Mathilde Poussin

Oncotarget· October 2015

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Strain-dependent Lethal Toxicity in NKG2D Ligand-targeted CAR T-cell Therapy.
Rachel C Lynn, Daniel J Powell

Mol Ther· October 2015

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Targeting of folate receptor β on acute myeloid leukemia blasts with chimeric antigen receptor-expressing T cells.
Rachel C Lynn, Mathilde Poussin, Anna Kalota, Yang Feng, Philip S Low

Blood· May 2015

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Targeted cancer immunotherapy via combination of designer bispecific antibody and novel gene-engineered T cells.
Katarzyna Urbanska, Rachel C Lynn, Caitlin Stashwick, Archana Thakur, Lawrence G Lum

J Transl Med· December 2014

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Treating tumors with a vaccinia virus expressing IFNβ illustrates the complex relationships between oncolytic ability and immunogenicity.
Liang-Chuan S Wang, Rachel C Lynn, Guanjun Cheng, Edward Alexander, Veena Kapoor

Mol Ther· April 2012

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Tissue exit: a novel control point in the accumulation of antigen-specific CD8 T cells in the influenza a virus-infected lung.
Silke Jennrich, Michael H Lee, Rachel C Lynn, Kristofer Dewberry, Gudrun F Debes

J Virol· April 2012

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A universal strategy for adoptive immunotherapy of cancer through use of a novel T-cell antigen receptor.
Katarzyna Urbanska, Evripidis Lanitis, Mathilde Poussin, Rachel C Lynn, Brian P Gavin

Cancer Res· April 2012

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Regulation of chemotropic guidance of nerve growth cones by microRNA.
Liang Han, Zhexing Wen, Rachel C Lynn, Marie-Laure Baudet, Christine E Holt

Mol Brain· November 2011

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Regulation of acetylcholine receptor clustering by ADF/cofilin-directed vesicular trafficking.
Chi Wai Lee, Jianzhong Han, James R Bamburg, Liang Han, Rachel Lynn

Nat Neurosci· July 2009

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